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anti-Fyn-Related Kinase (FRK) Antibodies

The protein encoded by FRK belongs to the TYR family of protein kinases. Additionally we are shipping FRK Proteins (7) and FRK Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FRK 25468 P63142
FRK 2444 P42685
FRK 14302 Q922K9
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Top anti-FRK Antibodies at antibodies-online.com

Showing 10 out of 139 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FRK Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-FRK  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate  FRK is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FRK Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using FRK Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FRK Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded human Breast tissues using FRK mouse mAb. Figure 2: Western blot analysis using FRK mouse mAb against truncated FRK-His recombinant protein (1) . 100 μL Log in to see 3 to 4 Days
$345.40
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using FRK mouse mAb against K562 cell lysate (1) . 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, IF, WB Anti-FRK mouse monoclonal antibody (ABIN2453819) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FRK (RC204460). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FRK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-FRK. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 10 to 11 Days
$428.57
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of FRK (arrow) using rabbit polyclonal FRK Antibody (V28) (ABIN392097). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FRK gene. FRK Antibody (N-term) (ABIN392097)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 μg of whole cell lysate) A:MOLT4, 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details

FRK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FRK Antibodies

  1. Human Monoclonal FRK Primary Antibody for WB - ABIN2869328 : Cance, Craven, Weiner, Liu: Novel protein kinases expressed in human breast cancer. in International journal of cancer. Journal international du cancer 1993 (PubMed)
    Show all 3 references for ABIN2869328

  2. Human Monoclonal FRK Primary Antibody for IHC, ELISA - ABIN969157 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 references for ABIN969157

  3. Cow (Bovine) Polyclonal FRK Primary Antibody for WB - ABIN2785801 : Zhang, Gong, Wang, Wang, Ran: [Deoxycholate induces apoptosis in cultured normal human esophageal mucosal epithelial cells]. in Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 2005 (PubMed)
    Show all 2 references for ABIN2785801

  4. Chicken Polyclonal FRK Primary Antibody for WB - ABIN2774079 : Zhang, Wolf-Yadlin, Ross, Pappin, Rush, Lauffenburger, White: Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. in Molecular & cellular proteomics : MCP 2005 (PubMed)
    Show all 2 references for ABIN2774079

  5. Human Monoclonal FRK Primary Antibody for ELISA, WB - ABIN969494 : Cance, Craven, Bergman, Xu, Alitalo, Liu: Rak, a novel nuclear tyrosine kinase expressed in epithelial cells. in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995 (PubMed)

  6. Human Polyclonal FRK Primary Antibody for IF, IHC - ABIN1533731 : Lee, Wang, Luoh, Wood, Scadden: Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene. in Gene 1994 (PubMed)

More Antibodies against FRK Interaction Partners

Human Fyn-Related Kinase (FRK) interaction partners

  1. antagomir-1290 significantly inhibited the proliferation, clonogenicity, invasion, and migration of CD133(+) cells by targeting fyn (show FYN Antibodies)-related Src (show SRC Antibodies) family tyrosine kinase (show TXK Antibodies).

  2. our results demonstrate a combined mechanism for the anti-proliferative effects of FRK by inhibiting cyclin D1 (show CCND1 Antibodies) nucleus accumulation and pRb (show RB1 Antibodies) phosphorylation in glioma cells.

  3. FRK over-expression promoted beta-catenin (show CTNNB1 Antibodies) translocation to the plasma membrane, where it formed complex with N-cadherin (show CDH2 Antibodies).

  4. exome sequencing identified recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 (show STAT3 Antibodies) activation, and cell proliferation sensitive to Src (show SRC Antibodies) inhibitors

  5. Data indicaate that the Rak/Frk SH2 and SH3 domains collaborate to increase the Rak-EGFR (show EGFR Antibodies) interaction.

  6. The expression levels of FRK were significantly correlated with invasiveness in both Hep3B and HepG2 tumor cell lines.

  7. these results clearly indicate that FRK may play a protective role against the progression of glioma by suppressing cell migration and invasion

  8. Genetic variation near FRK/COL10A1 (show COL10A1 Antibodies) and VEGFA (show VEGFA Antibodies) are associated with advanced age-related macular degeneration.

  9. Study searched for mutations in the FRK gene, a recently identified tumor suppressor gene, for the first time in NSCLC. Somatic FRK mutations were found at a very low frequency in NSCLCs.

  10. Breast cancer cell line proliferation blocked by the Src (show SRC Antibodies)-related Rak tyrosine kinase (show TXK Antibodies)

Mouse (Murine) Fyn-Related Kinase (FRK) interaction partners

  1. Characterization of mice deficient in the Src (show SRC Antibodies) family nonreceptor tyrosine kinase (show TYRO3 Antibodies) Frk/rak. Decreases in the circulating levels of T3 but not T4 are reminiscent of euthyroid sick syndrome, a stress-associated clinical condition

  2. The tyrosine kinases Brk/PTK6/Sik (show PTK6 Antibodies), Srm (show SRM Antibodies), Frk/Rak/Gtk/Iyk/Bsk (show EPHA5 Antibodies), and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases. The exon structure of these kinases, called the Brk (show PTK6 Antibodies) family, is highly conserved and distinct.

  3. Experiments with Fyn (show FYN Antibodies)-deficient mice indicate that Fyn (show FYN Antibodies) genotype does not influence ethanol consumption, neither under basal conditions nor following a deprivation period or stress.

  4. These results show that FRK affects beta cell number during embryogenesis and early in life, but is probably redundant for beta cell number and function in adult animals under normal conditions.

FRK Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.

Gene names and symbols associated with FRK

  • potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2) antibody
  • Fyn-related kinase (FRK) antibody
  • fyn-related kinase (FRK) antibody
  • fyn-related kinase (frk) antibody
  • fyn-related kinase (Frk) antibody
  • BK2 antibody
  • BSK antibody
  • BSK/IYK antibody
  • C85044 antibody
  • FRK antibody
  • GTK antibody
  • NGK1 antibody
  • PTK5 antibody
  • RAK antibody

Protein level used designations for FRK

Potassium (K+) channel protein alpha 2, voltage dependent , RAK , RBK2 , RCK5 , potassium voltage gated channel shaker related subfamily member 2 , potassium voltage-gated channel subfamily A member 2 , voltage-gated potassium channel subunit Kv1.2 , hypothetical protein LOC583550 , fyn-related kinase , tyrosine-protein kinase FRK-like , PTK5 protein tyrosine kinase 5 , nuclear tyrosine protein kinase RAK , protein-tyrosine kinase 5 , tyrosine-protein kinase FRK , B-cell src-homology tyrosine kinase , beta-cell Src-homology tyrosine kinase , intestine tyrosine kinase , GASK , GTK , gastrointestinal-associated kinase , gastrointestinal-associated tyrosine kinase , src related tyrosine kinase

GENE ID SPECIES
25468 Rattus norvegicus
583550 Strongylocentrotus purpuratus
481970 Canis lupus familiaris
462953 Pan troglodytes
716267 Macaca mulatta
100403046 Callithrix jacchus
100448548 Pongo abelii
100488362 Xenopus (Silurana) tropicalis
100540680 Meleagris gallopavo
100593495 Nomascus leucogenys
2444 Homo sapiens
421747 Gallus gallus
509227 Bos taurus
14302 Mus musculus
79209 Rattus norvegicus
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