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Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Additionally we are shipping Interleukin 1 Family Member 9 Antibodies (63) and Interleukin 1 Family Member 9 Kits (35) and many more products for this protein.
Showing 10 out of 35 products:
The data identify a novel role for IL-36 signaling in colonic inflammation and indicate that the IL-36R (show IL1RL2 Proteins) pathway may represent a novel target for therapeutic intervention.
IL-1 (show IL1A Proteins) and IL-36 have roles as inflammatory mediators in pustular psoriasis in a mouse model
An essential role of C/EBPbeta (show CEBPB Proteins) in the regulation of the Il36A (show IL1F6 Proteins) gene via the proximal half-CRE*C/EBP (show CEBPA Proteins) element in response to inflammatory stimuli.
IL-36alpha acts as a pro-inflammatory cytokine in the lungs independent of both IL-1alpha and IL-1beta (show IL1B Proteins).
Data presented herein shed further light on involvement of T-bet in innate immunity and suggest that IL-36gamma, besides IFNgamma, may contribute to functions of this transcription factor in immunopathology.
Interleukin-36 (show IL1F6 Proteins) (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
A critical role of IL-36R (show IL1RL2 Proteins) ligands in the interface between innate and adaptive immunity, leading to the stimulation of T helper responses.
Transcripts for IL-1F5, -1F6, -1F8, and -1F9 are all significantly increased in the involved skin of bitransgenic mice compared with their monotransgenic controls.
IL-1F6 (show IL1F6 Proteins) can be externalized via a stimulus-coupled mechanism comparable to that used by IL-1beta (show IL1B Proteins)
Autocrine and Paracrine Regulation of Keratinocyte Proliferation through a Novel Nrf2 (show GABPA Proteins)-IL-36gamma Pathway
IL-36gamma, a member of the IL-1 (show IL1A Proteins) superfamily, is involved in host defense and contributes to proinflammatory responses and development of inflammatory diseases.
Study shows that plasma concentrations of IL-36alpha and IL-36gamma are overexpressed in active systemic lupus erythematosus patients and that IL-36alpha has a substantial pro-inflammatory effect through regulation of IL-6 (show IL6 Proteins) and CXCL8 (show IL8 Proteins) production.
IRF6 (show IRF6 Proteins) is likely to promote inflammation to P. gingivalis through its regulation of IL-36gamma.
Findings indicate that Interleukin (IL)-1beta (show IL1B Proteins)-induced interleukin 36 gamma (IL-36gamma) expression is mediated by the activation of transcriptional factors, NF-kappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins) and AP-1 (c-jun (show JUN Proteins)).
IL36G was identified as strong regulators of skin pathology in both lesional and non-lesional skin samples.
Decreased Langerhans cell responses to IL36G: altered innate immunity in patients with recurrent respiratory papillomatosis
Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
Regulation and function of the IL-1 (show IL1A Proteins) family cytokine IL-1F9 in human bronchial epithelial cells.
Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
, IL-1 epsilon
, interleukin 1 family, member 6 (epsilon)
, interleukin 1 family, member 9
, interleukin-1 epsilon
, interleukin-1 family member 6
, interleukin-1 homolog 1
, interleukin-36 alpha
, interleukin-1 family member 9
, interleukin-36 gamma
, IL-1 related protein 2
, IL-1-related protein 2
, interleukin 1-related protein 2