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IL17RC encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Additionally we are shipping Interleukin 17 Receptor C Proteins (14) and Interleukin 17 Receptor C Kits (8) and many more products for this protein.
Showing 10 out of 69 products:
Human Polyclonal IL17RC Primary Antibody for EIA, WB - ABIN493073
Fossiez, Djossou, Chomarat, Flores-Romo, Ait-Yahia, Maat, Pin, Garrone, Garcia, Saeland, Blanchard, Gaillard, Das Mahapatra, Rouvier, Golstein, Banchereau, Lebecque: T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. in The Journal of experimental medicine 1996
Show all 3 references for ABIN493073
Human Polyclonal IL17RC Primary Antibody for EIA, WB - ABIN493071
Toy, Kugler, Wolfson, Vanden Bos, Gurgel, Derry, Tocker, Peschon: Cutting edge: interleukin 17 signals through a heteromeric receptor complex. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 3 references for ABIN493071
Human Polyclonal IL17RC Primary Antibody for WB - ABIN442449
Johnston, Guzman, Swindell, Wang, Kang, Gudjonsson: Early tissue responses in psoriasis to the antitumour necrosis factor-α biologic etanercept suggest reduced interleukin-17 receptor expression and signalling. in The British journal of dermatology 2014
Show all 2 references for ABIN442449
Human Polyclonal IL17RC Primary Antibody for ELISA, WB - ABIN1451946
Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: The DNA sequence, annotation and analysis of human chromosome 3. ... in Nature 2006
human IL-17RC is essential for mucocutaneous immunity to C. albicans but is otherwise largely redundant.
results suggested a potential involvement of IL-17RC+CD8 (show CD8A Antibodies)+ T cells in pathogenesis of ocular sarcoidosis
IL-17RC predisposes to the development of adolescent idiopathic scoliosis in a Chinese Han population.
Data show that IL-17RA (show IL17RA Antibodies), IL-17RC, IL-22R1, ERK1/2 (show MAPK1/3 Antibodies) MAPK (show MAPK1 Antibodies) and NF-kappaB (show NFKB1 Antibodies) pathways are involved in Th17 cytokine-induced proliferation.
Overall, our study found a significant association of IL-17RC gene polymorphisms with AIS (show AR Antibodies) in a Chinese Han population, indicating IL-17RC gene may be as a susceptibility gene for AIS (show AR Antibodies).
IL-17 (show IL17A Antibodies) and its receptor IL-17RC are involved in rheumatoid arthritis synovial fluid-mediated chemotaxis in human lung microvascular endothelial cell culture.
IL-17RL exists as multiple isoforms due to extensive alternative splicing. Changes in RNA IL-17RL splicing occur in advanced cancers.
The biologic activity of IL-17 (show IL17A Antibodies) is dependent on a complex composed of receptors IL-17RA (show IL17RA Antibodies) and IL-17RC.
IL-17RC functions as a receptor for both IL-17A (show IL17A Antibodies) and IL-17F (show IL17F Antibodies); a soluble version of this protein should be an effective antagonist of IL-17A (show IL17A Antibodies) and IL-17F (show IL17F Antibodies) mediated inflammatory diseases.
IL-17A (show IL17A Antibodies)-induced IL-6 (show IL6 Antibodies), IL-8 (show IL8 Antibodies), and CCL20 (show CCL20 Antibodies) secretion was dependent on both IL-17RA (show IL17RA Antibodies) and IL-17RC, which are overexpressed in RA patients.
Interleukin-17 receptor C deficient mice had higher rates of apoptosis in castration-resistant prostate cancer.
Data show that signaling in IL-17RC(-/-) fibroblasts required the SEF (show IL17RD Antibodies)/IL-17R signaling domain (SEFIR).
IL-17RC is essential for mediating the functions of IL-17A (show IL17A Antibodies), IL-17F (show IL17F Antibodies), and IL-17A (show IL17A Antibodies)/F both in vitro and in vivo and directly participates in the pathogenesis of central nervous system inflammation.
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
interleukin 17 receptor C
, interleukin-17 receptor C
, interleukin-17 receptor C-like
, IL-17 receptor C
, IL17F receptor
, interleukin-17 receptor homolog
, interleukin-17 receptor-like protein