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Fructose-1,6-Bisphosphatase 1 Proteins (FBP1)

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Additionally we are shipping FBP1 Antibodies (70) and FBP1 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBP1 14275  
FBP1 2203 P09467
FBP1 24362 P19112
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Top FBP1 Proteins at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$315.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Human Cells Human His tag   50 μg Log in to see 5 Days
$280.50
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$280.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,907.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,911.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,911.33
Details

FBP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
,
Rat (Rattus)

Top referenced FBP1 Proteins

  1. Human FBP1 Protein expressed in Escherichia coli (E. coli) - ABIN666902 : Hirota, Miyoshi, Kugou, Hoffman, Shibata, Ohta: Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs. in Nature 2008 (PubMed)
    Show all 2 references for ABIN666902

More Proteins for Fructose-1,6-Bisphosphatase 1 (FBP1) Interaction Partners

Arabidopsis thaliana Fructose-1,6-Bisphosphatase 1 (FBP1) interaction partners

  1. Results indicate that NDH is specifically upregulated in hcef1, allowing for increased CEF1 (show CDC5L Proteins) and the hcef1 mutation imposes an elevated ATP demand that may trigger CEF1 (show CDC5L Proteins). [CEF1 (show CDC5L Proteins)]

Mouse (Murine) Fructose-1,6-Bisphosphatase 1 (FBP1) interaction partners

  1. Folate receptor (show FOLR3 Proteins) expression on murine and human adipose tissue macrophages

  2. Quantitative RT-PCR showed that Slc19a1 (show SLC19A1 Proteins) mRNA was expressed in mouse cumulus-oocyte complexes (COCs) and oocytes, whereas Folr1 (show FOLR1 Proteins) showed expression only in preimplantation embryos, increasing from the 2-cell stage onward.

  3. The Identification of FBPase interacting partners with mass spectrometry reveals a set of nuclear proteins involved in cell cycle regulation, mRNA processing and in stabilization of genomic DNA structure.

  4. under conditions of reduced folate (Folr (show FOLR1 Proteins)-/-) signalling, pathways crucial for proper development of the neural tube are significantly altered.

  5. Nesting of T helper cell epitopes results in recruitment of latent pools of naive high-affinity/avidity folate receptor (show FOLR3 Proteins) (FR)alpha (show FOLR1 Proteins)-specific T cells, which have the ability to home to tumors expressing FRalpha and to reduce tumor burden.

  6. FBPase plays an important role in regulating glucose sensing and insulin (show INS Proteins) secretion of beta-cells and serves a promising target for diabetes treatment.

  7. Data show that NF-kappaB (show NFKB1 Proteins) functions downstream of Ras to promote epigenetic downregulation of FBP1 (show FBP2 Proteins).

  8. Fbp1 (show FBP2 Proteins) has a role in anterior neural tube closure

  9. Abnormal heart looping was observed during early development of Folr1 (show FOLR1 Proteins)(-/-) embryos partially rescued by maternal folinic acid supplementation.

  10. folate receptor (show FOLR3 Proteins) type beta is induced in a bone marrow engraftment model of acute myelogenous leukemia

Human Fructose-1,6-Bisphosphatase 1 (FBP1) interaction partners

  1. identified Zinc finger E-box-binding homeobox 1 (ZEB1) bond to FBP1 promoter to enhance DNA methylation in lung cancer cells. Our findings indicate that the down-regulation of FBP1 is a critical oncogenic event in lung cancer progression

  2. FBP1 expression, which is closely correlated with c-Myc (show MYC Proteins) expression, is an independent prognostic factor and promotes nasopharyngeal carcinoma progression.

  3. NPM1 (show NPM1 Proteins) promotes aerobic glycolysis and tumor progression in patients with pancreatic cancer by inhibiting FBP1

  4. There was a negative correlation with the level of FBP1 and recurrence of the lung cancer

  5. the gluconeogenic enzyme fructose-1,6-bisphosphatase 1 (FBP1) is uniformly depleted in over six hundred clear cell renal cell carcinoma (show MOK Proteins) tumours examined.

  6. Ca(2 (show CA2 Proteins)+) affects conformation of the catalytic loop 52-72 of muscle FBPase and inhibits its activity by competing with activatory divalent cations, e.g. Mg(2 (show MUC7 Proteins)+) and Zn(2+).

  7. Case Reports: present reliable diagnostic system to verify an FBPase deficiency and find the genetic aberration.

  8. A novel missense mutation (c.841G>A) in the FBP1 gene seems to be prevalent in Pakistani-Indian patients with fructose-1,6-bisphosphatase deficiency.

  9. A homozygous c.658delT mutation was detected at exon 5 of the FBP1 gene in the two siblings with FBPase deficiency.

  10. LSD1 (show KDM1A Proteins) regulates transcription activation of two gluconeogenic genes, FBP1 and G6Pase (show G6PC Proteins).

Pig (Porcine) Fructose-1,6-Bisphosphatase 1 (FBP1) interaction partners

  1. Directed mutations, kinetics, and structure determinations link the central cavity of FBP to AMP (show TMPRSS5 Proteins)/fructose 2,6-bisphosphate synergism.

  2. The AMP (show TMPRSS5 Proteins)/Mg(2 (show MCOLN1 Proteins)+) and AMP (show TMPRSS5 Proteins)/Zn(2+) complexes of Asp (show ASIP Proteins)(10) FBPase are in intermediate quaternary conformations.

  3. each subunit in the wild-type tetramer can independently achieve maximum velocity when activated by Mg(2 (show MCOLN1 Proteins)+); findings are fully consistent with a mechanism of cooperativity that arises from within a single subunit of fructose-1,6-bisphosphatase.

  4. Ca2 (show CA2 Proteins)+ appears to be a strong inhibitor of muscle FBPase (fructose 1,6-diphosphatase).

FBP1 Protein Profile

Protein Summary

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.

Gene names and symbols associated with FBP1

  • fructose-1,6-bisphosphatase (fbp)
  • fructose-1,6-bisphosphatase 1b (fbp1b)
  • fructose-1,6-bisphosphatase (fbp2)
  • fructose-1,6-bisphosphatase 1 (FBP1)
  • fructose-1,6-bisphosphatase (HCEF1)
  • Fructose-1,6-bisphosphatase (FBP1)
  • fructose-1,6-bisphosphatase (FBP1)
  • fbp (fbp)
  • fructose-1,6-bisphosphatase (fbp1)
  • folate receptor 1 (adult) (Folr1)
  • fructose bisphosphatase 1 (Fbp1)
  • fructose-1,6-bisphosphatase 1 (Fbp1)
  • fructose-1,6-bisphosphatase 1a (fbp1a)
  • cb598 protein
  • CG10611 protein
  • CG31692 protein
  • Dmel\\CG31692 protein
  • fb57b01 protein
  • FBP protein
  • Fbp-2 protein
  • FBP1 protein
  • fbp1l protein
  • Fbp2 protein
  • Fbp3 protein
  • FbPase protein
  • Fdp protein
  • fk92h02 protein
  • Folbp-1 protein
  • Folbp1 protein
  • high cyclic electron flow 1 protein
  • id:ibd1091 protein
  • wu:fb17g10 protein
  • wu:fb57b01 protein
  • wu:fk92h02 protein
  • xcc-b100_0105 protein
  • zgc:64096 protein
  • zgc:64127 protein

Protein level used designations for FBP1

CG31692-PA , CG31692-PB , fbp-PA , fbp-PB , fb17g10 , fructose-1,6-bisphosphatase 1 , fructose-1,6-bisphosphatase , Fructose-1,6-bisphosphatase , FR-alpha , folate binding protein 1 , folate receptor alpha , folate-binding protein 1 , D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 , D-fructose-1,6-bisphosphate 1-phosphohydrolase 3 , FBPase brain isoform , FBPase liver , fructose-1,6-bisphosphatase isozyme 3 , FBPase 1 , fructose-bisphosphatase 1 , growth-inhibiting protein 17 , fructose 1,6-bisphosphatase , Fructose-16- biphosphatase , fructose-1,6- biphosphatase 1 , fructose-1,6-bisphosphatase 1, like

GENE ID SPECIES
35265 Drosophila melanogaster
282672 Danio rerio
398365 Xenopus laevis
465260 Pan troglodytes
709022 Macaca mulatta
824572 Arabidopsis thaliana
1113867 Lactococcus lactis subsp. lactis Il1403
2660720 Bordetella bronchiseptica RB50
3091029 Burkholderia mallei ATCC 23344
3128891 Haloarcula marismortui ATCC 43049
3179489 Aromatoleum aromaticum EbN1
3480984 Pseudomonas protegens Pf-5
4850792 Scheffersomyces stipitis CBS 6054
5716571 Chlamydomonas reinhardtii
6267501 Bordetella avium 197N
6320941 Xanthomonas campestris pv. campestris str. B100
6357652 Burkholderia multivorans ATCC 17616
100136618 Oncorhynchus mykiss
100194619 Salmo salar
14275 Mus musculus
14121 Mus musculus
2203 Homo sapiens
476299 Canis lupus familiaris
397038 Sus scrofa
513483 Bos taurus
100008863 Oryctolagus cuniculus
24362 Rattus norvegicus
395218 Gallus gallus
101113198 Ovis aries
335231 Danio rerio
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