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anti-Grainyhead-Like 3 (Drosophila) (GRHL3) Antibodies

GRHL3 encodes a member of the grainyhead family of transcription factors. Additionally we are shipping GRHL3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRHL3 57822 Q8TE85
GRHL3 230824 Q5FWH3
GRHL3 298555  
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Top anti-GRHL3 Antibodies at

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-GRHL3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate Immunohistochemistry with Placenta tissue at an antibody concentration of 5µg/ml using anti-GRHL3 antibody (ARP39489_P050) 100 μL Log in to see 2 to 3 Days
Dog Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GRHL3 / SOM Antibody (N-term) in human placenta tissue lysates (35ug/lane).This demonstrates the GRHL3 antibody detected the GRHL3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB GRHL3 Antibody (N-term)  western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the GRHL3 antibody detected the GRHL3 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC (p), WB Anti-GRHL3 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959056 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated WB Western Blot: GRHL3 Antibody [NBP2-16746] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE gel, diluted at 1:5000. 0.1 mL Log in to see 6 to 9 Days
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged GRHL3 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days

GRHL3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
, , , , ,
Mouse (Murine) , ,

Rat (Rattus) , ,

Top referenced anti-GRHL3 Antibodies

  1. Dog (Canine) Polyclonal GRHL3 Primary Antibody for IHC, WB - ABIN2781145 : Ting, Wilanowski, Cerruti, Zhao, Cunningham, Jane: The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors. in The Biochemical journal 2003 (PubMed)
    Show all 2 references for ABIN2781145

  2. Human Polyclonal GRHL3 Primary Antibody for EIA, WB - ABIN952630 : Guardiola-Serrano, Haendeler, Lukosz, Sturm, Melchner, Altschmied: Gene trapping identifies a putative tumor suppressor and a new inducer of cell migration. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN952630

  3. Human Polyclonal GRHL3 Primary Antibody for WB - ABIN2777797 : Yu, Mannik, Soto, Lin, Andersen: The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. in The EMBO journal 2009 (PubMed)
    Show all 2 references for ABIN2777797

More Antibodies against GRHL3 Interaction Partners

Human Grainyhead-Like 3 (Drosophila) (GRHL3) interaction partners

  1. GRHL3 expression may be useful as a prognostic factor.

  2. Study genotyped 10 tag SNPs covering GRHL3 and performed association analysis with nonsyndromic cleft lip with or without cleft palate in 504 cases and 455 healthy controls; preliminary results identified rs10903078, rs4638975, and a haplotype rs10903078-rs6659209 of GRHL3 that exceeded the significance threshold (p<0.05), though none survived Bonferroni correction for multiple comparisons.

  3. findings define a major role for Grhl3 in the induction of migration and invasion by the downregulation of E-cadherin (show CDH1 Antibodies) in cancer cells

  4. We discovered a genome-wide significant association with a missense variant in GRHL3 and replicated the result in an independent sample of case and control subjects. In both samples, rs41268753 conferred increased risk for cleft palate.

  5. We identified both rare dominant mutations and a common risk variant in the coding region of GRHL3 as causative in individuals with nonsyndromic cleft palate only.

  6. GRHL1 (show GRHL1 Antibodies), GRHL2 (show GRHL2 Antibodies), and GRHL3 have roles in cellular proliferation, differentiation, adhesion, and polarity and may promote cancer or be tumor suppressors [review]

  7. We defined a novel molecular signature in mammalian HNSCC, suggesting new treatment strategies targeting the GRHL3/GSK3B (show GSK3b Antibodies)/c-MYC (show MYC Antibodies) proto-oncogenic network.

  8. our results indicate predominant GRHL3 expression in breast cancers

  9. Our data demonstrated that mutations in two genes, IRF6 (show IRF6 Antibodies) and GRHL3, can lead to nearly identical phenotypes of orofacial cleft.

  10. The splice variant-derived isoforms SOM1 and SOM3 induce opposing effects in primary human endothelial cells and in a whole animal model, most likely through the induction of different target genes.

Mouse (Murine) Grainyhead-Like 3 (Drosophila) (GRHL3) interaction partners

  1. Upregulation of miR21 and repression of Grhl3 by leptin (show LEP Antibodies) mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis.

  2. This study identifies a GRHL3-regulated epidermal barrier repair pathway that suppresses disease initiation and helps resolve existing lesions in immune-mediated epidermal hyperplasia.

  3. decreased Grhl3 expression contributes to tumor progression and upregulation of the oncomir miR (show MLXIP Antibodies)-21 in squamous cell carcinoma of the skin.

  4. The developmental transcription factor Grhl3 is a potent tumor suppressor of squamous cell carcinoma in mice.

  5. Both GRHL2 (show GRHL2 Antibodies) and GRHL3 bind to and regulate expression of the wound repair gene Rho GEF (show ARHGEF2 Antibodies) 19, but regulation of the barrier forming gene, Transglutaminase 1 (TGase1 (show TGM1 Antibodies)), is unique to GRHL3.

  6. maps to Chromosome 4, 135 Mb (66 cM) from the centromere, probably not Idb3 (show ID3 Antibodies), Wnt4 (show WNT4 Antibodies), Cdc42 (show CDC42 Antibodies), perlecan (show HSPG2 Antibodies) or Grhl-3

  7. Loss of Grhl3 alone defines a distinct lower spinal closure defect, also with defective dorso-lateral hinge points formation

  8. folate deficiency caused a similar-sized, statistically significant increase in the frequency of exencephaly among both curly tail (Grhl3 mutant) embryos and background-matched embryos that are wild type for Grhl3.

  9. formation and maintenance of the epidermal barrier in mice are dependent on a mammalian homolog of grainy head, Grainy head-like 3[Grhl3]

  10. Unique role of Grhl3 in neurulation and epidermal morphogenesis.

GRHL3 Antigen Profile

Protein Summary

This gene encodes a member of the grainyhead family of transcription factors. The encoded protein may function as a transcription factor during development, and has been shown to stimulate migration of endothelial cells. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with GRHL3

  • grainyhead-like 3 (Drosophila) (GRHL3) antibody
  • grainyhead-like 3 (Drosophila) (Grhl3) antibody
  • AI561912 antibody
  • ct antibody
  • Get1 antibody
  • GRHL3 antibody
  • Som antibody
  • Tfcp2l4 antibody

Protein level used designations for GRHL3

grainyhead-like 3 (Drosophila) , sister-of-mammalian grainyhead protein , grainyhead-like protein 3 homolog , sister of mammalian grainyhead , sister-of-mammalian grainyhead , transcription factor CP2-like 4 , transcription factor hSOM1 , grainy head-like 3

419695 Gallus gallus
456630 Pan troglodytes
531906 Bos taurus
100057567 Equus caballus
57822 Homo sapiens
230824 Mus musculus
298555 Rattus norvegicus
487371 Canis lupus familiaris
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