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HLA-DRA antibody

HLA-DRA Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7244882
  • Target See all HLA-DRA Antibodies
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Reactivity
    • 89
    • 17
    • 10
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 56
    • 48
    • 1
    • 1
    Rabbit
    Clonality
    • 56
    • 50
    Polyclonal
    Conjugate
    • 54
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This HLA-DRA antibody is un-conjugated
    Application
    • 49
    • 49
    • 35
    • 32
    • 17
    • 12
    • 11
    • 10
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human HLA-DRA
    Isotype
    IgG
    Top Product
    Discover our top product HLA-DRA Primary Antibody
  • Application Notes
    IHC 1:50-1:100, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.9 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Alternative Name
    HLA-DRA (HLA-DRA Products)
    Synonyms
    HLA-DRA1 antibody, MLRW antibody, DR-alpha antibody, HLA-DRA antibody, Mamu-DRA1 antibody, major histocompatibility complex, class II, DR alpha L homeolog antibody, major histocompatibility complex, class II, DR alpha antibody, hla-dra.L antibody, HLA-DRA antibody, MAMU-DRA antibody, BOLA-DRA antibody
    Background
    HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
    UniProt
    P01903
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events
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