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anti-Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Antibodies

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. Additionally we are shipping GRLF1 Kits (4) and GRLF1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRLF1 232906 Q91YM2
GRLF1 2909 Q9NRY4
GRLF1 306400  
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Top anti-GRLF1 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells treated with EGF 200ng/ml 30', using GRF-1 (Phospho-Tyr1105) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using GRF-1 (Phospho-Tyr1105) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GRLF1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate WB Suggested Anti-GRLF1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GRF-1 (Ab-1105) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Dog Rabbit Un-conjugated WB Western blot analysis of GRLF1 (pY1087) expression in HeLa (A), mouse brain (B) whole cell lysates. 200 μL Log in to see 9 Days
$575.00
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-phospho-GRLF1(Tyr1087) Polyclonal Antibody, Unconjugated (ABIN2174954) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse kidney labeled with A Anti-phospho-GRLF1(Tyr1087) Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 14 to 21 Days
$291.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin IHC (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit HRP IHC (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details

GRLF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GRLF1 Antibodies

  1. Human Polyclonal GRLF1 Primary Antibody for IHC, ELISA - ABIN1531278 : Tikoo, Czekay, Viars, White, Heath, Arden, Maruta: p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas. in Gene 2000 (PubMed)

More Antibodies against GRLF1 Interaction Partners

Mouse (Murine) Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) interaction partners

  1. p190A acts as a modulator of Rho GTPases in a localized area around the cilia to permit the dynamic actin rearrangement required for cilia elongation.

  2. Data (including data from studies in knockout mice) suggest mechanisms involving RasGRF1 (show RASGRF1 Antibodies) exist to regulate hypothalamic-pituitary-adrenal axis in early-adolescent females; such mechanisms appear absent in younger/older female or adolescent male mice.

  3. VLDLR (show VLDLR Antibodies) requires RasGRF1 (show RASGRF1 Antibodies)/CaMKII (show CAMK2G Antibodies) to alter dendritic spine formation.

  4. Study suggests a complex role of ERK (show EPHB2 Antibodies)-dependent and Ras-GRF1 (show RASGRF1 Antibodies)-dependent signaling in corticostriatal plasticity, highlights differences between synaptic mechanisms in naive slices and dopamine-depleted preparations from L-DOPA-treated dyskinetic animals

  5. RasGrf1 (show RASGRF1 Antibodies) is an important upstream component of signal transduction pathways regulating Pttg1 (show PTTG1 Antibodies) expression and controlling beta cell development and physiological responses.

  6. CARD9 (show CARD9 Antibodies) regulates H-Ras (show HRAS Antibodies) activation by linking Ras-GRF1 (show RASGRF1 Antibodies) to H-Ras (show HRAS Antibodies), which mediates Dectin-1 (show CLEC7A Antibodies)-induced extracellular signal-regulated protein kinase (show CDK7 Antibodies) (ERK (show EPHB2 Antibodies)) activation and proinflammatory responses when stimulated by their ligands.

  7. GRF1 is expressed in new neurons when GRF1 loss begins to effect neuronal function, promoting late stages of adult neurogenesis. GRF1 is an age-dependent regulator of adult hippocampal neurogenesis and the ability to distinguish closely related contexts.

  8. Data indicate that contextual discrimination involves term potentiation (LTP (show SCP2 Antibodies)) promoted by calcium-permeable AMPA (show GRIA3 Antibodies)-type glutamate (show GRIN1 Antibodies) receptors, RAS-GRF1 (show RASGRF1 Antibodies) and p38 MAP kinase (show MAPK14 Antibodies).

  9. The cellular RacGAP activity of p190RhoGAP requires an intact polybasic region adjacent to the GAP domain whereas the RhoGAP (show ARHGAP1 Antibodies) activity is inhibited by the same domain.

  10. Ras-GRF1 (show RASGRF1 Antibodies) and -GRF2 (show RASGRF2 Antibodies) may act as adaptors that bind PLCgamma1 (show PLCG1 Antibodies) and restrict Ca2 (show CA2 Antibodies)+ signalling to the vicinity of focal adhesions, indicating a new role for these GRFs that is required for IL-1 (show IL1A Antibodies) induction of the Ras-->ERK (show EPHB2 Antibodies) pathway and MMP-3 (show MMP3 Antibodies) expression

Human Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) interaction partners

  1. these data demonstrate that a complex of p190RhoGAP-A and anillin (show ANLN Antibodies) modulates RhoA (show RHOA Antibodies)-GTP (show AK3 Antibodies) levels in the cytokinetic furrow to ensure progression of cytokinesis.

  2. These results place Blk (show BLK Antibodies) upstream of the p190RhoGAP-RhoA (show RHOA Antibodies) pathway in Galpha13 (show GNA13 Antibodies)-activated cells, overall representing an opposing signaling module during CXCL12 (show CXCL12 Antibodies)-triggered invasion.

  3. ARHGAP35 rs1052667 polymorphism was an independent prognostic factor influencing the survival of osteosarcoma.

  4. GRF-1 expression may modify osteosarcoma prognosis and may be a potential tumor therapeutic target.

  5. A ubiquitous binding partner of p190RhoGAP, p120RasGAP (RasGAP (show RASA1 Antibodies)), is expressed in much lower levels in DKO4 cells compared to DLD1, and this expression is regulated by KRAS.

  6. Overexpression of p190 (show CNTNAP1 Antibodies) mRNA associated with lung adenocarcinoma.

  7. These data suggest that the interaction of human papillomavirus E7 with p190 dysregulates this GTPase activating protein and alters the actin cytoskeleton.

  8. RhoA (show RHOA Antibodies) is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis.

  9. These results suggest that folic acid might inhibit endothelial cell migration through inhibiting the RhoA (show RHOA Antibodies) activity mediated by activating the FR/cSrc/p190RhoGAP-signaling pathway.

  10. role of the N-terminal region in signaling; Rnd1 and Rnd3 have a KERRA (Lys-Glu-Arg-Arg-Ala) sequence of amino acids in their N-terminus, which functions as the lipid raft-targeting determinant; the sequence mediates lipid raft targeting of p190 RhoGAP correlated with its activation

GRLF1 Antigen Profile

Protein Summary

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.

Gene names and symbols associated with GRLF1

  • Rho GTPase activating protein 35 (ARHGAP35) antibody
  • glucocorticoid receptor DNA binding factor 1 (Grlf1) antibody
  • RAS protein-specific guanine nucleotide-releasing factor 1 (Rasgrf1) antibody
  • Rho GTPase activating protein 35 (Arhgap35) antibody
  • 6430596G11Rik antibody
  • AI841135 antibody
  • AI844718 antibody
  • Arhgap35 antibody
  • CDC25 antibody
  • CDC25Mm antibody
  • GRF-1 antibody
  • Grf1 antibody
  • Grfbeta antibody
  • Grlf1 antibody
  • mKIAA1722 antibody
  • p190 antibody
  • p190-A antibody
  • P190A antibody
  • p190ARhoGAP antibody
  • p190RhoGAP antibody
  • p190RhoGEF antibody
  • Ras-GRF1 antibody

Protein level used designations for GRLF1

glucocorticoid receptor DNA binding factor 1 , rho GTPase-activating protein 35 , P190 RhoGAP , glucocorticoid receptor DNA-binding factor 1 , GNRP , GRF beta , Ras guanine release factor beta , guanine nucleotide releasing factor 1 , guanine nucleotide-releasing protein , ras-specific guanine nucleotide-releasing factor 1 , ras-specific nucleotide exchange factor CDC25 , glucocorticoid receptor repression factor 1 , rho GAP p190A , GAP-associated protein p190

GENE ID SPECIES
425730 Gallus gallus
540310 Bos taurus
232906 Mus musculus
19417 Mus musculus
2909 Homo sapiens
306400 Rattus norvegicus
403543 Canis lupus familiaris
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