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anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) Antibodies

IMPA1 encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second . Additionally we are shipping Inositol(myo)-1(or 4)-Monophosphatase 1 Proteins (18) and Inositol(myo)-1(or 4)-Monophosphatase 1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IMPA1 55980  
IMPA1 83523 P97697
IMPA1 3612 P29218
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Top anti-Inositol(myo)-1(or 4)-Monophosphatase 1 Antibodies at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-IMPA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (56.58 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB IMPA1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated WB Western Blot analysis of IMPA1 expression in transfected 293T cell line by IMPA1 MaxPab polyclonal antibody.Lane 1: IMPA1 transfected lysate(30.47 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (56.21 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IF, WB Western Blot analysis of IMPA1 expression in transfected 293T cell line by IMPA1 MaxPab polyclonal antibody.Lane 1: IMPA1 transfected lysate(30.20 KDa).Lane 2: Non-transfected lysate. IMPA1 MaxPab rabbit polyclonal antibody. Western Blot analysis of IMPA1 expression in Raw 264.7. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB   200 μL Log in to see 9 Days
$487.50
Details

IMPA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Rat (Rattus)


Human ,
,
,

Top referenced anti-Inositol(myo)-1(or 4)-Monophosphatase 1 Antibodies

  1. Human Polyclonal IMPA1 Primary Antibody for ELISA, WB - ABIN561484 : Andreassi, Zimmermann, Mitter, Fusco, De Vita, Devita, Saiardi, Riccio: An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons. in Nature neuroscience 2010 (PubMed)
    Show all 2 references for ABIN561484

  2. Cow (Bovine) Polyclonal IMPA1 Primary Antibody for WB - ABIN2787799 : Ohnishi, Ohba, Seo, Im, Sato, Iwayama, Furuichi, Chung, Yoshikawa: Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Inositol(myo)-1(or 4)-Monophosphatase 1 Interaction Partners

Mouse (Murine) Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) interaction partners

  1. IMPase has a role in intracellular myo (show SYNPO2 Antibodies)-inositol synthesis in craniofacial development and the maintenance of proper brain function

  2. local synthesis of IMPA1 is required for neurotrophin (show BDNF Antibodies)-dependent axon growth; selective regulation of IMPA1 levels in axons may provide a target for the development of new therapeutic strategies for specific neurological and psychiatric diseases

  3. IMPA1 was expressed in round spermatids

  4. Results suggest that calbindin D28k (show CALB1 Antibodies) acts as an activity-dependent sensor that targets membrane/cytoskeleton-bound myo (show SYNPO2 Antibodies)-inositol monophosphatase in central neurons.

  5. IMPA2 (show IMPA2 Antibodies) has a separate function in vivo from that of IMPA1

  6. IMPA1-/- mouse represents a novel model to study inositol homeostasis, and indicates that genetic inactivation of IMPA1 can mimic some actions of lithium

Human Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) interaction partners

  1. The current study did not support a substantial role of the upregulation of IMPase in bipolar disorder, although the lithium-insensitivity trait seen in IMPA2 (show IMPA2 Antibodies) transgenic mice might represent some aspect relevant to the inositol depletion hypothesis.

  2. IMPA2 (show IMPA2 Antibodies) has a separate function in vivo from that of IMPA1

Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) Antigen Profile

Protein Summary

This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.

Gene names and symbols associated with IMPA1

  • inositol(myo)-1(or 4)-monophosphatase 1 (impa1) antibody
  • inositol (myo)-1(or 4)-monophosphatase 1 (Impa1) antibody
  • Inositol (myo)-1(or 4)-monophosphatase 1 (Impa1) antibody
  • inositol monophosphatase (impa1) antibody
  • inositol(myo)-1(or 4)-monophosphatase 1 (IMPA1) antibody
  • 2610002K09Rik antibody
  • 2900059K10Rik antibody
  • AI325909 antibody
  • IMP antibody
  • impa antibody
  • zgc:100926 antibody

Protein level used designations for IMPA1

inositol monophosphatase 1 , Inositol monophosphatase , IMP 1 , IMPase 1 , inositol-1(or 4)-monophosphatase 1 , lithium-sensitive myo-inositol monophosphatase A1 , myo-inositol monophosphatase

GENE ID SPECIES
437018 Danio rerio
100301752 Oncorhynchus mykiss
100380569 Salmo salar
55980 Mus musculus
83523 Rattus norvegicus
397905 Xenopus laevis
3612 Homo sapiens
444552 Xenopus laevis
477925 Canis lupus familiaris
397425 Sus scrofa
281865 Bos taurus
100174641 Pongo abelii
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