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anti-Exocyst Complex Component 2 (EXOC2) Antibodies

The protein encoded by EXOC2 is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EXOC2 55770 Q96KP1
EXOC2 66482 Q9D4H1
EXOC2 171455 O54921
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Top anti-Exocyst Complex Component 2 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Prostate (formalin-fixed, paraffin-embedded) stained with EXOC2 antibody ABIN213650 at 20-40 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-EXOC2/SEC5 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC (p), ELISA 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

EXOC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Exocyst Complex Component 2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Exocyst Complex Component 2 (EXOC2) interaction partners

  1. Sec5 concentrates at the sub-apical complex, indicating a role for Sec5 in the polarized epithelium.

  2. Germline clones of sec5 possess defects in membrane addition and the posterior positioning of the oocyte.

  3. Sec5, Sec6 (show EXOC3 Antibodies) and Sec8 (show EXOC4 Antibodies) act as a complex, each member dependent on the others for proper localization and function

  4. Rab11 forms a complex with Sec5. Sec5 interacts with Sec6 suggesting the exocyst is a Rab11 effector that facilitates protein transport to the apical rhabdomere in Drosophila photoreceptors

  5. The Drosophila exocyst component sec5 in epithelial cells results in DE-Cad (show CAD Antibodies) accumulation in an enlarged Rab11 (show RAB11A Antibodies) recycling endosomal compartment and inhibits DE-Cad (show CAD Antibodies) delivery to the membrane.

Human Exocyst Complex Component 2 (EXOC2) interaction partners

  1. data suggest that the induction of SGK1 (show SGK1 Antibodies) through treatment with dexamethasone alters MT dynamics to increase Sec5-GEF-H1 (show ARHGEF2 Antibodies) interactions, which promote GEF-H1 (show ARHGEF2 Antibodies) targeting to adhesion sites.

  2. Exocyst sec5 regulates exocytosis of newcomer insulin (show INS Antibodies) granules underlying biphasic insulin (show INS Antibodies) secretion.

  3. We identified interactions between RalA (show rala Antibodies) and its effectors sec5 and exo84 (show EXO84 Antibodies) in the Exocyst complex as directly necessary for migration and invasion of prostate cancer tumor cells.

  4. Data show that Mc1R (show MSHR Antibodies), HERC2 (show HERC2 Antibodies), IRF4 (show IRF4 Antibodies), TYR (show TYR Antibodies) and EXOC2 are ranked highest in hair color prediction analysis.

  5. shRNA-mediated knockdown of the Ral effector proteins Sec5 and Exo84, but less so in the case of RalBP1, reduced oncogenic RalGEF-mediated transformation and oncogenic Ras-driven tumorigenic growth of human cells.

  6. SEC5 has been identified as a binding partner of deafness locus putative guanine nucleotide exchange factor (show RASGRF1 Antibodies).

  7. evidence that mammalian exocyst components are present as distinct subcomplexes on vesicles and the plasma membrane and that Ral (show rala Antibodies) GTPases regulate the assembly interface of a full octameric exocyst complex through interaction with Sec5 and Exo84 (show EXO84 Antibodies)

  8. These observations define the mechanistic contribution of RalGTPases to cancer cell survival and reveal the RalB (show Ralb Antibodies)/Sec5 effector complex as a component of TBK1 (show TBK1 Antibodies)-dependent innate immune signaling.

  9. Localization of Exocyst and, by extension, targeting of Exocyst-dependent cargo, is dependent on Ral (show rala Antibodies) GTPases, which control association between Sec5 and paxillin (show PXN Antibodies).

Mouse (Murine) Exocyst Complex Component 2 (EXOC2) interaction partners

  1. Exocyst sec5 regulates exocytosis of newcomer insulin (show INS Antibodies) granules underlying biphasic insulin (show INS Antibodies) secretion.

  2. the structure of the Ral (show rala Antibodies)-binding domain of Sec5

Arabidopsis thaliana Exocyst Complex Component 2 (EXOC2) interaction partners

  1. SEC5a copurifies in a high molecular mass fraction of 900 kD, and functions as a subunit in a exocyst complex that plays important roles in morphogenesis.

Exocyst Complex Component 2 (EXOC2) Antigen Profile

Protein Summary

The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with EXOC2

  • CG8843 gene product from transcript CG8843-RA (sec5) antibody
  • exocyst complex component 2 (EXOC2) antibody
  • exocyst complex component 2 (LOC100226726) antibody
  • exocyst complex component 2 (Exoc2) antibody
  • exocyst complex component sec5 (SEC5A) antibody
  • Protein SEC-5 (sec-5) antibody
  • 2410030I24Rik antibody
  • AI648199 antibody
  • CG8843 antibody
  • Dmel\\CG8843 antibody
  • dsec5 antibody
  • exocyst complex component sec5 antibody
  • F7O12.2 antibody
  • F7O12_2 antibody
  • Rsec5 antibody
  • Sec-5 antibody
  • SEC5 antibody
  • Sec5l1 antibody
  • Sec5p antibody

Protein level used designations for EXOC2

CG8843-PA , sec5-PA , exocyst complex component 2 , SEC5-like 1 , exocyst complex component Sec5 , SEC5 homolog

GENE ID SPECIES
33563 Drosophila melanogaster
420889 Gallus gallus
100226726 Taeniopygia guttata
55770 Homo sapiens
66482 Mus musculus
171455 Rattus norvegicus
844020 Arabidopsis thaliana
174459 Caenorhabditis elegans
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