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IRF2BP2 encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Additionally we are shipping IRF2BP2 Kits (2) and and many more products for this protein.
Showing 10 out of 59 products:
Human Polyclonal IRF2BP2 Primary Antibody for EIA, FACS - ABIN952948
Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004
Show all 2 references for ABIN952948
Human Polyclonal IRF2BP2 Primary Antibody for EIA, IHC (p) - ABIN1450159
Childs, Goodbourn: Identification of novel co-repressor molecules for Interferon Regulatory Factor-2. in Nucleic acids research 2003
ETO2 (show CBFA2T3 Antibodies) and IRF2BP2 interacting with the NCOR1 (show NCOR1 Antibodies)/SMRT (show NCOR2 Antibodies) co-repressor complex, suppresses the expression of erythroid genes until erythroid differentiation.
A deletion variant that lowers IRF2BP2 expression predisposes to coronary artery disease in humans.
analysis of an IRF2BP2-CDX1 (show CDX1 Antibodies) fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma
Nuclear localization of IRF2BP2 depends on phosphorylation near a conserved NLS (show ALDH1A2 Antibodies). Changes in phosphorylation status likely control nucleocytoplasmic localization of IRF2BP2 during muscle differentiation.
results indicate that DIF-1 plays a key role in breast cancer cell survival
Data demonstrate that IRF-2BP2 is a negative regulator of the NFAT1 (show NFAT1 Antibodies) transcription factor and suggest that NFAT1 (show NFAT1 Antibodies) repression occurs at the transcriptional level.
IRF2BP2 works with TEAD transcription factors to upregul (show VEGFA Antibodies)ate the expression of VEGFA in skeletal and cardiac muscle. IRF2BP2 protein levels are increased in response to tissue ischemia.
Identification of IRF-2 binding protein 1 (show IRF2BP1 Antibodies) and IRF-2 binding protein 2 as co-repressor molecules for interferon regulatory factor-2 (show IRF2 Antibodies).
Ablation of IRF2BP2 in macrophages worsens atherosclerosis in mice.
IRF2BP2 is a novel ischemia-induced coactivator of VEGFA (show VEGFA Antibodies) expression that may contribute to revascularization of ischemic cardiac and skeletal muscles.
This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
IRF-2-binding protein 2
, interferon regulatory factor 2-binding protein 2
, putative nuclear protein of bilaterial origin (49.6 kD) (5N852)