anti-Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) Antibodies

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. Additionally we are shipping EIF4A1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF4A1 1973 P60842
EIF4A1 13681 P60843
EIF4A1 287436  
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Top anti-EIF4A1 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-EIF4A1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-EIF4A1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500 <br /> Positive Control:.21_B cell lysate <br /> EIF4A1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-EIF4A1 Pab (ABIN391393) in K562 cell line lysates (35 µg/lane). EIF4A1(arrow) was detected using the purified polyclonal antibody. Western blot analysis of EIF4A1 (arrow) using rabbit polyclonal EIF4A1 Antibody (N-term) (ABIN391393). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the EIF4A1 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$357.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Eif4a1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated IHC (p), WB Western Blot: eIF4A1 Antibody [NBP2-24632] - Analysis of eIF4A1 in K562 cell lysate in the 1) absence and 2) presence of immunizing peptide, and 3) RAW cell lysate in the absence of immunizing peptide using NBP2-24632 at 0.25 ug/ml. Immunohistochemistry-Paraffin: eIF4A1 Antibody [NBP2-24632] - Analysis of eIF4A1 in formalin-fixed, paraffin-embedded human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml. 0.1 mg Log in to see 7 to 9 Days
$317.63
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: eIF4A1 Antibody [NBP2-16302] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:500 dilution. Immunocytochemistry/Immunofluorescence: eIF4A1 Antibody [NBP2-16302] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence (IF) analysis of HeLa with antibody (Left) and DAPI (Right) diluted at 1:100. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: eIF4A1 Antibody [NBP2-16303] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution. Immunohistochemistry-Paraffin: eIF4A1 Antibody [NBP2-16303] - EIF4A1 antibody [N2C2], Internal detects EIF4A1 protein at cytosol on colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma tissue. EIF4A1 antibody [N2C2], Internal dilution: 1:500. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Mouse Rabbit Un-conjugated WB Western Blot: eIF4A1 Antibody [NBP1-98371] - Mouse Pancreas Lysate 1.0ug/ml, Gel Concentration: 12% 100 μL Log in to see 8 to 11 Days
$447.56
Details

EIF4A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-EIF4A1 Antibodies

  1. Dog (Canine) Polyclonal EIF4A1 Primary Antibody for IHC (p), WB - ABIN4307621 : Tamarkin-Ben-Harush, Vasseur, Debart, Ulitsky, Dikstein: Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress. in eLife 2017 (PubMed)

More Antibodies against EIF4A1 Interaction Partners

Human Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) interaction partners

  1. Star-PAP (show TUT1 Antibodies)-specific polyadenylation sites usage regulates the expression of the eukaryotic translation initiation factor (show EIF2A Antibodies) EIF4A1, the tumor suppressor gene PTEN (show PTEN Antibodies) and the long non-coding RNA NEAT1.

  2. our data demonstrate that the common effects of eIF4A1 and eIF4E (show EIF4E Antibodies) on translation are mediated by the coding region and 3'UTR (show UTS2R Antibodies)

  3. our data identify the eIF4F (show EIF4A2 Antibodies) complex as an important upstream regulator of TORC1 (show CRTC1 Antibodies), which acts via TSC2 (show TSC2 Antibodies) to inactivate TORC1 (show CRTC1 Antibodies) upon withdrawal of amino acids

  4. Our results demonstrate that miR (show MLXIP Antibodies)-133a plays a pivotal role in colorectal cancer by inhibiting cell proliferation, invasion, and migration by targeting oncogenic eukaryotic translation initiation factor 4A1, which acts as a tumor suppressor and may provide a new potential therapeutic target in colorectal cancer

  5. miR (show MLXIP Antibodies)-1284 can function as a new regulator to reduce gastric cancer multidrug resistant cells by targeting EIF4A1.

  6. Studies indicate a developing focus on targeting eukaryotic initiation factor 4A (show DDX39 Antibodies) eIF4A1 and eIF4A2 (show EIF4A2 Antibodies) as cancer therapy.

  7. Immunohistochemical analysis was performed on over 3000 breast tumors to investigate the relationship among expression of eIF4A1, the helicase-modulating proteins eIF4B (show EIF4B Antibodies), eIF4E (show EIF4E Antibodies) and PDCD4 (show PDCD4 Antibodies), and clinical outcome.

  8. Collectively, these data suggested that a potential role of NS4A in antagonizing host antiviral defense is by recruiting eIF4AI and escaping the translation inhibition mediated by PKR (show PKLR Antibodies).

  9. eIF4A functions as an adenosine triphosphate-dependent processive helicase when complexed with two accessory proteins, eIF4G (show EIF4G1 Antibodies) and eIF4B (show EIF4B Antibodies).

  10. demonstrate that DAP5 associates with eIF2beta and eIF4AI to stimulate IRES-dependent translation of cellular mRNAs

Mouse (Murine) Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) interaction partners

  1. the central A-rich domains of BC RNAs target eIF4A, specifically inhibiting its RNA helicase activity

  2. analysis of the tandem MA-3 (show PDCD6 Antibodies) region of Pdcd4 (show PDCD4 Antibodies) protein and characterization of its interactions with eIF4A and eIF4G (show EIF4G1 Antibodies)

  3. Pdcd4 (show PDCD4 Antibodies) binding to eIF4A is linked to its transformation-suppressing activity, as Pdcd4 (show PDCD4 Antibodies)-eIF4A binding and consequent inhibition of translation are required for Pdcd4 (show PDCD4 Antibodies) transrepression of AP-1 (show JUN Antibodies).

  4. The binding of pateamine to eIF4A presets the protein in the high-affinity RNA-binding state, which stimulates ATP binding, hydrolysis, and RNA unwinding.

  5. interactions between Pdcd4 (show PDCD4 Antibodies) and components of the translation initiation complex, namely, the RNA helicase eIF4A and the scaffolding protein eIF4G (show EIF4G1 Antibodies)

  6. analysis of cells of eIF4GIf molecules lacking either the PABP (show EBP Antibodies)-binding site, the eIF3 (show EIF3A Antibodies)-binding site, the middle domain eIF4A-binding site, or the C-terminal segment that includes the second eIF4A-binding site

EIF4A1 Antigen Profile

Protein Summary

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).

Gene names and symbols associated with EIF4A1

  • eukaryotic translation initiation factor 4A1 (eif4a1) antibody
  • eukaryotic translation initiation factor 4A1 (EIF4A1) antibody
  • eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1) antibody
  • eukaryotic translation initiation factor 4A1 (Eif4a1) antibody
  • BM-010 antibody
  • Ddx2a antibody
  • EIF-4A antibody
  • eIF-4A-I antibody
  • Eif4 antibody
  • EIF4A antibody
  • eIF4A-I antibody

Protein level used designations for EIF4A1

translation initiation factor eIF4A I , eukaryotic translation initiation factor 4A1 , eukaryotic translation initiation factor 4A, isoform 1 , eukaryotic translation initiation factor 4A , eukaryotic initiation factor 4A-I , eukaryotic translation initiation factor 4A-like , eukaryotic initiation factor 4A-I-like , ATP-dependent RNA helicase eIF4A-1 , eIF-4A-I , eIF4A-I , eukaryotic initiation factor 4AI , initiation factor eIF-4A long form

GENE ID SPECIES
443739 Xenopus laevis
479485 Canis lupus familiaris
496556 Xenopus (Silurana) tropicalis
100061902 Equus caballus
100101929 Sus scrofa
100355889 Oryctolagus cuniculus
100388544 Callithrix jacchus
100582095 Nomascus leucogenys
748995 Pan troglodytes
1973 Homo sapiens
13681 Mus musculus
287436 Rattus norvegicus
695050 Macaca mulatta
100173783 Pongo abelii
100688577 Canis lupus familiaris
504958 Bos taurus
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