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anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) Antibodies

HSPD1 encodes a member of the chaperonin family. Additionally we are shipping Heat Shock 60kDa Protein 1 (Chaperonin) Kits (65) and Heat Shock 60kDa Protein 1 (Chaperonin) Proteins (29) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPD1 3329 P10809
Anti-Mouse HSPD1 HSPD1 15510 P63038
Anti-Rat HSPD1 HSPD1 63868 P63039
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Top anti-Heat Shock 60kDa Protein 1 (Chaperonin) Antibodies at antibodies-online.com

Showing 10 out of 451 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Mouse Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of anti-HSPD1 Antibody (Center) (ABIN389380) in A2058 cell line lysates (35 µg/lane). HSPD1(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Mouse Un-conjugated FACS, IP, IHC, ELISA, WB Hsp60 (LK 1), cell line mix. 50 μg Log in to see 3 to 4 Days
$183.70
Details
Human Mouse Un-conjugated BI, WB Western blot analysis of Hsp60 on a Jurkat lysate (ABIN968537). Lane 1: 1:5000, lane 2: 1:10000, lane 3: 1:20000 dilution of the Hsp60 antibody. Immunofluorescent staining of A549 (ATCC CCL-185) cells. Cells were seeded in a 96 well imaging plate at ~ 10 000 cells per well. After overnight incubation, cells were stained using the Triton™ X-100 perm protocol and the anti-Hsp60 antibody. The second step reagent was Alexa Fluor 488 goat anti mouse Ig (Invitrogen). The image was taken on a BD Pathway™ 855 Bioimager using a 20x objective. This antibody also stained U-2 OS (ATCC HTB-96) and HeLa (ATCC CCL-2) cells using both the Triton™ X-100 and alcohol perm protocols. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Bacteria Mouse Un-conjugated FACS, IHC (fro), WB Immunohistochemistry analysis of Listeria infected mice spleens 6 days after infection with L-monocytogenes using AM03145PU (Clone LK2). Hsp60 visualized using AM03145PU (Clone LK2), tested on Human colon cancer cells. 50 μg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti CYP5A1/Thromboxane synthase Polyclonal Antibody, Unconjugated (ABIN726080) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti HSP60 Polyclonal Antibody, Unconjugated (ABIN726080) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of Hela cells using HSP60 mouse mAb (green) and negative control (purple) . 100 μL Log in to see 3 to 4 Days
$430.10
Details

HSPD1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Heat Shock 60kDa Protein 1 (Chaperonin) Antibodies

  1. Chicken Monoclonal HSPD1 Primary Antibody for FACS, IP - ABIN361784 : Verda, Kim, Ikehara, Statkute, Bronesky, Petrenko, Oyama, He, Link, Vahanian, Burt: Hematopoietic mixed chimerism derived from allogeneic embryonic stem cells prevents autoimmune diabetes mellitus in NOD mice. in Stem cells (Dayton, Ohio) 2008 (PubMed)
    Show all 17 references for ABIN361784

  2. Bacteria Monoclonal HSPD1 Primary Antibody for FACS, IHC (fro) - ABIN263949 : Hartl: Molecular chaperones in cellular protein folding. in Nature 1996 (PubMed)
    Show all 11 references for ABIN263949

  3. Human Monoclonal HSPD1 Primary Antibody for BI, WB - ABIN968590 : Ohashi, Burkart, Flohé, Kolb: Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 5 references for ABIN968590

  4. Chicken Monoclonal HSPD1 Primary Antibody for IHC (p), IP - ABIN1107605 : Hansen, Bross, Westergaard, Nielsen, Eiberg, Børglum, Mogensen, Kristiansen, Bolund, Gregersen: Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter. in Human genetics 2002 (PubMed)
    Show all 3 references for ABIN1107605

  5. Human Monoclonal HSPD1 Primary Antibody for EIA, IHC (p) - ABIN263916 : Cheng, Hartl, Horwich: The mitochondrial chaperonin hsp60 is required for its own assembly. in Nature 1991 (PubMed)
    Show all 2 references for ABIN263916

  6. Human Monoclonal HSPD1 Primary Antibody for ICC, FACS - ABIN969200 : López-Hoyos, Alvarez, Ruiz Soto, Blanco, José Bartolomé, Martínez-Taboada: Serum levels of antibodies to Chlamydia pneumoniae and human HSP60 in giant cell arteritis patients. in Clinical and experimental rheumatology 2009 (PubMed)
    Show all 2 references for ABIN969200

  7. Human Polyclonal HSPD1 Primary Antibody for IF, WB - ABIN389380 : Venner, Singh, Gupta: Nucleotide sequences and novel structural features of human and Chinese hamster hsp60 (chaperonin) gene families. in DNA and cell biology 1991 (PubMed)
    Show all 2 references for ABIN389380

  8. Human Polyclonal HSPD1 Primary Antibody for IF (p), IHC (p) - ABIN726080 : Kengkoom, Ampawong: Chronic ingestion of high dosed Phikud Navakot extraction induces mesangiolysis in rats with alteration of AQP1 and Hsp60 expressions. in BioMed research international 2015 (PubMed)
    Show all 2 references for ABIN726080

  9. Cow (Bovine) Polyclonal HSPD1 Primary Antibody for WB - ABIN2792215 : Hewamadduma, Kirby, Kershaw, Martindale, Dalton, McDermott, Shaw: HSP60 is a rare cause of hereditary spastic paraparesis, but may act as a genetic modifier. in Neurology 2008 (PubMed)

More Antibodies against Heat Shock 60kDa Protein 1 (Chaperonin) Interaction Partners

Fruit Fly (Drosophila melanogaster) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Expression of HSP60A is post-transcriptionally regulated in a highly dynamic pattern during embryogenesis, even under heat-shock conditions. In contrast, in very stressful situations, its expression is upregulated transcriptionally over the entire embryo.

Zebrafish Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Heat-shock protein 60 is required for blastema formation and maintenance during regeneration.

Human Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Data indicate that on addition of the heat-shock proteins GroEL (show GroEL Antibodies)-GroES (show HSPE1 Antibodies) molecular chaperone (show HSP90AA1 Antibodies) system, the folding of the nascent chemokine receptor (show CCR1 Antibodies) type 5 (CCR5 (show CCR5 Antibodies)) was significantly enhanced.

  2. The data show that immunohistochemistry for CD1a (show CD1A Antibodies) and Hsp60 can be of help in differential diagnosis between Keratoacantomas and well-differentiated forms of squamous cell carcinomas.

  3. Anti-citrullinated protein antibodies promote apoptosis of mature human osteoblasts via cell-surface binding to citrullinated heat shock protein 60.

  4. Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 (show TLR4 Antibodies) and ERK MAPK (show MAPK1 Antibodies) activation

  5. Studies show that contrary to its role as a target for pathogenic autoimmune inflammatory processes, heat-shock protein 60 (HSP60) has been shown to activate immunoregulatory pathways that may lead to suppression of these diseases.

  6. Biochemical and genetic data demonstrate that FUS (show FUS Antibodies) interacts with a mitochondrial chaperonin, HSP60, and that FUS (show FUS Antibodies) translocation to mitochondria is, at least in part, mediated by HSP60

  7. exposure of human promyelocytic HL-60 cells to a nontoxic concentration (10 muM) of 4-hydroxy-2-nonenal (HNE (show ELANE Antibodies)) yielded a HSP60 modified with HNE (show ELANE Antibodies).

  8. HSP60 overexpression was associated with the disease progression and prognosis in gastric cancer, and its expression significantly correlated with the expression of MMP-9 (show MMP9 Antibodies).

  9. Hsp60 is increased in both animals and patients with TLE in affected tissues, and in plasma in response to epileptic seizures, and point to it as biomarker of hippocampal stress potentially useful for diagnosis and patient management.

  10. no significant relationship between anti-hsp60 antibodies and serological markers of infection was observed, which may only indicate an indirect role of infection in the assessment of breaking the immunological tolerance against autologous HSPs

Pig (Porcine) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. Wild type HSP60 displayed a heptameric single-ring structure in the absence of ATP. In contrast, HSP60 formed mainly a "football-type" complex with HSP10 (show HSPE1 Antibodies) in the presence of ATP and mediated the refolding of denatured substrate protein.

  2. These results indicate that different tissues had different sensitivities to transport stress, possibly resulting in varying levels of cytoprotection by Hsp60 in the different tissues.

Cow (Bovine) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. This paper reports the localization of both GRP78 (show HSPA5 Antibodies) and HSP60 on the luminal/apical surface of oviduct epithelial cells, their binding to spermatozoa, and the presence of endogenous HSP60 in the sperm midpiece.

Mouse (Murine) Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) interaction partners

  1. neonatal heart failure through HSP60 induction likely involves developmental defects and excessive apoptosis

  2. Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 (show TLR4 Antibodies) and ERK MAPK (show MAPK1 Antibodies) activation

  3. TLR4 (show TLR4 Antibodies) mediates HSP60-associated apoptosis and that HSP60 has an important role in cardiac myocyte injury, both apoptotic and necrotic.

  4. a direct toxic effect of heat shock protein 60 towards neurons and oligodendrocytes in the CNS involving Toll (show TLR4 Antibodies)-like receptor4 and MyD88 (show MYD88 Antibodies) pathways

  5. Dietary wolfberry elevated the xanthophyll concentrations and enhanced expression of BCO2 (show BCO2 Antibodies) and heat shock protein 60, activated AMPKalpha2 (show PRKAA2 Antibodies), potentiated mitophagy and mitochondrial biogenesis and enhanced lipid oxidation and secretion in the liver of mice.

  6. It is concluded that nasal administration of HSP60 can inhibit atherosclerotic formation through immune tolerance which is established by Tregs depending on the induction of anti-inflammatory cytokine TGF-beta (show TGFB1 Antibodies).

  7. MnSOD (show SOD2 Antibodies) is a substrate of the Hsp60 folding machinery.

  8. In type 2 diabetes, there is hypothalamic insulin (show INS Antibodies) resistance and mitochondrial dysfunction due to downregulation of the mitochondrial chaperone HSP60. HSP60 reduction was due to a lack of proper leptin (show LEP Antibodies) signaling and was restored by leptin (show LEP Antibodies) treatment.

  9. Data indicate that HMGB1 (show HMGB1 Antibodies) and HSP60 are expressed in a Myd88 (show MYD88 Antibodies) dependent manner.

  10. a novel interaction between APP (show APP Antibodies) and HSP60, which accounts for its translocation to the mitochondria.

Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) Antigen Profile

Protein Summary

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Gene names and symbols associated with HSPD1

  • Heat shock protein 60 (Hsp60) antibody
  • heat shock 60kDa protein 1 (chaperonin) (HSPD1) antibody
  • heat shock 60kDa protein 1 (chaperonin) (hspd1) antibody
  • chaperone ATPase HSP60 (HSP60) antibody
  • molecular chaperone GroEL (groEL) antibody
  • chaperonin GroEL (hsp60) antibody
  • molecular chaperone GroEL (groEl) antibody
  • chaperonin GroEL (groEL) antibody
  • mitochondrial chaperonin (HSP60) antibody
  • heat shock protein 60 (hsp60) antibody
  • heat shock 60kD protein 1 (chaperonin) (hspd1) antibody
  • heat shock protein 1 (chaperonin) (Hspd1) antibody
  • 12 antibody
  • 60kDa antibody
  • BP5 antibody
  • cb863 antibody
  • CG12101 antibody
  • chaperonin antibody
  • CPN60 antibody
  • crpA antibody
  • d-hsp60 antibody
  • Dmel\\CG12101 antibody
  • Dmhsp60 antibody
  • fa04a05 antibody
  • fb22d10 antibody
  • fi27b05 antibody
  • G62 antibody
  • GROEL antibody
  • groL antibody
  • HLD4 antibody
  • HSP-60 antibody
  • Hsp60 antibody
  • hsp60A antibody
  • HSP65 antibody
  • HSPD1 antibody
  • Hspd1-30p antibody
  • HuCHA60 antibody
  • id:ibd2197 antibody
  • IEF16 antibody
  • l(1)10Ac antibody
  • l(1)BP5 antibody
  • l(1)dp025 antibody
  • l(1)G8 antibody
  • l(1)HM21 antibody
  • l(1)L12 antibody
  • MIF4 antibody
  • Mmp-P1 antibody
  • MNA2 antibody
  • mopA antibody
  • sb:cb144 antibody
  • SPG13 antibody
  • SSP 7506 antibody
  • wu:fa04a05 antibody
  • wu:fb22d10 antibody
  • wu:fi04a12 antibody
  • wu:fi27b05 antibody

Protein level used designations for HSPD1

60-kDa heat shock protein, mitochondrial , CG12101-PA , CG12101-PB , Hsp 60 , Hsp60-PA , Hsp60-PB , heat shock protein 60 , heat shock protein 60 kDa , lethal(1)10Ac , mitochondrial matrix protein P1 , 60 kDa heat shock protein, mitochondrial , chaperonin , heat shock 60kDa protein 1 (chaperonin) , 60 kDa heat shock protein, mitochondrial-like , chaperonin GroEL , mitochondrial chaperonin , hsp60 , nbl , no blastema , 60 kDa chaperonin , P60 lymphocyte protein , chaperonin 60 , heat shock protein 65 , short heat shock protein 60 Hsp60s1 , CPN60 , HSP-60 , heat shock 60 kDa protein 1 , mitochondrial heat shock 60 kDa protein 1 , HSP-65 , heat shock protein, 60 kDa , heat shock 60kD protein 1 (chaperonin) , heat shock 60kDa protein 1 , heat shock protein 60 (liver)

GENE ID SPECIES
32045 Drosophila melanogaster
459852 Pan troglodytes
693438 Macaca mulatta
100124945 Xenopus (Silurana) tropicalis
100349912 Oryctolagus cuniculus
100414401 Callithrix jacchus
100604694 Nomascus leucogenys
850963 Saccharomyces cerevisiae S288c
1173196 Yersinia pestis CO92
2761905 Methanococcus maripaludis S2
2780418 Candidatus Protochlamydia amoebophila UWE25
2859943 Staphylococcus aureus subsp. aureus MRSA252
2955745 Yersinia pseudotuberculosis IP 32953
4714365 Yersinia enterocolitica subsp. enterocolitica 8081
7442965 Thalassiosira pseudonana CCMP1335
100136430 Salmo salar
698024 Macaca mulatta
100477321 Ailuropoda melanoleuca
282676 Danio rerio
3329 Homo sapiens
424059 Gallus gallus
492279 Sus scrofa
511913 Bos taurus
478854 Canis lupus familiaris
399217 Xenopus laevis
100174117 Pongo abelii
15510 Mus musculus
63868 Rattus norvegicus
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