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GEMIN2 is part of a 500 kb inverted duplication on chromosome 5q13. Additionally we are shipping Gem (Nuclear Organelle) Associated Protein 2 Proteins (6) and Gem (Nuclear Organelle) Associated Protein 2 Kits (1) and many more products for this protein.
Showing 10 out of 82 products:
Mouse (Murine) Monoclonal GEMIN2 Primary Antibody for ICC, FACS - ABIN108541
Liu, Fischer, Wang, Dreyfuss: The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. in Cell 1997
Show all 8 references for ABIN108541
Human Monoclonal GEMIN2 Primary Antibody for IF, IP - ABIN2668496
Oztas, Avci, Ozcan, Sayan, Tulchinsky, Yagci: Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays. in Experimental and molecular pathology 2010
Show all 2 references for ABIN2668496
Human Monoclonal GEMIN2 Primary Antibody for IF, WB - ABIN968440
Fischer, Liu, Dreyfuss: The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis. in Cell 1997
Show all 2 references for ABIN968440
Cow (Bovine) Polyclonal GEMIN2 Primary Antibody for WB - ABIN2778712
Gregory, Bert, Paterson, Barry, Tsykin, Farshid, Vadas, Khew-Goodall, Goodall: The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. in Nature cell biology 2008
Knockdown of ZEB2 (show ZEB2 Antibodies) can inhibit HOXB8 (show HOXB8 Antibodies)-induced migration and invasion capacity, as well as the epithelial-mesenchymal transformation in gastric cancer cells. The results showed that HOXB8 (show HOXB8 Antibodies) plays an important role in the development and metastasis of gastric carcinoma
results highlight a feedback loop between miR (show MLXIP Antibodies)-203 and ZEB2 (show ZEB2 Antibodies), which participates in the pathogenesis of lung adenocarcinoma
This is the first study claiming the association of the genetic risks of rs6755392 in the ZEB2 (show ZEB2 Antibodies) gene with schizophrenia.
Report of the first confirmed cases of Mowat Wilson syndrome in three children with the typical facial features, mental retardation, absent corpus callosum, epilepsy, and Hirschsprung's disease and novel Zeb2 (show ZEB2 Antibodies) variations on DNA analysis.
Bioinformatics analyses showed that miR (show MLXIP Antibodies)-138 targeted the 3'-UTR (show UTS2R Antibodies) of ZEB2 (show ZEB2 Antibodies) mRNA to inhibit its translation. Furthermore, miR (show MLXIP Antibodies)-138 overexpression inhibited ZEB2 (show ZEB2 Antibodies)-mediated cell invasion and metastases, while miR (show MLXIP Antibodies)-138 depletion increased ZEB2 (show ZEB2 Antibodies)-mediated cell invasion and metastases in BC cells
restoration of ZEB2 (show ZEB2 Antibodies) effectively reversed the Reduced expression of ZEB2 (show ZEB2 Antibodies), as well as the suppressive effects of miR200b overexpression on the proliferation.
High ZEB2 (show ZEB2 Antibodies) expression is associated with clear cell kidney carcinoma.
Results establish that the dowregulation of GADD45G (show GADD45G Antibodies)-SIP1 axis may contribute to cellular senescence evasion and HCC (show FAM126A Antibodies) development.
restoration of expression of ZEB2 (show ZEB2 Antibodies) weakened miR (show MLXIP Antibodies)-154-mediated suppression of tumor progression. miR (show MLXIP Antibodies)-154 functions as a tumor suppressor in HCC (show FAM126A Antibodies) by suppressing ZEB2 (show ZEB2 Antibodies), suggesting that miR (show MLXIP Antibodies)-154 may serve as a potential target for HCC (show FAM126A Antibodies).
The authors propose that Gemin2 is a versatile hub for ribonucleoprotein exchange that functions broadly in RNA metabolism.
utilised a targeted screen to identify mRNA associated with SMN (show STMN1 Antibodies), Gemin2 and Gemin3 (show DDX20 Antibodies) in the cytoplasm of a human neuroblastoma (show ARHGEF16 Antibodies) cell line, SHSY5Y
Gene targeting in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death (gemin2; SMN interacting protein 1)
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.
SMN-interacting protein 1
, Survival of motor neuron protein-interacting protein 1
, component of gems 2
, gem-associated protein 2
, survival of motor neuron protein interacting protein 1
, SMN interacting protein 1-delta
, survival of motor neuron protein-interacting protein 1
, survivor of motor neuron protein interacting protein 1
, SMN interacting protein-1
, SMAD interacting protein 1
, Smad-interacting protein 1
, zinc finger E-box-binding homeobox 2
, zinc finger homeobox 1b