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anti-HLA Class II DR alpha (HLA-DRA) Antibodies

HLA-DRA is one of the HLA class II alpha chain paralogues. Additionally we are shipping HLA Class II DR alpha Proteins (15) and HLA Class II DR alpha Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HLA-DRA 3122 P01903
HLA-DRA 506214  
HLA-DRA    
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Top anti-HLA Class II DR alpha Antibodies at antibodies-online.com

Showing 10 out of 134 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of HL-60 cells using HLA-DRA Antibody (C-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of HLA-DRA Antibody (C-term) in HL60 cell line lysates (35 µg/lane). HLA-DRA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Western blot analysis of HLA-DRA Antibody (N-term) in Ramos cell line lysates (35 µg/lane). HLA-DRA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB HLA-DRA Antibody  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the HLA-DRA antibody detected the HLA-DRA protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of HLA-DRA Antibody (N-term) (ABIN390770) in Ramos cell line lysates (35 µg/lane). HLA-DRA (arrow) was detected using the purified polyclonal antibody. HLA-DRA Antibody (N-term) (ABIN390770) IHC analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of HLA-DRA Antibody (C-term) (ABIN390771) in HL60 cell line lysates (35 µg/lane). HLA-DRA (arrow) was detected using the purified polyclonal antibody. HLA-DRA Antibody (C-term) (ABIN390771) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB HLA-DRA Antibody  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HLA-DRA antibody detected the HLA-DRA protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: H1299 12% SDS PAGE antibody diluted at 1:1000 IHC-P Image HLA-DRA antibody detects HLA-DRA protein at membrane on human Leukocytes in liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded Leukocytes in liver carcinoma. HLA-DRA antibody , dilution: 1:250. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Rabbit Guinea Pig Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$463.83
Details

HLA-DRA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HLA Class II DR alpha Antibodies

  1. Human Polyclonal HLA-DRA Primary Antibody for EIA, FACS - ABIN453098 : De Jager, Jia, Wang, de Bakker, Ottoboni, Aggarwal, Piccio, Raychaudhuri, Tran, Aubin, Briskin, Romano, Baranzini, McCauley, Pericak-Vance, Haines, Gibson, Naeglin, Uitdehaag, Matthews, Kappos, Polman, McArdle, Strachan, Evans, Cross, Daly, Compston, Sawc: Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. in Nature genetics 2009 (PubMed)

  2. Human Monoclonal HLA-DRA Primary Antibody for WB - ABIN659187 : Hamza, Zabetian, Tenesa, Laederach, Montimurro, Yearout, Kay, Doheny, Paschall, Pugh, Kusel, Collura, Roberts, Griffith, Samii, Scott, Nutt, Factor, Payami: Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease. in Nature genetics 2010 (PubMed)

More Antibodies against HLA Class II DR alpha Interaction Partners

Human HLA Class II DR alpha (HLA-DRA) interaction partners

  1. The frequency of CD14 (show NDUFA2 Antibodies)(+)HLA-DR-/low MDSCs could be considered as a poor prognostic predictor in small-cell lung cancer (SCLC) and the elimination of MDSCs during medical interventions may improve the prognosis of SCLC patients.

  2. This meta-analysis showed that the HLA-DRA rs3129882 A/G polymorphism was not a risk factor for Parkinson's disease in Chinese.

  3. CD14 (show NDUFA2 Antibodies)+HLA-DR(-/low) cells were significantly increased in gastric cancer tissue and were shown to have a critical role in CD4 (show CD4 Antibodies)+T-cell immunosuppression.

  4. No significant association was found for HLA-DRA/PARK18 (show EIF4G1 Antibodies) rs3129882 polymorphism and Parkinson's disease risk (meta-analysis).

  5. Increased CD14 (show NDUFA2 Antibodies)+ monocytes with loss of HLA-DR expression were seen in patients with higher stage disease, more aggressive pathology, and in relapse or refractoriness to treatment.

  6. HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping

  7. The effects of rs11248051 and rs1564282 variants of GAK (show GAK Antibodies), and the rs3129882 variant of HLA-DRA, were investigated in Parkinson's disease patients.

  8. HLA-DOA (show HLA-DOA Antibodies), HLA-DRA, and HLA-DQA1 (show HLA-DQA2 Antibodies) associated with spontaneous autoimmunity

  9. The SNP rs3129882 in intron 1 of HLA-DRA has been shown to be most robustly associated with the Parkinson's disease.

  10. suggest that binding of MAM (show ATF7IP Antibodies) to HLA-DR leads to a conformational change in MAM (show ATF7IP Antibodies) structure allowing its interaction with TLR2 (show TLR2 Antibodies) and TLR4 (show TLR4 Antibodies) and a better recognition by T cells.

Cow (Bovine) HLA Class II DR alpha (HLA-DRA) interaction partners

  1. ALOX5AP (show ALOX5AP Antibodies), CPNE3 (show CPNE3 Antibodies), IL1R2 (show IL1R2 Antibodies), IL6 (show IL6 Antibodies), TLR2 (show TLR2 Antibodies), TLR4 (show TLR4 Antibodies), and THY1 (show THY1 Antibodies) were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.

  2. Four unique SSCP patterns were detected among 384 cattle from New Zealand and sequence analysis revealed that these SSCP patterns represent 4 DRA alleles; and 3 single nucleotide polymorphisms were detected in exon 2

HLA Class II DR alpha (HLA-DRA) Antigen Profile

Protein Summary

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

Gene names and symbols associated with HLA-DRA

  • major histocompatibility complex, class II, DR alpha (hla-dra) antibody
  • major histocompatibility complex, class II, DR alpha (HLA-DRA) antibody
  • major histocompatibility complex, class II, DR alpha (MAMU-DRA) antibody
  • major histocompatibility complex, class II, DR alpha (BOLA-DRA) antibody
  • DR-alpha antibody
  • HLA-DRA antibody
  • HLA-DRA1 antibody
  • Mamu-DRA1 antibody
  • MLRW antibody

Protein level used designations for HLA-DRA

major histocompatibility complex, class II, DR alpha , HLA class II histocompatibility antigen, DR alpha chain , MHC cell surface glycoprotein , MHC class II antigen DRA , histocompatibility antigen HLA-DR alpha , MHC class II DRA , MHC class II antigen , BoLA-DR-alpha

GENE ID SPECIES
495177 Xenopus laevis
3122 Homo sapiens
100187587 Macaca mulatta
506214 Bos taurus
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