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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (148) and IL27 Proteins (26) and many more products for this protein.
Showing 10 out of 48 products:
Mouse (Murine) IL27 Primary Antibody for ELISA - ABIN1672803
Larousserie, Charlot, Bardel, Froger, Kastelein, Devergne: Differential effects of IL-27 on human B cell subsets. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 3 references for ABIN1672803
Human IL27 Primary Antibody for ELISA - ABIN1672802
Larousserie, Bardel, Pflanz, Arnulf, Lome-Maldonado, Hermine, Brégeaud, Perennec, Brousse, Kastelein, Devergne: Analysis of interleukin-27 (EBI3/p28) expression in Epstein-Barr virus- and human T-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. in The American journal of pathology 2005
An association between the IL-27 single nucleotide polymorphism (SNP) rs153109 and Atrial Fibrillation was found in Chinese Han population. The G allele and GG genotype of rs153109 were associated with increased AF risk (odds ratio [OR]: 1.35, 95% confidence intervals [CI]=1.06-1.71, p=0.02 and OR: 1.66, 95% CI=1.03-2.65, p=0.03 in the recessive genetic model, respectively)
Study demonstrated that levels of circulating serum IL-27 were elevated in rheumatoid arthritis (RA) patients and were positively correlated with RA disease activity. Moreover, these concentrations decreased after effective immunosuppressant treatment suggesting its involvement in the pathogenesis of RA.
Data indicate that the genetic variant rs153109 in the 5' upstream region of interleukin 27 (IL-27) is significantly associated with ulcerative colitis (UC) in Chinese Han individuals.
this study shows that the serum levels of IL-27 are lower in Iranian diabetes type I patients compared to the healthy individuals
our findings showed a relationship between the IL-27 2905T/G genotype variant and the decreased susceptibility for developing cervical cancer. The IL-27 2905T/G genotype variant also modified the survival time in cervical cancer patients.
an IL-27/Stat3 (show STAT3 ELISA Kits) axis induces expression of programmed cell death 1 (show PDCD1 ELISA Kits) ligands (PD-L1 (show CD274 ELISA Kits)/2) on infiltrating macrophages in lymphoma
Interleukin-27 rs 153109 Single Nucleotide Polymorphism is associated with responses to therapy in Hepatitis C.
this study shows that IL-27 gene polymorphism is genetic risk factor for systemic lupus erythematosus in the Polish population, and that it predicts disease phenotype
Data indicate that the CC genotype of interleukin 27 (IL-27) single nucleotide polymorphism rs153109 was significantly more prevalent in pre-eclampsia (PE) cases than controls.
IL-27 is a viable candidate biomarker to identify bacterial infection among ED patients and is comparable with PCT (show UROD ELISA Kits).
recombinant IL-30 showed its biological activity by inhibiting Th17 differentiating from naive CD4 (show CD4 ELISA Kits)(+) T cells. Therefore, this method of express and purifying IL-30 provides novel procedures to facilitate structural and functions studies of IL-30.
An IL-27/Lag3 (show LAG3 ELISA Kits) axis enhances Foxp3 (show FOXP3 ELISA Kits)+ regulatory T cell-suppressive function and therapeutic efficacy.
IL-27 is one of the limited unique cytokines directly acting on hematopoietic stem cells (HSCs) to promote differentiation into myeloid progenitors during emergency myelopoiesis.
These results provide the first evidences that Fli-1 (show FLI1 ELISA Kits) positively regulates LPS (show TLR4 ELISA Kits)-induced IL-27 production in macrophages
of autocrine/paracrine mechanisms involving IL-27 in adipocytes under conditions of inflammatory stress that may link obesity with inflammatory diseases.
Increased IL-27 expression in bleomycin-induced pulmonary fibrosis was noted.
IL-27 induces the endothelial differentiation in cardiac resident stem cells through STAT3 (show STAT3 ELISA Kits)/Pim-1 (show PIM1 ELISA Kits) signaling pathway.
demonstrate that suppression mediated by interferon (show IFNA ELISA Kits) and IL-27 is a negative feedback mechanism for group 2 innate lymphoid cells function in vivo
Natural killer cells-dendritic cells interaction elicits a positive feedback loop for IFN-gamma (show IFNG ELISA Kits) and IL-27 production.
demonstrate the essential role of IL-27 signaling in regulating immune responses to extracellular protozoan infections
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
, IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interleukin 27 p28 subunit
, interluekin 27