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anti-Integrin alpha 4 (ITGA4) Antibodies

The product of ITGA4 belongs to the integrin alpha chain family of proteins. Additionally we are shipping Integrin alpha 4 Kits (5) and Integrin alpha 4 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITGA4 16401 Q00651
ITGA4 311144  
ITGA4 3676 P13612
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Top anti-Integrin alpha 4 Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit Anti Integrin alpha 4/CD49d/Integrin ?4 Polyclonal Antibody, Unconjugated (ABIN671301) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse splenocytes probed with Rabbit Anti-Integrin alpha 4/CD49d Polyclonal Antibody, PE-Cy5 Conjugated . 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human laryngeal carcinoma labeled with Anti-Integrin alpha 4+Beta 7 Polyclonal Antibody, Unconjugated (ABIN677063) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse lung labeled with Anti-Integrin alpha 4+Beta 7 Polyclonal Antibody, Unconjugated (ABIN677063) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, treated with PMA 125ng/ml 30', using Integrin alpha4 (Ab-1027) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Bat Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Mouse Un-conjugated FACS, IFA   0.2 mg Log in to see 4 to 5 Days
$577.87
Details
Mouse Rat Un-conjugated Func, FACS Staining of C57Bl/6 splenocytes with 0.5 µg of Purified Rat IgG2a Iso Cntrl (ABIN287084) (open histogram) or 0.5 µg of Purified anti -mouse LPAM -1 (DATK32) (colored histogram) followed by Biotin Anti -Rat IgG (ABIN286915)and Streptavidin -PE (ABIN286891). Cells in the lymphocyte gate were used for analysis. 500 μg Log in to see 5 to 6 Days
$343.20
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details

ITGA4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Integrin alpha 4 Antibodies

  1. Human Polyclonal ITGA4 Primary Antibody for IF (p), IHC (p) - ABIN677063 : Tong, Dou, Wang, Yu, Wu, Lu, Chou, Wang, Kong, Dai, Xia: Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues. in Toxicology and applied pharmacology 2014 (PubMed)
    Show all 2 references for ABIN677063

  2. Human Polyclonal ITGA4 Primary Antibody for WB - ABIN871718 : Iida, Meijne, Oegema, Yednock, Kovach, Furcht, McCarthy: A role of chondroitin sulfate glycosaminoglycan binding site in alpha4beta1 integrin-mediated melanoma cell adhesion. in The Journal of biological chemistry 1998 (PubMed)
    Show all 2 references for ABIN871718

  3. Human Polyclonal ITGA4 Primary Antibody for IF (p), IHC (p) - ABIN671301 : Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells. in PLoS ONE 2014 (PubMed)

More Antibodies against Integrin alpha 4 Interaction Partners

Rhesus Monkey Integrin alpha 4 (ITGA4) interaction partners

  1. Administration of a novel recombinant antibody against alpha4beta7 gut (show GUSB Antibodies)-homing integrin during acute lentiviral infection prevents mobilization of cell lineages of the innate immune system and protects the gut (show GUSB Antibodies) tissues from acute lentiviral infection.

Mouse (Murine) Integrin alpha 4 (ITGA4) interaction partners

  1. These results suggest that Tie2 (show TEK Antibodies) signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (show VCAM1 Antibodies).

  2. ITGA4 expression enhances metastasis in MYCN (show MYCN Antibodies) low neuroblastoma (show ARHGEF16 Antibodies).

  3. CD49d-high-expressing Th1 (show HAND1 Antibodies) memory phenotype CD4 (show CD4 Antibodies)+ T cells with enhanced B cell helper activity develop early in the peritoneal cavity.

  4. Data suggest that bortezomib mobilizes hematopoietic stem cells (HSPCs) by modulation of the integrin alpha4beta1 (VLA)-4/vascular cell adhesion molecule-1 (VCAM-1 (show VCAM1 Antibodies)) axis.

  5. Consistent with a role of alpha4beta7 in the generation of intestinal mononuclear phagocytes, bone marrow cells from beta7(-/-) mice poorly reconstituted small intestine retinoic acid (RA)-producing CD11c (show ITGAX Antibodies)(hi) dendritic cells.

  6. SP/drug efflux functionality of hematopoietic progenitors is controlled by mesenchymal niche through VLA-4/CD44 (show CD44 Antibodies) axis.

  7. We conclude that integrin alpha4beta1 is necessary for CD4 (show CD4 Antibodies)(+) T cell-mediated protection against C. trachomatis infection in the genital mucosa.

  8. Mobilization of bone marrow-derived cells by G-CSF (show CSF3 Antibodies) boosted migration along the VCAM-1 (show VCAM1 Antibodies)/VLA-4 axis and reduced apoptosis of cardiomyocytes.

  9. PI3-kinase gamma (show PIK3CG Antibodies) promotes Rap1a (show RAP1A Antibodies)-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth.

  10. alpha(4) and alpha(9) integrins interacting with OPN (show SPP1 Antibodies) via the SLAYGLR domain play a key role in macrophage biology by regulating migration, survival, and accumulation.

Human Integrin alpha 4 (ITGA4) interaction partners

  1. Enhanced susceptibility of activated endocervical CD4 (show CD4 Antibodies)+ T cells to HIV may be related to increased CCR5 (show CCR5 Antibodies) expression by these cell subsets, but did not appear to be due to direct interaction of integrins a4b7 or a4b1 with HIV envelope.

  2. knockdown of PTTG1 (show PTTG1 Antibodies) increased expression of integrin alpha 4 (ITGA4), ITGA5 (show ITGA5 Antibodies), and integrin beta 1 (ITGB1 (show ITGB1 Antibodies)); otherwise, RhoA (show RHOA Antibodies) expression was significantly decreased

  3. Integrin alpha 2 (show ITGA2 Antibodies) and alpha 4 Yxxphi motifs interact with the endocytic clathrin adaptor, AP2 complex (show AP2B1 Antibodies).

  4. ITGA4 expression enhances metastasis in MYCN (show MYCN Antibodies) low neuroblastoma (show ARHGEF16 Antibodies).

  5. Data show that a small molecule inhibitor of the MYC (show MYC Antibodies) transcription factor can be an effective anticancer agent when delivered using a integrin alphavbeta3 (show ITGAV Antibodies) and VLA-4-targeted nanotherapy approach.

  6. Collectively, these data suggest a role for alpha4beta7 integrin in HIV infection that is influenced by both viral and host factors including the sequence of the HIV gp120 (show ITIH4 Antibodies) alpha4beta7 binding motif, the cytokine milieu and bacterial vaginosis in the genital tract.

  7. CD49d and CD26 (show DPP4 Antibodies) have independent prognostic value and we suggest its use as a part of routine panel for prognostic stratification of CLL.

  8. Hypermethylation of ITGA4 promoter is increased in inflamed colon tissue.

  9. Regulatory CD4 (show CD4 Antibodies) T cells (Treg) cells in co-infected patients present phenotypic alterations and might have dysfunction marked by low expression of Foxp3 (show FOXP3 Antibodies) and increased expression of molecules not frequently seen on Treg cells, such as CD49d.

  10. High VLA-4 expression was independently associated with a high probability of complete remission in acute myeloid leukemia (show BCL11A Antibodies) patients.

Integrin alpha 4 (ITGA4) Antigen Profile

Protein Summary

The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.

Gene names and symbols associated with ITGA4

  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4) antibody
  • integrin alpha 4 (Itga4) antibody
  • integrin, alpha 4 (Itga4) antibody
  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (itga4) antibody
  • CD49D antibody
  • IA4 antibody

Protein level used designations for ITGA4

integrin alpha 4 , CD49 antigen-like family member D , LPAM subunit alpha , VLA-4 receptor, alpha 4 subunit , VLA-4 subunit alpha , integrin alpha-4 , integrin alpha-IV , lymphocyte Peyer patch adhesion molecules subunit alpha , 269C wild type , antigen CD49D, alpha-4 subunit of VLA-4 receptor , integrin alpha-4 subunit , very late activation protein 4 receptor, alpha 4 subunit

GENE ID SPECIES
470596 Pan troglodytes
704745 Macaca mulatta
16401 Mus musculus
311144 Rattus norvegicus
3676 Homo sapiens
397839 Xenopus laevis
Selected quality suppliers for anti-Integrin alpha 4 (ITGA4) Antibodies
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