HLA-DRA antibody (C-Term)

Catalog No. ABIN390771

The Rabbit Polyclonal anti-HLA-DRA antibody (Clone RB19527) (ABIN390771) specifically detects HLA-DRA in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for HLA-DRA antibody (C-Term) (ABIN390771)

Target: HLA-DRA (HLA Class II DR alpha (HLA-DRA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DRA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB19527

Product Details anti-HLA-DRA Antibody

Binding Specificity: AA 149-177, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HLA-DRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the C-terminal region of human HLA-DRA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HLA-DRA

Target: HLA-DRA (HLA Class II DR alpha (HLA-DRA))

Alternative Name: HLA-DRA

Background: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages).

Molecular Weight: 28607

Gene ID: 3122

NCBI Accession: NP_061984

UniProt: P01903

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response