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anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) Antibodies

IDO1 encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. Additionally we are shipping Indoleamine 2,3-Dioxygenase 1 Kits (16) and Indoleamine 2,3-Dioxygenase 1 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IDO1 3620 P14902
IDO1 15930 P28776
IDO1 66029 Q9ERD9
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Top anti-Indoleamine 2,3-Dioxygenase 1 Antibodies at antibodies-online.com

Showing 10 out of 177 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-INDO Antibody (C-term) (ABIN389194) in 293 cell line lysates (35 µg/lane). INDO(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with INDO antibody (C-term) (ABIN389194), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse Un-conjugated FACS, IHC, ELISA, WB Immunofluorescence Microscopy of Mouse anti-IDO1 Antibody. Cells: HEK293 cells. Fixation: 0.5% PFA. Expressing: mouse IDO-1 (left) and mouse IDO-2 (right). Primary antibody: IDO1 (2E2) monoclonal antibody. Antigen retrieval: not required. Secondary antibody: mouse secondary antibody at 1:10,000 for 45 min at RT. Localization: IDO-1 is located in the cytosol. Staining: IDO1 as red fluorescent signal with bis-benzimide nuclear counterstain (blue). 25 μL Log in to see 2 to 3 Days
$135.00
Details
Mouse Mouse Un-conjugated FACS, IP, IHC, ELISA, WB Western Blot of Mouse Anti-IDO1 Antibody. Lane 1: untreated HeLa cells. Lane 2: IFN-r treated HeLa cells. Load: 35 µg per lane. Primary antibody: IDO 1 Antibody at 1:1000 for overnight at 4°C. Secondary antibody: IRDye800™ mouse secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 41-42 kDa, 41-42 kDa for IDO-1. Other band(s): none. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Human Mouse PE FACS Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. 100 Tests Log in to see 8 to 9 Days
$320.25
Details
Human Mouse Alexa Fluor 488 FACS Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. 100 Tests Log in to see 8 to 9 Days
$341.25
Details
Human Mouse Allophycocyanin FACS Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human PBMC-derived myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. 100 Tests Log in to see 8 to 9 Days
$357.00
Details
Human Mouse Un-conjugated FACS, ICC Indoleamine 2,3-dioxygenase/IDO in A431 Human Cell Line. Indoleamine 2,3-dioxygenase/IDO was detected in immersion fixed A431 human epithelial carcinoma cells stimulated with 0.5 ng/mL of Recombinant Human IFN-gamma. Specific staining was localized to cytoplasm. Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human PBMC-derived myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 8 to 9 Days
$266.70
Details
Mouse Rabbit Un-conjugated IHC (fro), IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Sheep Un-conjugated EIA, FACS, IF, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$473.55
Details

IDO1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Indoleamine 2,3-Dioxygenase 1 Antibodies

  1. Human Monoclonal IDO1 Primary Antibody for FACS - ABIN4896116 : Kaltenmeier, Gawanbacht, Beyer, Lindner, Trzaska, van der Merwe, Härter, Grüner, Fabricius, Lotfi, Schwarz, Schütz, Hönig, Schulz, Kern, Bommer, Schrezenmeier, Kirchhoff, Jahrsdörfer: CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 references for ABIN4896116

  2. Human Polyclonal IDO1 Primary Antibody for EIA, IHC (p) - ABIN357869 : Maghzal, Thomas, Hunt, Stocker: Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN357869

  3. Human Polyclonal IDO1 Primary Antibody for EIA, FACS - ABIN1107630 : Grohmann, Fallarino, Puccetti: Tolerance, DCs and tryptophan: much ado about IDO. in Trends in immunology 2003 (PubMed)
    Show all 2 references for ABIN1107630

  4. Human Polyclonal IDO1 Primary Antibody for IHC (p), WB - ABIN389194 : Scheler, Wenzel, Tüting, Takikawa, Bieber, von Bubnoff: Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation? in The American journal of pathology 2007 (PubMed)
    Show all 2 references for ABIN389194

  5. Human Monoclonal IDO1 Primary Antibody for FACS, ICC - ABIN4899442 : Bonanno, Mariotti, Procoli, Folgiero, Natale, De Rosa, Majolino, Novarese, Rocci, Gambella, Ciciarello, Scambia, Palumbo, Locatelli, De Cristofaro, Rutella: Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma. in Journal of translational medicine 2013 (PubMed)

  6. Mouse (Murine) Polyclonal IDO1 Primary Antibody for IHC (fro), IHC (p) - ABIN1107631 : Hill, Pereira, Chauveau, Zagani, Remy, Tesson, Mazal, Ubillos, Brion, Asghar, Ashgar, Mashreghi, Kotsch, Moffett, Doebis, Seifert, Boczkowski, Osinaga, Anegon: Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)

  7. Human Monoclonal IDO1 Primary Antibody for FACS - ABIN4896118 : Lood, Tydén, Gullstrand, Klint, Wenglén, Nielsen, Heegaard, Jönsen, Kahn, Bengtsson: Type I interferon-mediated skewing of the serotonin synthesis is associated with severe disease in systemic lupus erythematosus. in PLoS ONE 2015 (PubMed)

  8. Mouse (Murine) Monoclonal IDO1 Primary Antibody for FACS, IHC - ABIN1043820 : Mellor, Munn: IDO expression by dendritic cells: tolerance and tryptophan catabolism. in Nature reviews. Immunology 2004 (PubMed)

  9. Human Monoclonal IDO1 Primary Antibody for FACS - ABIN4896114 : Chimal-Ramírez, Espinoza-Sánchez, Chávez-Sánchez, Arriaga-Pizano, Fuentes-Pananá: Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes. in Journal of immunology research 2016 (PubMed)

More Antibodies against Indoleamine 2,3-Dioxygenase 1 Interaction Partners

Cow (Bovine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Differential expression of CD25 (show IL2RA Antibodies) and IDO mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

  2. IDO may be involved in downregulating immune responses to M. avium subsp. paratuberculosis and other virulent mycobacteria, which may be an example of the pathogen harnessing host immunoregulatory pathways to aid survival.

  3. INDO participates in IFN-gama-induced death of bovine luteal cells, through a mechanism that involves degradation of tryptophan, thereby reducing tryptophan concentrations to a point insufficient to meet luteal cells needs

Rhesus Monkey Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. SIV-infected macaques exhibiting progression to AIDS displayed greater expression of TGF-beta (show TGFB1 Antibodies) and indoleamine 2,3 dioxygenase in CD8 (show CD8A Antibodies)+ T cells from mesentric lymph nodes.

Human Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Our results identified FGL2 (show FGL2 Antibodies), GAL (show GAL Antibodies), SEMA4D (show SEMA4D Antibodies), SEMA7A (show SEMA7A Antibodies), and IDO1 as new candidate genes that could be involved in MSCs-mediated immunomodulation. FGL2 (show FGL2 Antibodies), GAL (show GAL Antibodies), SEMA4D (show SEMA4D Antibodies), SEMA7A (show SEMA7A Antibodies), and IDO1 genes appeared to be differentially transcribed in the different MSC (show MSC Antibodies) populations. Moreover, these genes were not similarly modulated following MSCs-exposure to inflammatory signals

  2. IDO mediated conversion of FOXP3 (show FOXP3 Antibodies) -T cells to Tregs predominantly occurs in children with inflammatory bowel disease.

  3. The study confirmed that high IDO expression in pancreatic adenocarcinoma was related to poor prognosis of patients. These findings provided evidence that IDO was involved in pancreatic adenocarcinoma progression and might serve as a relevant therapeutic target.

  4. ver-expression of CTLA4 (show CTLA4 Antibodies) and IDO1 was significantly associated with biochemical recurrence. Our results provide clues on the mechanisms of tumor development and point to potential biomarkers for early detection and treatment for prostate cancer in young men.

  5. IDO1 mRNA expression in cervical cancer

  6. IDO gene expression is a feature of aggressive non-muscle-invasive urothelial cell bladder carcinoma, suggesting a potential immunosuppressive role of IDO

  7. Data show that in the absence of indoleamine 2,3-dioxygenase (IDO) inhibition, fatty acid oxidation increased along with increased activity of carnitine palmitoyltransferase I (CPT1 (show CPT1A Antibodies)).

  8. High IDO1 expression is associated with cervical cancer.

  9. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-gamma (show IFNG Antibodies).

  10. These results indicate that the level of IDO expression may be associated with pregnancy-related complications, such as URSA, by affecting trophoblast cell proliferation and migration via the STAT3 (show STAT3 Antibodies) signaling pathway.

Mouse (Murine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Indoleamine-2,3-dioxygenase (IDO) production by Plasmacytoid dendritic cells (pDCs)is necessary to confer suppressive function to T-Cells, Regulatory (Tregs) in experimental autoimmune encephalomyelitis (EAE).

  2. our findings support the hypothesis elevated IDO activity in non-CNS due to virus infections causes pain hypersensitivity

  3. this study shows that IDO overexpression in dendritic cells attenuates acute allograft rejection

  4. This insight into IDO1's involvement in pro-tumorigenic inflammatory neovascularization may have important ramifications for IDO1 inhibitor development, not only in cancer where clinical trials are currently ongoing, but in other disease indications associated with neovascularization as well.

  5. Inhibition of IDO activity ameliorated Japanese encephalitis via enhancement of antiviral IFN-I/II innate and adaptive T-cell responses and increased central nervous system infiltration of peripheral leukocytes.

  6. Results suggest that IDO expression is implicated in immunosuppression and tumor progression in glioma cells; combining IDO inhibition with standard TMZ treatment could be an encouraging therapeutic strategy for patients with malignant glioma

  7. Data show that the expression of indoleamine 2, 3-dioxygenase 1 (IDO) was decreased after tumor cells were infected with Salmonella.

  8. Severity of sodium dodecyl sulfate-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88 (show MYD88 Antibodies)-NF-kB transcriptional networks.

  9. IDO1 deficiency does not affect inflammation in Systemic Juvenile Idiopathic Arthritis, Secondary Hemophagocytic Lymphohistiocytosis and a T cell-triggered cytokine release model.

  10. Data indicate that indolamine-2,3-dioxygenase (IDO) and Fibroblast activation protein alpha (show FAP Antibodies) (FAPalpha) were detectable in B16 melanoma tumor-bearing mice.

Pig (Porcine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

Indoleamine 2,3-Dioxygenase 1 (IDO1) Antigen Profile

Protein Summary

This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

Gene names and symbols associated with IDO1

  • indoleamine 2,3-dioxygenase 1 (IDO1) antibody
  • indoleamine 2,3-dioxygenase 1 (ido1) antibody
  • indoleamine 2,3-dioxygenase 1 (Ido1) antibody
  • indoleamine 2,3-dioxygenase 1-like (LOC100050681) antibody
  • cd107b antibody
  • Ido antibody
  • IDO-1 antibody
  • IDO1 antibody
  • Indo antibody

Protein level used designations for IDO1

indoleamine-pyrrole 2,3 dioxygenase , indoleamine 2,3-dioxygenase 2 , proto-IDO , putative indoleamine 2,3-dioxygenase , indoleamine 2,3-dioxygenase 1 , indolamine 2,3 dioxygenase , indole 2,3-dioxygenase , indoleamine-pyrrole 2,3-dioxygenase , IDO-1 , indoleamine 23-dioxygenase

GENE ID SPECIES
506281 Bos taurus
100037099 Xenopus laevis
100086385 Ornithorhynchus anatinus
448488 Xenopus (Silurana) tropicalis
464134 Pan troglodytes
571967 Danio rerio
574370 Macaca mulatta
100032999 Monodelphis domestica
100196903 Ovis aries
3620 Homo sapiens
15930 Mus musculus
66029 Rattus norvegicus
475574 Canis lupus familiaris
100519877 Sus scrofa
100050681 Equus caballus
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