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anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) Antibodies

GEMIN2 is part of a 500 kb inverted duplication on chromosome 5q13. Additionally we are shipping Gem (Nuclear Organelle) Associated Protein 2 Proteins (6) and Gem (Nuclear Organelle) Associated Protein 2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GEMIN2 8487 O14893
GEMIN2 66603 Q9CQQ4
GEMIN2 84404 Q9QZP1
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Top anti-Gem (Nuclear Organelle) Associated Protein 2 Antibodies at antibodies-online.com

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SIP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate Host: Rabbit  Target Name: GEMIN2  Sample Tissue: Human 721_B  Antibody Dilution: 1.0 µg/mL GEMIN2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Mouse Un-conjugated ICC, FACS, IF, IP, ELISA, WB 50 μL Log in to see 5 to 6 Days
$402.29
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Western Blot: Nuclear extract of Saos-2 cells (20 µg per lane) probed with the SIP1 antibody (mAb) at a dilution of 1 µg/ml. 100 μg Log in to see 1 to 2 Days
$466.67
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of SIP1 on a K562 cell lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti- human SIP1 antibody. Immunofluorescence staining of human intestinal smooth muscle (HISM) cells. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Sip1 AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of SIP1 in HeLa cells with SIP1 antibody at 4 μg/ml. Western blot analysis of SIP1 in HeLa cell lysate with SIP1 antibody at (A) 0.5 and (B) 1μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon labeled with Anti-Gemin 2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin-embedded rat brain labeled with Anti-Gemin 2 Polyclonal Antibody, Unconjugatedused at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), ELISA, WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of Gemin2 expression in A549 (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

GEMIN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Gem (Nuclear Organelle) Associated Protein 2 Antibodies

  1. Mouse (Murine) Monoclonal GEMIN2 Primary Antibody for ICC, FACS - ABIN108541 : Liu, Fischer, Wang, Dreyfuss: The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. in Cell 1997 (PubMed)
    Show all 8 references for ABIN108541

  2. Human Monoclonal GEMIN2 Primary Antibody for IF, IP - ABIN2668496 : Oztas, Avci, Ozcan, Sayan, Tulchinsky, Yagci: Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays. in Experimental and molecular pathology 2010 (PubMed)
    Show all 2 references for ABIN2668496

  3. Human Monoclonal GEMIN2 Primary Antibody for IF, WB - ABIN968440 : Fischer, Liu, Dreyfuss: The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis. in Cell 1997 (PubMed)
    Show all 2 references for ABIN968440

  4. Cow (Bovine) Polyclonal GEMIN2 Primary Antibody for WB - ABIN2778712 : Gregory, Bert, Paterson, Barry, Tsykin, Farshid, Vadas, Khew-Goodall, Goodall: The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. in Nature cell biology 2008 (PubMed)

More Antibodies against Gem (Nuclear Organelle) Associated Protein 2 Interaction Partners

Human Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) interaction partners

  1. Report of the first confirmed cases of Mowat Wilson syndrome in three children with the typical facial features, mental retardation, absent corpus callosum, epilepsy, and Hirschsprung's disease and novel Zeb2 (show ZEB2 Antibodies) variations on DNA analysis.

  2. Bioinformatics analyses showed that miR (show MLXIP Antibodies)-138 targeted the 3'-UTR (show UTS2R Antibodies) of ZEB2 (show ZEB2 Antibodies) mRNA to inhibit its translation. Furthermore, miR (show MLXIP Antibodies)-138 overexpression inhibited ZEB2 (show ZEB2 Antibodies)-mediated cell invasion and metastases, while miR (show MLXIP Antibodies)-138 depletion increased ZEB2 (show ZEB2 Antibodies)-mediated cell invasion and metastases in BC cells

  3. restoration of ZEB2 (show ZEB2 Antibodies) effectively reversed the Reduced expression of ZEB2 (show ZEB2 Antibodies), as well as the suppressive effects of miR200b overexpression on the proliferation.

  4. High ZEB2 (show ZEB2 Antibodies) expression is associated with clear cell kidney carcinoma.

  5. Results establish that the dowregulation of GADD45G (show GADD45G Antibodies)-SIP1 axis may contribute to cellular senescence evasion and HCC (show FAM126A Antibodies) development.

  6. MicroRNA-215 functions as a tumor suppressor and directly targets ZEB2 (show ZEB2 Antibodies) in human pancreatic cancer

  7. restoration of expression of ZEB2 (show ZEB2 Antibodies) weakened miR (show MLXIP Antibodies)-154-mediated suppression of tumor progression. miR (show MLXIP Antibodies)-154 functions as a tumor suppressor in HCC (show FAM126A Antibodies) by suppressing ZEB2 (show ZEB2 Antibodies), suggesting that miR (show MLXIP Antibodies)-154 may serve as a potential target for HCC (show FAM126A Antibodies).

  8. The authors propose that Gemin2 is a versatile hub for ribonucleoprotein exchange that functions broadly in RNA metabolism.

  9. suggest that deltaEF1 (show ZEB1 Antibodies) family proteins promote cell motility of breast cancer cells directly or indirectly through repressing expression of RGS16 (show RGS16 Antibodies)

  10. nuclear ZEB2 (show ZEB2 Antibodies) may enhance progression of EMT (show ITK Antibodies) transition and acquisition of an aggressive phenotype in ovarian cancer

Mouse (Murine) Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) interaction partners

  1. utilised a targeted screen to identify mRNA associated with SMN (show STMN1 Antibodies), Gemin2 and Gemin3 (show DDX20 Antibodies) in the cytoplasm of a human neuroblastoma (show ARHGEF16 Antibodies) cell line, SHSY5Y

  2. Gene targeting in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death (gemin2; SMN interacting protein 1)

Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with GEMIN2

  • gem (nuclear organelle) associated protein 2 (gemin2) antibody
  • gem (nuclear organelle) associated protein 2 (GEMIN2) antibody
  • gem (nuclear organelle) associated protein 2 (Gemin2) antibody
  • zinc finger E-box binding homeobox 2 (ZEB2) antibody
  • 1700012N19Rik antibody
  • HSPC082 antibody
  • SIP-1 antibody
  • Sip1 antibody
  • SIP1-delta antibody
  • SMADIP1 antibody
  • ZFHX1B antibody

Protein level used designations for GEMIN2

SMN-interacting protein 1 , Survival of motor neuron protein-interacting protein 1 , component of gems 2 , gem-associated protein 2 , gemin-2 , survival of motor neuron protein interacting protein 1 , SMN interacting protein 1-delta , survival of motor neuron protein-interacting protein 1 , survivor of motor neuron protein interacting protein 1 , SMN interacting protein-1 , SMAD interacting protein 1 , Smad-interacting protein 1 , zinc finger E-box-binding homeobox 2 , zinc finger homeobox 1b

GENE ID SPECIES
494588 Xenopus laevis
8487 Homo sapiens
510259 Bos taurus
66603 Mus musculus
84404 Rattus norvegicus
423336 Gallus gallus
610087 Canis lupus familiaris
9839 Homo sapiens
Selected quality suppliers for anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) Antibodies
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