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IL17RC Products

(Interleukin 17 Receptor C (IL17RC))

Categories

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011].

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Featured IL17RC Categories

IL17RC Antibodies

High quality antibodies with extensive validation data.

IL17RC ELISA Kits

Reliable ELISA kits for a wide range of species.

IL17RC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL17RC Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7443296
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7185043
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7438613
Quantity 100 μL
Datasheet Datasheet

Recommended IL17RC ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1889355
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1672882
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4883325
Quantity 96 tests
Datasheet Datasheet

Recommended IL17RC Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274895
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7013551
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307719
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our IL17RC products

Calcinotto, Brevi, Chesi, Ferrarese, Garcia Perez, Grioni, Kumar, Garbitt, Sharik, Henderson, Tonon, Tomura, Miwa, Esplugues, Flavell, Huber, Canducci, Rajkumar, Bergsagel, Bellone: "Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression." in: Nature communications, Vol. 9, Issue 1, pp. 4832, (2019) (PubMed).

Das, Raundhal, Chen, Oriss, Huff, Williams, Ray, Ray: "Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response." in: JCI insight, Vol. 2, Issue 17, (2017) (PubMed).

Li, Gao, Tang, Liu, Wu, Qu, Long, Li, Liu, Liu, Yuan, Mao, Liu, Zheng, Wang, Wang, Yang: "Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells." in: Frontiers in pharmacology, Vol. 8, pp. 959, (2017) (PubMed).

Liu, Lauridsen, Amezquita, Pierce, Jane-Wit, Fang, Pellowe, Kirkiles-Smith, Gonzalez, Pober: "IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 6, pp. 2400-8, (2016) (PubMed).

Halwani, Al-Kufaidy, Vazquez-Tello, Pureza, BaHammam, Al-Jahdali, Alnassar, Hamid, Al-Muhsen: "IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma." in: PLoS ONE, Vol. 9, Issue 12, pp. e114604, (2016) (PubMed).

Schminke, Trautmann, Mai, Miosge, Blaschke: "Interleukin 17 inhibits progenitor cells in rheumatoid arthritis cartilage." in: European journal of immunology, Vol. 46, Issue 2, pp. 440-5, (2016) (PubMed).

Yuan, Zhang, Zhuang, Zhang, Bai, Hou: "Interleukin-17 Stimulates STAT3-Mediated Endothelial Cell Activation for Neutrophil Recruitment." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 6, pp. 2340-56, (2015) (PubMed).

Johnston, Guzman, Swindell, Wang, Kang, Gudjonsson: "Early tissue responses in psoriasis to the antitumour necrosis factor-α biologic etanercept suggest reduced interleukin-17 receptor expression and signalling." in: The British journal of dermatology, Vol. 171, Issue 1, pp. 97-107, (2014) (PubMed).

Liu: "Overstimulation can create health problems due to increases in PI3K/Akt/GSK3 insensitivity and GSK3 activity." in: SpringerPlus, Vol. 3, pp. 356, (2014) (PubMed).

Wu, Jin, Wang, Liu, Shen, Chen, Hannes, Li, Hirani, Jawad, Sen, Chan, Nussenblatt, Wei: "Overexpression of IL-17RC associated with ocular sarcoidosis." in: Journal of translational medicine, Vol. 12, pp. 152, (2014) (PubMed).

Synonyms and alternative names related to IL17RC

interleukin 17 receptor C (Il17rc), interleukin 17 receptor C (IL17RC), 1110025H02Rik, Gm19850, IL-17RC, IL17-RC, IL17-RL, IL17RL, Il17rl

Protein level used designations for IL17RC

  • interleukin 17 receptor C
  • interleukin-17 receptor C
  • interleukin-17 receptor C-like
  • IL-17 receptor C
  • IL-17RL
  • IL17F receptor
  • IL17Rhom
  • interleukin-17 receptor homolog
  • interleukin-17 receptor-like protein
  • zcytoR14
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