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anti-GIPC PDZ Domain Containing Family, Member 1 (GIPC1) Antibodies

GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009].. Additionally we are shipping GIPC1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GIPC1 10755 O14908
GIPC1 67903 Q9Z0G0
GIPC1 83823 Q9Z254
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Top anti-GIPC1 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GIPC1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate WB Suggested Anti-GIPC1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GIPC1 Antibody (N-term) in mouse bladder tissue lysates (35ug/lane). This demonstrates the GIPC1 antibody detected the GIPC1 protein (arrow). Western blot analysis of GIPC1 Antibody (N-term) in U251 cell line lysates (35ug/lane). This demonstrates the GIPC1 antibody detected the GIPC1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185138 staining (0.03µg/ml) of human HeLa cell lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF, IP, WB   50 μg Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated WB GIPC1 Antibody (N-term)  western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the GIPC1 antibody detected the GIPC1 protein (arrow). GIPC1 Antibody (N-term)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the GIPC1 antibody detected the GIPC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using GIPC1, antibody at 1:100 dilution. WB Image Sample (30 ug of whole cell lysate) A: A431 , B: Hela 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with GIPC1 antibody ABIN214108 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details

GIPC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GIPC1 Antibodies

  1. Human Polyclonal GIPC1 Primary Antibody for EIA, WB - ABIN952519 : Wu, Haruta, Wei: GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN952519

  2. Human Polyclonal GIPC1 Primary Antibody for IF, IP - ABIN488012 : Hasson, Mooseker: Porcine myosin-VI: characterization of a new mammalian unconventional myosin. in The Journal of cell biology 1994 (PubMed)
    Show all 2 references for ABIN488012

  3. Cow (Bovine) Polyclonal GIPC1 Primary Antibody for WB - ABIN374381 : Khetani, Riordon, Tiwari, Momenpour, Godin, Anis: Hollow core photonic crystal fiber as a reusable Raman biosensor. in Optics express 2013 (PubMed)

  4. Cow (Bovine) Polyclonal GIPC1 Primary Antibody for WB - ABIN2778948 : Repetto, Salani, Maggi, Cordera: Insulin and IGF-I phosphorylate eNOS in HUVECs by a caveolin-1 dependent mechanism. in Biochemical and biophysical research communications 2005 (PubMed)

  5. Human Polyclonal GIPC1 Primary Antibody for ELISA, WB - ABIN185138 : De Vries, Lou, Zhao, Zheng, Farquhar: GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)

More Antibodies against GIPC1 Interaction Partners

Arabidopsis thaliana GIPC PDZ Domain Containing Family, Member 1 (GIPC1) interaction partners

  1. TIP1;1 and TIP1;2 single or double mutants did not show significant changes in water content or water retention, and showed no sign of early senescence or growth retardation. [TIP1;2]

Zebrafish GIPC PDZ Domain Containing Family, Member 1 (GIPC1) interaction partners

  1. Morpholino knockdown of synectin in zebrafish impaired formation of the thoracic duct, due to selective defects in (show PROX1 Antibodies)lymphangiogenic but not angiogenic sprouting.

Xenopus laevis GIPC PDZ Domain Containing Family, Member 1 (GIPC1) interaction partners

  1. Silencing of gipc1 in tadpoles caused lymphatic defects due to an underdevelopment and impaired migration of Prox-1 (show PROX1 Antibodies)(+) lymphatic endothelial cells.

  2. Results indicate that kermit 2/XGIPC is a novel component of the IGF pathway, potentially functioning through modulation of the IGF1 (show IGF1 Antibodies) receptor.

Human GIPC PDZ Domain Containing Family, Member 1 (GIPC1) interaction partners

  1. Drd3 (show DRD3 Antibodies) palmitoylation acts as a molecular switch for Drd3 (show DRD3 Antibodies)-biased signaling via a GIPC1-dependent route, which is likely to affect the mode of action of antipsychotic drugs.

  2. The composite biomarker, CAPG (show NCAPG Antibodies) and GIPC1 in primary breast tumors, predicted disease outcomes and benefit from zoledronate and may facilitate patient selection for adjuvant bisphosphonate treatment.

  3. GIPC status determines the loading of cellular cargo in the exosome in pancreatic cancer cells.

  4. GIPC binds LPA(1 (show LPAR1 Antibodies)) and promotes its trafficking from APPL (show APPL1 Antibodies)-containing signaling endosomes to EEA1 (show EEA1 Antibodies) early endosomes and thus attenuates LPA (show APOA Antibodies)-mediated Akt (show AKT1 Antibodies) signaling from APPL (show APPL1 Antibodies) endosomes.

  5. Our results do not show a predictive or prognostic function of GIPC1/Synectin expression for the outcome of radiotherapy in prostate cancer.

  6. a novel non-Smad (show SMAD1 Antibodies) function for endoglin (show ENG Antibodies) and GIPC in regulating endothelial cell function during angiogenesis

  7. The placental lectins reduced the binding of IGF-I (show IGF1 Antibodies) to IGF-1 (show IGF1 Antibodies) receptor in a dose-dependent manner.

  8. Knockdown of ADRM1 (show Adrm1 Antibodies) in amplified ovarian cell-line OAW42 results in downregulation of growth factor GIPC1 and upregulation of tumor-suppressor RECK (show RECK Antibodies) RNA and protein

  9. GIPC1 plays an essential role in oncogenic transformation, and its expression is necessary for the survival of human breast and colorectal cancer cells

  10. interactions between TRP1 (show PRSS1 Antibodies)-GIPC and GIPC-APPL (show APPL1 Antibodies)-AKT (show AKT1 Antibodies) provide a potential link between melanogenesis and PI3 kinase (show PIK3CA Antibodies) signaling

Mouse (Murine) GIPC PDZ Domain Containing Family, Member 1 (GIPC1) interaction partners

  1. Down-regulation of endogenous GIPC1 is sufficient to inhibit the development of eye field cells from embryonic stem cells.

  2. Higher ratios of PSD-95 (show DLG4 Antibodies)/GluN2B (show GRIN2B Antibodies) and GAIP-interacting protein C (show PROC Antibodies)-terminus (GIPC)/GluN2B (show GRIN2B Antibodies) were associated with poorer learning index scores across all ages.

  3. findings identify Gipc1 as a new interactor for Vangl2 (show VANGL2 Antibodies); show that a myosin VI (show MYO6 Antibodies)-Gipc1 protein complex can regulate Vangl2 (show VANGL2 Antibodies) traffic in heterologous cells; results indicate a broad role for Gipc1 in the development of both stereociliary bundles and cell polarization

  4. TGFbetaR3 interaction with GIPC1 is critical for regulating invasion and growth factor responsiveness in epicardial cells, and dysregulation of epicardial cell proliferation and invasion contributes to failed coronary vessel development in Tgfbr3 (show TGFBR3 Antibodies)(-/-) mice

  5. GIPC1-MyoGEF (show PLEKHG6 Antibodies) complex formation plays an important role in regulating MDA-MB-231 breast cancer cell polarization and invasion.

  6. Synectin is widely distributed in adult cells and tissues, and in the embryo apparent at day 4.5, peaks at day 12.5 and declines by day 18.5, and may be involved in mediation of outside-in signaling.

  7. Synectin selectively regulates arterial branching morphogenesis.

  8. Results define an important role for the Myo6 (show MYO6 Antibodies)-GIPC1 motor complex in presynaptic function and in BDNF (show BDNF Antibodies)-TrkB (show NTRK2 Antibodies)-mediated synaptic plasticity.

  9. a prototypical GIPC/synectin-binding receptor, revealed that deletion of its PDZ (show INADL Antibodies)-binding motif drastically reduced GIPC/synectin and myosin VI (show MYO6 Antibodies) recruitment to endocytic vesicles

  10. results confirm synectin involvement in FGF2 (show FGF2 Antibodies)-dependent signal transduction and provide insights into synectin-dependent gene expression in the endothelium

GIPC1 Antigen Profile

Protein Summary

GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008

Gene names and symbols associated with GIPC1

  • aquaporin TIP1-2 (TIP2) antibody
  • GIPC PDZ domain containing family, member 1 (gipc1) antibody
  • GIPC PDZ domain containing family, member 1 (GIPC1) antibody
  • RGS-GAIP interacting protein GIPC (LOC692815) antibody
  • rgs-gaip interacting protein gipc (AaeL_AAEL012658) antibody
  • rgs-gaip interacting protein gipc (Smp_170870) antibody
  • GIPC PDZ domain containing family, member 1 (Gipc1) antibody
  • C19orf3 antibody
  • GAMMA-TIP2 antibody
  • Gipc antibody
  • GIPC1 antibody
  • gipc3 antibody
  • GLUT1CBP antibody
  • Glut1CIP antibody
  • Hs.6454 antibody
  • IIP-1 antibody
  • kermit antibody
  • NIP antibody
  • Rgs19 antibody
  • Rgs19ip1 antibody
  • SALT-STRESS INDUCIBLE PROTEIN antibody
  • SALT-STRESS INDUCIBLE TONOPLAST INTRINSIC PROTEIN antibody
  • SEMCAP antibody
  • Semcap1 antibody
  • SITIP antibody
  • SYNECTIIN antibody
  • SYNECTIN antibody
  • TaxIP2 antibody
  • TIP-2 antibody
  • TIP1;2 antibody
  • tonoplast intrinsic protein 2 antibody
  • XGIPC antibody

Protein level used designations for GIPC1

GIPC PDZ domain containing family, member 1 , GIPC PDZ domain containing family, member 3 , regulator of G-protein signalling 19 interacting protein 1 , RGS-GAIP interacting protein GIPC , rgs-gaip interacting protein gipc , PDZ domain-containing protein GIPC1 , PDZ domain-containing protein , regulator of G-protein signaling 19-interacting protein 1 , synectin , z-synectin , developmental regulator , GAIP C-terminus-interacting protein , GLUT1 C-terminal binding protein , IGF-1 receptor interacting protein 1 , RGS-GAIP-interacting protein , RGS19-interacting protein 1 , tax interaction protein 2 , SEMCAP-1 , Tax interacting protein, clone 2 , neurophilin1-IP , regulator of G-protein signaling 19 interacting protein 1 , semaF cytoplasmic domain associated protein , semaF cytoplasmic domain-associated protein 1 , GLUT1 C-terminal-binding protein , GLUT1CBP , RGS-GAIP interacting protein C-terminus , RGS-GAIP interacting protein, C-terminus

GENE ID SPECIES
822259 Arabidopsis thaliana
496793 Xenopus (Silurana) tropicalis
717785 Macaca mulatta
747668 Pan troglodytes
692815 Bombyx mori
5576629 Aedes aegypti
8355749 Schistosoma mansoni
519617 Bos taurus
445568 Danio rerio
398204 Xenopus laevis
10755 Homo sapiens
484902 Canis lupus familiaris
67903 Mus musculus
83823 Rattus norvegicus
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