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FUS Proteins

(Fused in Sarcoma (FUS))
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].

10 results

custom-made FUS Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7556499
 
custom-made FUS Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7547755
 
FUS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Catalog No. ABIN7123020
 
FUS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 5 references
Catalog No. ABIN2721461
 
FUS Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, ELISA, WB
Catalog No. ABIN7577091
 
FUS Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, ELISA, WB
Catalog No. ABIN7577090
 
FUS Origin: Human respiratory syncytial virus A Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5714158
 
FUS Origin: Human respiratory syncytial virus B Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5714278
 
FUS Origin: Canine Distemper Virus (CDV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710740
 
FUS Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA
Catalog No. ABIN1608021
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reactivity
    • Human
    • Canine Distemper Virus (CDV)
    • Human respiratory syncytial virus A
    • Human respiratory syncytial virus B
    • Mouse
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
  • Binding Specificity
    • AA 1-198
    • AA 1-518
    • AA 1-526
    • AA 136-608
    • AA 137-574
    • AA 27-529
    • AA 287-376
    • partial
  • Conjugate
    • His tag
    • His-SUMO Tag
    • GST tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • Signalway
    • CUSABIO
    • OriGene

Latest Publications for our FUS Proteins

Bogaert, Boeynaems, Kato, Guo, Caulfield, Steyaert, Scheveneels, Wilmans, Haeck, Hersmus, Schymkowitz, Rousseau, Shorter, Callaerts, Robberecht, Van Damme, Van Den Bosch: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).

Gorthi, Romero, Loranc, Cao, Lawrence, Goodale, Iniguez, Bernard, Masamsetti, Roston, Lawlor, Toretsky, Stegmaier, Lessnick, Chen, Bishop: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).

Blokhuis, Koppers, Groen, van den Heuvel, Dini Modigliani, Anink, Fumoto, van Diggelen, Snelting, Sodaar, Verheijen, Demmers, Veldink, Aronica, Bozzoni, den Hertog, van den Berg, Pasterkamp: "Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 175-96, (2016) (PubMed).

Altmeyer, Neelsen, Teloni, Pozdnyakova, Pellegrino, Grøfte, Rask, Streicher, Jungmichel, Nielsen, Lukas: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).

Groen, Fumoto, Blokhuis, Engelen-Lee, Zhou, van den Heuvel, Koppers, van Diggelen, van Heest, Demmers, Kirby, Shaw, Aronica, Spliet, Veldink, van den Berg, Pasterkamp: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).

Aliases for FUS Proteins

FUS RNA binding protein (FUS) Proteins
fused in sarcoma (Fus) Proteins
FUS RNA binding protein (Fus) Proteins
fused in sarcoma (FUS) Proteins
ALS6 Proteins
D430004D17Rik Proteins
D930039C12Rik Proteins
ETM4 Proteins
FUS/TLS Proteins
FUS1 Proteins
Fus1 Proteins
HNRNPP2 Proteins
POMP75 Proteins
TLS Proteins
Tls Proteins
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