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GLB1 encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Additionally we are shipping GLB1 Kits (35) and GLB1 Proteins (18) and many more products for this protein.
Showing 10 out of 198 products:
Escherichia coli (E. coli) Polyclonal GLB1 Primary Antibody for Con, DB - ABIN1043771
Huber, Hakda, Cheng, Cupples, Edwards: Trp-999 of beta-galactosidase (Escherichia coli) is a key residue for binding, catalysis, and synthesis of allolactose, the natural lac operon inducer. in Biochemistry 2003
Show all 2 references for ABIN1043771
Escherichia coli (E. coli) Monoclonal GLB1 Primary Antibody for ICC, WB - ABIN93909
Dráber, Slavícková, Sládecek, Viklický: Monoclonal antibodies to Escherichia coli beta-galactosidase and their use for detection and purification of recombinant expression products. in Hybridoma 1992
Show all 2 references for ABIN93909
Escherichia coli (E. coli) Polyclonal GLB1 Primary Antibody for DB, IP - ABIN99522
Shearer, Fragoso, Clagett-Dame, McCaffery: Astrocytes as a regulated source of retinoic acid for the brain. in Glia 2012
Human Polyclonal GLB1 Primary Antibody for WB - ABIN1686073
Yoshida, Oshima, Shimmoto, Fukuhara, Sakuraba, Yanagisawa, Suzuki: Human beta-galactosidase gene mutations in GM1-gangliosidosis: a common mutation among Japanese adult/chronic cases. in American journal of human genetics 1991
Bacteria Polyclonal GLB1 Primary Antibody for EIA, WB - ABIN499447
Matthews: The structure of E. coli beta-galactosidase. in Comptes rendus biologies 2005
Functional loss of glucocerebrosidase (show GBA Antibodies) or beta-Gal promotes toxic conversion of alphaSyn via aberrant interactions between alphaSyn and their substrate glycolipids, leading to aggravation of alphaSyn-mediated neurodegeneration.
This study shows that moderate widespread expression of betagal in the CNS of GM1 gangliosidosis mice is sufficient to achieve significant biochemical impact with phenotypic amelioration and extension in lifespan
The study proposes an explanation for ELNR1 uncoupling based on the age-related alterations of Neu-1 (show NEU1 Antibodies) activity.
Overexpression of the novel senescence marker GLB1 in prostate cancer predicts reduced recurrence of PSA (show PLAG1 Antibodies)-expressing tumors.
Identification and analysis of GLB1 mutations in Indian patients with GM1 gangliosidosis.
We observed significant lower values of beta-galactosidase, FUC and tendency to decrease of MAN and GLU (show DCTN1 Antibodies) concentration in nasal polyps
This study analyzed patient cells with GM1 gangliosidosis and sialidosis. A novel mutation p.E186A is identified in GLB1 gene.
The activity of serum GAL (show GAL Antibodies) was significantly higher in colon cancer patients with a history of alcohol and nicotine dependence.
beta-galactosidase, considered as a senescence marker, is over-expressed only in specific subtypes of pituitary adenomas, but is also present in carcinomas considered as a group
In the serum of patients with Lyme disease, GAL (show GAL Antibodies) activity significantly increased (p = 0.029), and the activity of FUC had a tendency to increase (p = 0.153), compared to the control group.
In a Turkish population, mutations in GLB1 gene leads to severely deficient enzyme activity and result in infantile phenotype of the GM1 gangliosidosis.
Senescence-associated beta-galactosidase is present in apical vacuoles of visceral endoderm in developing mouse embryos.
We show here that mouse GLB1 has greater stability when compared to human GLB1, and that human GLB1 activity is temperature and protective-dependent on protein cathepsin A (show CTSA Antibodies), while that of mouse GLB1 is not
This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
, acid beta-galactosidase
, elastin receptor 1, 67kDa
, beta-galactosidase complex
, beta-galactosidase electrophoretic
, beta-galactosidase systemic regulator
, beta-galactosidase temporal
, lysosomal beta-galactosidase