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anti-Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) Antibodies

The protein encoded by ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. Additionally we are shipping ID1 Proteins (7) and ID1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ID1 15901  
ID1 25261 P41135
ID1 3397 P41134
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Top anti-ID1 Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of ID1 Antibody (Center)(ABIN655663) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ID1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:7812500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of U251 cells using ID1 / BHLHB24 Antibody (Center) Cat.-No AP52144PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of ID1 / BHLHB24 Antibody (Center) Cat.-No AP52144PU-N with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to ID1 on HeLa cell (antibody concentration 10 µg/mL). ID1 monoclonal antibody (M04), clone 4G11 Western Blot analysis of ID1 expression in Y-79. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB Western blot analysis of recombinant human Id1. Purified mouse anti-Id1 antibody (clone B30-1) used at 2 µg/mL recognizes a ~ 45 kDa band on 100 ng of recombinant human Id1-GST protein. Id1 has a calculated molecular weight of ~ 17 kD and GST at ~28 kDa. 0.1 mg Log in to see 5 to 6 Days
$270.92
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ID1 is approximately 0.1ng/ml as a capture antibody. Western Blot detection against Immunogen (42.79 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to ID1 on HeLa cell. [antibody concentration 10 ug/ml] ID1 monoclonal antibody (M04), clone 4G11 Western Blot analysis of ID1 expression in Y-79 . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of ID1 expression in HeLa (A), HepG2 (B), mouse liver (C), rat liver (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-ID1 Polyclonal Antibody, Unconjugated (ABIN700330) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse lymphoma tissue labeled with Anti-ID1 Polyclonal Antibody, Unconjugated (ABIN700330) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated DB, ICC Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-ID1 antibody. 50 μg Log in to see 7 to 9 Days
$285.71
Details

ID1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ID1 Antibodies

  1. Human Monoclonal ID1 Primary Antibody for WB - ABIN967545 : Cooper, Brady, Bilia, Iscove, Quesenberry: Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system. in Blood 1997 (PubMed)
    Show all 8 references for ABIN967545

  2. Human Monoclonal ID1 Primary Antibody for IF, WB - ABIN394362 : Yang, Li, Al-Lamki, Southwood, Zhao, Lever, Grimminger, Schermuly, Morrell: Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo. in Circulation research 2010 (PubMed)
    Show all 5 references for ABIN394362

  3. Human Polyclonal ID1 Primary Antibody for FACS, IF - ABIN655663 : Qian, Lee, Park, Kim, Kong: Id1 enhances RING1b E3 ubiquitin ligase activity through the Mel-18/Bmi-1 polycomb group complex. in Oncogene 2010 (PubMed)
    Show all 2 references for ABIN655663

  4. Human Polyclonal ID1 Primary Antibody for EIA, FACS - ABIN952815 : Hamajima, Komori, Preciado, Choo, Moribe, Murakami, Ondrey, Lin: The role of inhibitor of DNA-binding (Id1) in hyperproliferation of keratinocytes: the pathological basis for middle ear cholesteatoma from chronic otitis media. in Cell proliferation 2010 (PubMed)
    Show all 2 references for ABIN952815

  5. Human Monoclonal ID1 Primary Antibody for IF, ELISA - ABIN561410 : Phi, Choi, Lim, Lee, Wang, Park, Kim: ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma. in BMC cancer 2013 (PubMed)

  6. Human Monoclonal ID1 Primary Antibody for ELISA, WB - ABIN561409 : Chen, Forootan, Gosney, Forootan, Ke: Increased expression of Id1 and Id3 promotes tumorigenicity by enhancing angiogenesis and suppressing apoptosis in small cell lung cancer. in Genes & cancer 2014 (PubMed)

  7. Human Polyclonal ID1 Primary Antibody for WB - ABIN2792663 : Yang, Davies, Southwood, Long, Yang, Sobolewski, Upton, Trembath, Morrell: Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension. in Circulation research 2008 (PubMed)

More Antibodies against ID1 Interaction Partners

Zebrafish Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) interaction partners

  1. Gain and loss of id1 function in vivo demonstrated that Id1 promotes stem cell quiescence. The increased id1 expression observed in neural stem cells in response to injury appeared independent of inflammatory signals.

Mouse (Murine) Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) interaction partners

  1. demonstrated that Id1 and E2-2 (show TCF4 Antibodies) are critical regulators of EPCs function in vitro. Id1 interacts with E2-2 (show TCF4 Antibodies) and relieves the E2-2 (show TCF4 Antibodies)-mediated repression of FGFR1 (show FGFR1 Antibodies) and VEGFR2 (show KDR Antibodies) expression to modulate EPCs functions

  2. Endothelial ID1 up-regulation in inflamed colonic mucosa is an adaptive response that modulates the severity of tissue injury.

  3. these findings provide in vivo genetic evidence of Id1 functions as an oncogene (show RAB1A Antibodies) in breast cancer

  4. overexpression leads to systemic immunosuppression by downregulation of key molecules involved in dendritic cell differentiation and suppression of CD8 T-cell proliferation, thus promoting primary tumour growth and metastatic progression

  5. ID1/3 are crucial regulators of the adaptive antioxidant-mitochondrial response that promotes beta cell survival during oxidative stress through a novel link to the NFE2L2 (show NFE2L2 Antibodies)-small MAF (show MAF Antibodies) pathway.

  6. Using genetically modified mice, we found that loss of Id1 inhibited t(8;21) leukemia initiation and progression in vivo by abrogating protein kinase B (AKT)1 (show AKT1 Antibodies) activation, and that Id1 interacted with AKT1 (show AKT1 Antibodies) through its C terminus.

  7. We conclude that Id1 is potently angiogenic and can be up-regulated in endothelial progenitor cells

  8. Direct interaction between Id1 and Zrf1 (show DNAJC2 Antibodies) blocks Zrf1 (show DNAJC2 Antibodies) recruitment to chromatin thus impairing neural commitment of embryonic stem cells.During embryonic stem cell differentiation, Id1 levels decrease allowing Zrf1 (show DNAJC2 Antibodies) to activate neural genes.

  9. Data indicate that inhibitor of differentiation protein 1 ID1+ cells are self-renewing, multipotent stem/progenitor cells responsible for the long-term renewal of the intestinal epithelium.

  10. Studies demostrated the regulatory role of ID1 in the proliferation and metastasis of colorectal cancer.

Human Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) interaction partners

  1. Peritoneal VEGF-A (show VEGFA Antibodies) expression is regulated by TGF-beta1 (show TGFB1 Antibodies) through an ID1 pathway in women with endometriosis

  2. Id-1, a protein repressed by miR (show MLXIP Antibodies)-29b, facilitates TGFbeta1 (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies) in human ovarian cancer cells and represents a promising therapeutic target for treating ovarian cancer.

  3. Simultaneous high expression of ID1 and c-Jun or c-Fos was correlated with poor survival in esophageal squamous cell carcinoma patients.

  4. Id1 as an important modulator of molecular events during DPSC commitment and differentiation, which should be considered in dental research on tissue engineering.

  5. Therefore, we identified a tumorigenic role of Id-1 in OS and suggested a potential therapeutic target for OS patients.

  6. these findings provide in vivo genetic evidence of Id1 functions as an oncogene (show RAB1A Antibodies) in breast cancer

  7. ID1 overexpression may be associated with higher risk karyotype classification and act as an independent risk factor in young non-M3 acute myeloid leukemia (show BCL11A Antibodies) patients.

  8. Advanced melanoma patients, relative to healthy controls, express much higher levels of ID1 in myeloid peripheral blood cells.

  9. LIF (show LIF Antibodies) has a role in negatively regulating tumour-suppressor p53 (show TP53 Antibodies) through Stat3 (show STAT3 Antibodies)/ID1/MDM2 (show MDM2 Antibodies) in colorectal cancers

  10. Overexpression of ID1 is associated with colorectal neoplasia.

ID1 Antigen Profile

Protein Summary

The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ID1

  • inhibitor of DNA binding 1 (id1) antibody
  • inhibitor of DNA binding 1, dominant negative helix-loop-helix protein (ID1) antibody
  • inhibitor of DNA binding 1 (Id1) antibody
  • AI323524 antibody
  • bHLHb24 antibody
  • cb108 antibody
  • D2Wsu140e antibody
  • ID antibody
  • ID1 antibody
  • id6 antibody
  • ID125A antibody
  • Idb1 antibody
  • wu:fb57e11 antibody

Protein level used designations for ID1

inhibitor of DNA binding 1 , DNA-binding protein inhibitor id-1 , inhibitor of DNA binding 1, dominant negative helix-loop-helix protein , DNA-binding protein inhibitor ID-1 , inhibitor of DNA binding 6 , Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation) , Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation) , class B basic helix-loop-helix protein 24 , dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein) , inhibitor of differentiation 1 , helix-loop-helix protein

GENE ID SPECIES
100528658 Ictalurus punctatus
469912 Pan troglodytes
30493 Danio rerio
15901 Mus musculus
25261 Rattus norvegicus
3397 Homo sapiens
609779 Canis lupus familiaris
100522839 Sus scrofa
497011 Bos taurus
395282 Gallus gallus
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