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ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009].. Additionally we are shipping ESRP1 Proteins (6) and ESRP1 Kits (3) and many more products for this protein.
Showing 10 out of 46 products:
Human Polyclonal ESRP1 Primary Antibody for IHC (p), WB - ABIN652121
Joo, Correia, Li, Lopez, Baker, Sugrue: Transcriptomic analysis of PNN- and ESRP1-regulated alternative pre-mRNA splicing in human corneal epithelial cells. in Investigative ophthalmology & visual science 2013
Human Polyclonal ESRP1 Primary Antibody for ICC, IF - ABIN4309626
Ishii, Saitoh, Sakamoto, Kondo, Katoh, Tanaka, Motizuki, Masuyama, Miyazawa: Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. in The Journal of biological chemistry 2014
Ptbp1 (show PTBP1 Antibodies) abundance is controlled in Xenopus epidermis via alternate splicing: skipping of exon 11 is the default splicing pattern, but Esrp1 stimulates ptbp1 (show PTBP1 Antibodies) expression by favoring the inclusion of exon 11 up to a level that is limited by Ptbp1 (show PTBP1 Antibodies) itself.
ZEB1 (show ZEB1 Antibodies)-induced epithelial-to-mesenchymal transition and associated molecular changes in ESRP1 and CD44 (show CD44 Antibodies) contribute to early pathogenesis and metastatic potential in established lung cancer
The molecular mechanisms by which ESRP1 and ESPR2 exert positive as well as negative effects on cancer progression have been summarized. (Review)
Recombinant human ESRP1-RRM3 was subjected to biomolecular NMR and its chemical shifts and structural coordinates were determined and deposited in the BioMagResBank and Protein Data Bank respectively. Its interaction with RBPMS2 (show RBPMS2 Antibodies) was mapped.
Altered Expression and Splicing of ESRP1 in Malignant Melanoma Correlates with Epithelial-Mesenchymal Status and Tumor-Associated Immune Cytolytic Activity.
Data show that both rab (show HRB Antibodies) G-Protein RAB25 (show RAB25 Antibodies) and RNA-binding protein (show PTBP1 Antibodies) ESRP1 were suppressed by transcription factor ZEB1 (show ZEB1 Antibodies), which was in turn regulated via epigenetic mechanisms.
MCL1 (show MCL1 Antibodies) with the deletion of 801G and 802A sites could not be correctly spliced by ESRP1 and no significant difference was seen in the expressions of isoform 1 and 3 in mutant MCL1 (show MCL1 Antibodies)
ESRP1 and ESRP2 (show ESRP2 Antibodies) suppress cancer cell motility via different mechanisms.
Results show that ESRP1 regulates the expression pattern of FGFR-2 (show FGFR2 Antibodies) isoforms, attenuates cell growth, migration, invasion and metastasis, and is a favorable prognostic factor in pancreatic ductal adenocarcinoma.
Data suggest that alternative splicing in ESRP1 transcripts in somatotroph adenomas is essential in epithelial-mesenchymal transition progression and in response to somatostatin (show SST Antibodies) analog antineoplastic treatment.
ESRP1 and PNN (show PNN Antibodies) modulate alternative splicing of a specific subset of target genes, but not general splicing events, in HCET cells to maintain or enhance epithelial characteristics.
Loss of both Esrp1 and its paralog Esrp2 (show ESRP2 Antibodies) results in widespread developmental defects with broad implications to human disease.
The expression levels of three splicing factors, ESRP1, PTB (show PTBP1 Antibodies) and SF2/ASF (show SRSF1 Antibodies), are significantly altered during cardiac hypertrophy in mice.
ESRP1 thus acts as a physiological regulator of the finely-tuned balance between self-renewal and commitment to a restricted developmental fate.
Esrp1 could play an important role in the morphological changes underlying embryogenesis of the placenta and embryo.
Alternative splicing of CD44 (show CD44 Antibodies) mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.
Epithelial splicing regulatory proteins 1/2 (ESRP1/2) are epithelial cell-type-specific regulators of FGFR2 (show FGFR2 Antibodies) splicing.
ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009
epithelial splicing regulatory protein 1
, RNA-binding motif protein 35A
, RNA-binding protein 35A
, RNA binding motif protein 35A