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Hypoxanthine phosphoribosyltransferase 1 Proteins (HPRT1)

The protein encoded by HPRT1 is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. Additionally we are shipping HPRT1 Antibodies (147) and HPRT1 Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HPRT1 15452 P00493
HPRT1 3251 P00492
HPRT1 24465 P27605
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Top HPRT1 Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Crithidia fasciculata His tag   1 mg Log in to see 56 to 66 Days
$2,509.83
Details
Yeast REACT_Leishmania donovani His tag   1 mg Log in to see 56 to 66 Days
$2,520.83
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,539.17
Details
Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$2,539.17
Details

HPRT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

Top referenced HPRT1 Proteins

  1. Human HPRT1 Protein expressed in Escherichia coli (E. coli) - ABIN667016 : Hladnik, Nyhan, Bertelli: Variable expression of HPRT deficiency in 5 members of a family with the same mutation. in Archives of neurology 2008 (PubMed)
    Show all 2 references for ABIN667016

More Proteins for Hypoxanthine phosphoribosyltransferase 1 (HPRT1) Interaction Partners

Mouse (Murine) Hypoxanthine phosphoribosyltransferase 1 (HPRT1) interaction partners

  1. In the HGprt-deficient mouse model, stains for tyrosine hydroxylase (TH (show TH Proteins)) reveal no obvious loss of midbrain dopamine neurons, but quantitative immunoblots reveal reduced TH expression in the striatum.

  2. HPRT-deficiency alters cAMP/PKA signaling pathway, which is in part due to the increased of PDE10A (show PDE10A Proteins) expression and activi

  3. Hprt is proposed as a reference gene for analysis of gene expression in neural developmental issues of the murine neocortex.

  4. Data indicate that Ubc (show UBA52 Proteins) and Ywhaz (show YWHAZ Proteins) were best correlated for cB cells and lymphocytes, whereas Ubc (show UBA52 Proteins) and Gapdh (show GAPDH Proteins) were the best combination for non-B cells, and Actb (show ACTB Proteins) and Hprt1 were the least stably expressed genes for B cells and non-B cell.

  5. Data indicate that Hprt, Rpl13a (show RPL13A Proteins) and Tpt1 (show TPT1 Proteins) are a set of stably expressed reference genes for accurate gene expression normalization in myocardial infarction studies in mice.

  6. These results demonstrate that PRTFDC1 (show PRTFDC1 Proteins) is a genetic modifier of HPRT-deficiency in the mouse.

  7. ionizing radiation-induced mutant phenotype plasticity is not dependent on DNA methylation (show HELLS Proteins) of the hypoxanthine phosphoribosyl transferase gene in mouse FM3A cells

  8. the characterization of Hprt mutations in vivo in Blm hypomorphic mice

  9. Hprt mutant frequencies were determined in aging male rats on caloric restriction diets.

  10. Study suggests that mice chronically treated with azathioprine have elevated Hprt mutations due to clonal amplification of Hprt mutants.

Human Hypoxanthine phosphoribosyltransferase 1 (HPRT1) interaction partners

  1. Pseudogene-free amplification of HPRT1 in quantitative reverse transcriptase polymerase chain reaction.

  2. HPRT gene mutation assay demonstrated that surface chemical composition plays a significant role in silver nanoparticle toxicity.

  3. Lesch-Nyhan Syndrome in a Family with a Deletion Followed by an Insertion within the HPRT1 Gene

  4. A highly significant correlation between six metabolites and the HGprt deficiency was established, each of them providing an easily measurable marker of the disease.

  5. HPRT mutations are not increased by systemic depleted uranium exposure.

  6. 13 novel mutations in Saudi Arabian HPRT-related hyperuricemia patients manifesting different levels of uric acid.

  7. HPRT1 mutations in new Japanese families and PRPP concentration

  8. In the study presented here, for the first time T-705/favipiravir absolutely depends on the cellular HGPRT enzyme to exert its anti-influenza virus activity in mammalian cells.

  9. Molecular genetic testing revealed a new frameshift mutation in the HPRT1 gene causing Lesch-Nyhan syndrome in an Indian family.

  10. study reports three novel independent mutations in the coding region of HPRT gene: exon 3: c.141delA, p.D47fs53X; exon 5: c.400G>A, p.E134K; exon 7: c.499A>G, p.R167G from three Lesch-Nyhan syndrome affected male patients

Cow (Bovine) Hypoxanthine phosphoribosyltransferase 1 (HPRT1) interaction partners

  1. levels of G6PD (show G6PD Proteins) and HPRT RNA were higher in female morulae and blastocysts than in males

HPRT1 Protein Profile

Protein Summary

The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

Gene names and symbols associated with HPRT1

  • hypoxanthine guanine phosphoribosyl transferase (Hprt)
  • hypoxanthine phosphoribosyltransferase 1 (hprt1)
  • hypoxanthine phosphoribosyltransferase 1 (HPRT1)
  • hypoxanthine phosphoribosyltransferase 1 (Hprt1)
  • C81579 protein
  • HGPRT protein
  • Hgprtase protein
  • HPGRT protein
  • Hprt protein
  • Hprt1 protein
  • id:ibd1344 protein
  • id:ibd5108 protein
  • prtfdc1 protein
  • wu:fc10g09 protein
  • zgc:56221 protein
  • zgc:86608 protein

Protein level used designations for HPRT1

HGPRT , HGPRTase , HPRT B , hypoxanthine guanine phosphoribosyl transferase 1 , hypoxanthine-guanine phosphoribosyltransferase , phosphoribosyl transferase domain containing 1 , hypoxanthine guanine phosphoribosyl transferase , hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) , hypoxanthine-guanine phosphoribosyltransferase 1 , hypoxanthine phosphoribosyltransferase 1 [(Lesch-Nyhan syndrome) , hypoxanthine phosphoribosyl transferase

GENE ID SPECIES
15452 Mus musculus
406259 Danio rerio
779138 Xenopus laevis
395653 Gallus gallus
3251 Homo sapiens
442945 Canis lupus familiaris
397351 Sus scrofa
281229 Bos taurus
100126071 Oryctolagus cuniculus
24465 Rattus norvegicus
735894 Pan troglodytes
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