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ENGASE encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. Additionally we are shipping ENGASE Kits (4) and ENGASE Proteins (3) and many more products for this protein.
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In patients with autosomal dominant polycystic kidney disease, urinary NAGase was correlated with urinary ET-1 (show EDN1 Antibodies) which was inversely associated with eGFR (show EGFR Antibodies) and positively correlated with total kidney volume.
Serological N-acetyl-glucosaminidase (show NAGLU Antibodies), telomere length, and the UCP2 (show UCP2 Antibodies)-886G>A variant are independent risk factors for type 2 diabetes.
As the generation of the bulk of fOS is unaffected by co-down regulation of Ngly1p and Engase1p, alternative quantitatively important mechanisms must underlie the liberation of these fOS from either LLO or glycoproteins during protein N-glycosylation.
O-GlcNAcase (show MGEA5 Antibodies) expression is increased in erythrocytes from both individuals with pre-diabetes and individuals with less well-controlled diabetes.
involved in processing of free oligosaccharides in the cytosol; identification of the gene encoding human cytosolic ENGase
endo-beta-n-acetylglucosaminidase present in the synovial fluid of rheumatoid arthritis patients, may contribute to the depletion of glycosaminoglycans from cartilage allowing the invasion of synovial cells
identification of O-GlcNAcase (show MGEA5 Antibodies) as a caspase-3 (show CASP3 Antibodies) substrate with a novel caspase-3 (show CASP3 Antibodies) cleavage site and provide insight about O-GlcNAcase (show MGEA5 Antibodies) regulation during apoptosis.
ENGase efficiently hydrolyzes phosphorylated oligosaccharides that are larger than Man4GlcNAc2-P, generating GlcNAc-1-P and neutral Gn1 (show GYG1 Antibodies)-type free oligosaccharides.
This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides.
, Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase
, Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
, Cytosolic endo-beta-N-acetylglucosaminidase