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FUCA2 encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. Additionally we are shipping FUCA2 Proteins (8) and FUCA2 Kits (7) and many more products for this protein.
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Human Polyclonal FUCA2 Primary Antibody for IHC (p), WB - ABIN391985
Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003
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Genetic polymorphisms within the FUCA2 and IL18 (show IL18 Antibodies) gene regions are also associated with diastolic function in SCD (show SCD Antibodies), likely by affecting expression levels of the genes
IL-13 (show IL13 Antibodies), IL-4 (show IL4 Antibodies) and IL-5 (show IL5 Antibodies) have no effect on the expression of FUCA1 (show FUCA1 Antibodies) and FUCA2, but its expression is upregulated by IFN-gamma (show IFNG Antibodies), a Th1 (show TH1L Antibodies) cytokine.
serum alpha-L-fucosidase (show Fuca Antibodies) was identified as a useful marker for close monitoring of patients during post-treatment follow-up
Findings not only demonstrate an important connection between FUCA2 and the adhesion, growth, and pathogenicity of H. pylori, but also support the idea that FUCA2 is a potential target for diagnosis and therapy of H. pylori-related diseases.
This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells.
fucosidase, alpha-L- 2, plasma
, plasma alpha-L-fucosidase
, alpha-L-fucosidase 2
, alpha-L-fucoside fucohydrolase 2
, plasma alpha-L-fucosidase-like
, methylthioribulose-1-phosphate dehydratase
, fuculose-1-phosphate aldolase