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anti-Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) Antibodies

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. Additionally we are shipping INPP4B Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
INPP4B 234515 Q6P1Y8
INPP4B 116699 Q9QWG5
INPP4B 8821 O15327
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Top anti-INPP4B Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of INPP4B Antibody (Center) (ABIN652849) in MCF-7 cell line lysates (35 µg/lane). INPP4B (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with INPP4B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged INPP4B is 1 ng/ml as a capture antibody. Western Blot detection against Immunogen (31.57 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

INPP4B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Rat (Rattus) ,


Human , ,
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Top referenced anti-INPP4B Antibodies

  1. Human Polyclonal INPP4B Primary Antibody for FACS, IHC (p) - ABIN652849 : Norris, Atkins, Majerus: The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family. in The Journal of biological chemistry 1997 (PubMed)

More Antibodies against INPP4B Interaction Partners

Mouse (Murine) Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) interaction partners

  1. Study provides evidence that INPP4B loss can promote follicular-like thyroid cancer progression and metastasis in the context of PTEN (show PTEN Antibodies) haploinsufficiency through the isoform-specific regulation of AKT (show AKT1 Antibodies) signaling at the endosomes.

  2. Results provide evidence that INPP4B is a bona fide tumor suppresso (show PTEN Antibodies)r whose function is particularly important in situations of PTEN deficiency. Biochemical data demonstrates that INPP4B directly dephosphorylates PtdIns(3,4 (show PTEN Antibodies),5)P3.

  3. ERalpha (show ESR1 Antibodies) plays a protective role in bladder cancer initiation and growth at least partly via modulating the INPP4B/Akt (show AKT1 Antibodies) pathway.

  4. mice carrying the longer-latency Inpp4b allele(474R/548P)) exhibited significantly longer cortical motor evoked potential latencies indicating that INPP4B regulates nerve conduction velocity

  5. Hyperactivation of the PI3K/AKT (show AKT1 Antibodies) pathway caused by the decrease in INPP4B in granulosa cells promotes an ovarian environment defective in folliculogenesis and conducive to teratoma (show DND1 Antibodies) formation.

  6. In vivo mice deficient in Inpp4b displayed increased osteoclast differentiation rate and potential resulting in decreased bone mass and osteoporosis

  7. This study provides first insight for a physiological role of PI-4-phosphatase II in the proerythroblast by controlling Epo (show EPO Antibodies) responsiveness through a negative regulation of the PI3K/Akt (show AKT1 Antibodies) pathway

Human Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) interaction partners

  1. The incidence of INPP4B loss of heterozygosity was significantly higher in the triple-negative breast tumor subtype and positively correlated with PTEN (show PTEN Antibodies) loss of heterozygosity.

  2. Data show that activation of serum- and glucocorticoid-regulated kinase 3 (SGK3 (show SGK3 Antibodies)) plays an important role in inositol polyphosphate 4-phosphatase type II (INPP4B)-mediated melanoma cell proliferation.

  3. Study provides evidence that INPP4B loss can promote follicular-like thyroid cancer progression and metastasis in the context of PTEN (show PTEN Antibodies) haploinsufficiency through the isoform-specific regulation of AKT (show AKT1 Antibodies) signaling at the endosomes.

  4. Studies in human tissues suggest that reductions in INPP4B and PTEN (show PTEN Antibodies) co-occur in human thyroid and endometrial cancers. INPP4B may therefore be an important regulator of cancer progression, especially in the context of PTEN (show PTEN Antibodies) insufficiency.

  5. Given that INPP4B loss has been found in 40% of ovarian cancer patients, this study provides the rationale for establishing INPP4B as a biomarker of PARP (show COL11A2 Antibodies) inhibitor response.

  6. Epigenetic inactivation of INPP4B is one of the key mechanisms in activating PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling cascade and playing a role in the tumorigenesis of nasopharyngeal carcinoma.

  7. There were no significant associations of PIK3CA (show PIK3CA Antibodies) copy number, pAKt (show AKT1 Antibodies), or INPP4B with trastuzumab efficacy.

  8. INPP4B is a novel suppressor of oncogenic PKC (show PRRT2 Antibodies) signaling, further emphasizing the role of INPP4B in maintaining normal physiology of the prostate epithelium and suppressing metastatic potential of prostate tumors.

  9. INPP4B overexpression is associated with therapy resistance in acute myeloid leukemia (show BCL11A Antibodies)

  10. ). We find that RAD50 (show RAD50 Antibodies) and INPP4B expression levels have a synergistic influence on breast cancer survival, possibly through their effects on treatment response.

INPP4B Antigen Profile

Protein Summary

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme.

Gene names and symbols associated with INPP4B

  • inositol polyphosphate-4-phosphatase, type II (Inpp4b) antibody
  • inositol polyphosphate-4-phosphatase, type II, 105kDa (INPP4B) antibody
  • E130107I17Rik antibody

Protein level used designations for INPP4B

inositol polyphosphate 4-phosphatase type II beta isoform , type II inositol 3,4-bisphosphate 4-phosphatase , type II inositol-3,4-bisphosphate 4-phosphatase , inositol polyphosphate 4-phosphatase type II , inositol polyphosphate-4-phosphatase type II 105kD , inositol polyphosphate-4-phosphatase, type II, 105kD , inositol polyphosphate 4-phosphatase II; 4-phosphatase II

GENE ID SPECIES
234515 Mus musculus
116699 Rattus norvegicus
8821 Homo sapiens
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