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binds the zinc finger region of the androgen receptor; may play a role in regulation of androgen receptor function. Additionally we are shipping Homeodomain Interacting Protein Kinase 3 Proteins (5) and many more products for this protein.
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Human Polyclonal HIPK3 Primary Antibody for IHC (p), WB - ABIN391779
Tiefenbach, Moll, Nelson, Hu, Baev, Kislinger, Krause: A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. in PLoS ONE 2010
Show all 4 references for ABIN391779
circHIPK3 directly binds to miR (show MLXIP Antibodies)-124 and inhibits miR (show MLXIP Antibodies)-124 activity and cell cycle progression.
Analysis of these mutants revealed that HIPK1 (show HIPK1 Antibodies), HIPK2 (show HIPK2 Antibodies) and HIPK3 but not HIPK4 (show HIPK4 Antibodies) are capable of autophosphorylating on other tyrosines
JNK (show MAPK8 Antibodies) regulates the expression of HIPK3 in prostate cancer cells, which leads to increased resistance to Fas receptor (show FAS Antibodies)-mediated apoptosis by reducing the interaction between FADD (show FADD Antibodies) and caspase-8 (show CASP8 Antibodies)
This finding has linked three common factors, HIPK3, JNK (show MAPK8 Antibodies), and c-Jun (show JUN Antibodies), to the cAMP signaling pathway leading to increased steroidogenic gene expression
Depletion of HIPK3 impairs insulin (show INS Antibodies) secretion and glucose tolerance. Decreased levels of HIPK3 may play a substantial role in the pathogenesis of type 2 diabetes.
Runx2 (show RUNX2 Antibodies) trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3.(
binds the zinc finger region of the androgen receptor\; may play a role in regulation of androgen receptor function
homeodomain interacting protein kinase 3
, homeodomain-interacting protein kinase 3-like
, androgen receptor-interacting nuclear protein kinase
, fas-interacting serine/threonine-protein kinase
, homeodomain-interacting protein kinase 3
, homolog of protein kinase YAK1
, HCMV-interacting protein
, nuclear body-associated kinase 3
, nuclear serine/threonine protein kinase