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GCM1 encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). Additionally we are shipping GCM1 Proteins (3) and many more products for this protein.
Showing 10 out of 46 products:
Dog (Canine) Polyclonal GCM1 Primary Antibody for IHC, WB - ABIN2792608
Yu, Shen, Lin, Chen, Lin, Chang, Chen: GCMa regulates the syncytin-mediated trophoblastic fusion. in The Journal of biological chemistry 2002
Show all 7 Pubmed References
Dog (Canine) Polyclonal GCM1 Primary Antibody for WB - ABIN2792609
Chuang, Chang, Chang, Yao, Chen: Histone deacetylase 3 binds to and regulates the GCMa transcription factor. in Nucleic acids research 2006
Show all 2 Pubmed References
Cow (Bovine) Polyclonal GCM1 Primary Antibody for WB - ABIN2779842
Zhang, Muralimanoharan, Wortman, Mendelson: Primate-specific miR-515 family members inhibit key genes in human trophoblast differentiation and are upregulated in preeclampsia. in Proceedings of the National Academy of Sciences of the United States of America 2016
chromosomal localization of the porcine GCM1 gene and the identification and characterization of a GCM1 associated microsatellite marker [GCM1]
Identify a novel cis (show CISH Antibodies)-acting sequence (-369 to -320) at the placental growth factor (show PGF Antibodies) promoter, which was critical for mediating the basal and DLX3 (show DLX3 Antibodies)/GCM1-dependent PGF (show PGF Antibodies) promoter activities.
Twist1 (show TWIST1 Antibodies) may promote trophoblast syncytialization by regulating the expression of GCM1.
GATA3 (show GATA3 Antibodies) knockdown elevated HtrA4 (show HTRA4 Antibodies) expression in BeWo and JEG-3 trophoblast cell lines and enhanced the invasion activities of both lines. This study uncovered a new GATA3 (show GATA3 Antibodies) function in placenta as a negative regulator of GCM1 activity and trophoblastic invasion.
GLI2 (show GLI2 Antibodies) stabilized glial cell missing-a, a pivotal transcriptional factor for trophoblastic syncytialization.
Gcm1 and Fzd5 function in an evolutionary conserved positive feedback loop that regulates trophoblast differentiation and sites of chorionic branching morphogenesis.
Results suggest that caspase-14 (show CASP14 Antibodies) may interact with GCM1 to participate in syncytiotrophoblast differentiation during placental development.
study reveals a novel function for RACK1 (show GNB2L1 Antibodies) to regulate GCM1 activity and placental cell migration and invasion
GCM1-directed villous trophoblast differentiation is repressed by DREAM
c-Myc (show MYC Antibodies)-regulated members of the miR-17~92 and miR (show MLXIP Antibodies)-106a~363 clusters inhibit trophoblast differentiation by repressing GCM1 and CYP19A1 (show CYP19A1 Antibodies).
Phorbol 12-myristate 13-acetate-induced protein kinase C (show PKC Antibodies) and mitogen-activated protein kinase kinase (show MAP2K1 Antibodies)/extracellular signal regulated kinase dependent pathway enhances the degradation as well as the transcriptional activity of GCMa.
Data show that the GCM1/syncytin (show ERVW-1 Antibodies)-B pathway is significantly downregulated in the placenta of BCL9L (show BCL9L Antibodies)-deficient mice and that the fusion and differentiation of ST-II cells are blocked.
as in mice, fetoplacental vascularity increased when GCM1 protein expression decreased (R(2)=-0.45; P<0.05).
Gcm1 (glial cells missing 1) are involved in the epigenetic regulation of Hes5 (show HES5 Antibodies) transcription by DNA demethylation independently of DNA replication.
studies identify a novel function of p45NF-E2 (show NFE2 Antibodies) during placental development: in trophoblast cells, p45NF-E2 (show NFE2 Antibodies) represses Gcm1 and syncytiotrophoblast formation via acetylation
Gcm1 expression defines three stages of chorio-allantoic interaction during placental development
Brief ectopic expression of Gcm1 in mouse embryonic tail bud induces failure of the neural tube to close (spina bifida) and multiple neural tubes (diastematomyelia).
GCM domain as a new type of Zn-coordinating, sequence-specific DNA-binding domain.
mGCMa expression is primarily postnatal, arguing for a role in organ function rather than organ development
the shaping of the maternal blood spaces within the labyrinth was dependent on chorioallantoic morphogenesis and therefore disrupted in Gcm1 mutants
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.
glial cells missing homolog 1 (Drosophila)
, chorion-specific transcription factor GCMa
, glial cells missing-like protein 1
, glial cells missing homolog a
, chorion-specific transcription factor GCMa-like
, GCM motif protein 1
, Gcm 1
, Gcm a
, glial cell deficient