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anti-IQ Motif and Sec7 Domain 1 (IQSEC1) Antibodies

In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.. Additionally we are shipping IQSEC1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IQSEC1 9922 Q6DN90
IQSEC1 232227 Q8R0S2
IQSEC1 686590  
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Top anti-IQSEC1 Antibodies at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p) Anti-IQSEC1 antibody IHC staining of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1102601 dilution 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB   50 μg Log in to see 11 to 13 Days
$478.80
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated IHC   50 μg Log in to see 11 to 16 Days
$658.43
Details
Human Rabbit Un-conjugated IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated   50 μL Log in to see 9 to 14 Days
$417.00
Details

IQSEC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,


Mouse (Murine)


Rat (Rattus)


More Antibodies against IQSEC1 Interaction Partners

Human IQ Motif and Sec7 Domain 1 (IQSEC1) interaction partners

  1. Brag2 is essential for developmental and pathological angiogenesis by promoting endothelial cell sprouting through regulation of adhesion by beta1-integrin internalization and link for the first time the process of beta1-integrin endocytosis with angiogenesis.

  2. The EGFR (show EGFR Antibodies)-GEP100-Arf6 (show ARF6 Antibodies) axis affected the prognosis of patients with primary lung adenocarcinoma.

  3. Data show that co-overexpression of GEP100 and AMAP1 (ASAP1 (show ASAP1 Antibodies)) correlates with rapidity of the local recurrence.

  4. GEP100 regulates an Arf6 (show ARF6 Antibodies)/ERK (show EPHB2 Antibodies)/uPAR (show PLAUR Antibodies) signaling cascade in EGF (show EGF Antibodies)-induced breast cancer cell invasion.

  5. GEP100 plays a significant role in pancreatic cancer invasion through regulating the expression of E-cadherin (show CDH1 Antibodies) and the process of mesenchymal to epithelial transition (MET).

  6. BRAG2 acts at clathrin-coated pits to promote integrin internalization by activating Arf5 and suggest a previously unrecognized role for Arf5 in clathrin-mediated endocytosis of specific cargoes.

  7. GEP100/Arf6 is required for epidermal growth factor-induced ERK/Rac1 signaling and cell migration in human hepatoma HepG2 cells.

  8. The PH domain and the interdomain linker of Brag2 may be targets for selectively regulating the activity of Brag2.

  9. Data suggest that GEP100-Arf6 (show ARF6 Antibodies)-AMAP1 (show ASAP1 Antibodies)-cortactin (show CTTN Antibodies) pathway, activated by VEGFR2 (show KDR Antibodies), appears to be common in angiogenesis and cancer invasion and metastasis, and provides their new therapeutic targets.

  10. Cinical study indicates that co-overexpression of Her2 (show ERBB2 Antibodies) with GEP100 in primary lung adenocarcinomas of patients is correlated with the presence of their node-metastasis with a statistical significance.

Mouse (Murine) IQ Motif and Sec7 Domain 1 (IQSEC1) interaction partners

  1. BRAG2 localized to postsynaptic processes at bipolar dyads, while BRAG3 (show IQSEC3 Antibodies) localized to postsynaptic components at conventional synapses in mouse retina

IQSEC1 Antigen Profile

Protein Summary

In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.

Gene names and symbols associated with IQSEC1

  • IQ motif and Sec7 domain 1 (IQSEC1) antibody
  • IQ motif and Sec7 domain 1 (Iqsec1) antibody
  • ARF-GEP100 antibody
  • ARFGEP100 antibody
  • AW561907 antibody
  • BC026481 antibody
  • BRAG2 antibody
  • cI-43 antibody
  • D6Ertd349e antibody
  • GEP100 antibody
  • mKIAA0763 antibody

Protein level used designations for IQSEC1

ADP-ribosylation factors guanine nucleotide-exchange protein 100 , ADP-ribosylation factors guanine nucleotide-exchange protein 2 , IQ motif and SEC7 domain-containing protein 1 , brefeldin A-resistant ARF-GEF2 , brefeldin-resistant Arf-GEF 2 protein

GENE ID SPECIES
9922 Homo sapiens
232227 Mus musculus
686590 Rattus norvegicus
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