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The protein encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin. Additionally we are shipping HMGN1 Kits (27) and HMGN1 Proteins (15) and many more products for this protein.
Showing 10 out of 99 products:
Human Polyclonal HMGN1 Primary Antibody for IHC (p), WB - ABIN658140
Rattner, Yusufzai, Kadonaga: HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility. in Molecular cell 2009
Show all 4 references for ABIN658140
Chicken Polyclonal HMGN1 Primary Antibody for EIA, IHC (p) - ABIN401321
Landsman, McBride, Soares, Crippa, Srikantha, Bustin: Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family. in The Journal of biological chemistry 1989
Show all 2 references for ABIN401321
Cow (Bovine) Polyclonal HMGN1 Primary Antibody for IHC, WB - ABIN2779758
Zhu, Hansen: HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors. in Molecular and cellular biology 2007
Human Polyclonal HMGN1 Primary Antibody for IF, ELISA - ABIN1532678
Hattori, Fujiyama, Taylor, Watanabe, Yada, Park, Toyoda, Ishii, Totoki, Choi, Groner, Soeda, Ohki, Takagi, Sakaki, Taudien, Blechschmidt, Polley, Menzel, Delabar, Kumpf, Lehmann, Patterson, Reichwald et al.: The DNA sequence of human chromosome 21. ... in Nature 2000
Suggest Hmgn1/Cebpb (show CEBPB Antibodies) signaling may play an important role during mouse decidualization.
our findings show that HMGN1 contributes to antitumor immunity and it may offer an effective adjuvant to heighten responses to cancer vaccines.
in mice, loss of HMGN1 leads to transcription changes that accelerate the progression of DEN-induced hepatocarcinogenesis, without affecting the type of tumors or the final total tumor burden of these mice.
HMGN1 is a nucleosome remodeling protein encoded on chromosome 21q22 that suppresses H3K27me3 and promotes both B cell proliferation in vitro and B-ALL in vivo
HMGN1 binds to CpG island-containing promoters and affects the organization of nucleosomes, DNase I (show DNASE1 Antibodies) hypersensitivity, and the transcriptional profile of mouse embryonic stem cells and neural progenitors.
Phenotypic analysis of Hmgn1(tm1/tm1 (show TPM2 Antibodies)), Hmgn3 (show HMGN3 Antibodies)(tm1/tm1 (show TPM2 Antibodies)), and Hmgn5 (show HMGN5 Antibodies)(tm1/tm1 (show TPM2 Antibodies)) mice and their wild type littermates with a battery of standardized tests uncovered variant-specific abnormalities.
a regulatory role for HMGN1 in PARP-1 (show PARP1 Antibodies) activation.
extracellular HMGN1 acts as a novel alarmin critical for LPS (show TLR4 Antibodies)-induced development of innate and adaptive immune responses.
HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2 (show MECP2 Antibodies)) in mouse and human, and affects the behavior of mice
Regulation of Hmgn1 and Fgf18 (show FGF18 Antibodies) at the digit-interdigit junction suggests retinoic acid controls tissue remodeling as well as apoptosis.
RNA-seq evidence of biallelic expression of HMGN1 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of HMGN1 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (show WRB Antibodies) differentially methylated region (DMR (show WDR20 Antibodies)) in disomic controls or trisomy (Down syndrome) individuals.
HMGN1 can serve as a useful clinical parameter for evaluating disease progression and predicting the outcomes for early-stage patients with non-small cell lung cancer .
nucleosome binding protein HMGN1 as a new PCNA (show PCNA Antibodies)-interacting protein that enhances the binding of PCNA (show PCNA Antibodies) to chromatin
extracellular HMGN1 acts as a novel alarmin critical for LPS (show IRF6 Antibodies)-induced development of innate and adaptive immune responses.
HMGN1 is not randomly distributed throughout the genome. Instead, the protein preferentially localizes to DNase I (show DNASE1 Antibodies) hypersensitive (HS) sites, promoters, functional enhancers, and transcription factor binding sites.
Results show that four serine residues, i.e., Ser6, Ser85, Ser88, and Ser98, can be phosphorylated in high mobility group (show SSRP1 Antibodies) N1 (HMGN1).
HMGN1 optimizes the cellular response to ionizing radiation and to other tumorigenic events; therefore, loss of this protein increases the tumor burden in mice.
SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) functions independently of HMGN1
Five serine residues, i.e., Ser6, Ser7, Ser85, Ser88, and Ser98, in HMGN1 can be phosphorylated by the kinase in vitro, and Ser6, Ser7, and Ser85 were new sites among these five sites.
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.
high-mobility group nucleosome binding domain 1 b
, high-mobility group nucleosome binding domain 1
, non-histone chromosomal protein HMG-14
, high mobility group nucleosome-binding domain-containing protein 1
, high mobility group protein 14
, high-mobility group nucleosome-binding domain-containing protein 1
, HMG-14 protein
, non-histone chromosomal protein HMG-14B
, high-mobility group (nonhistone chromosomal) protein 14
, high-mobility group nucleosome binding 1
, nonhistone chromosomal protein HMG-14