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IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4\; MIM 147780). Additionally we are shipping Interleukin 33 Antibodies (368) and Interleukin 33 Kits (62) and many more products for this protein.
Showing 10 out of 107 products:
Mouse (Murine) Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2667522
Arend, Palmer, Gabay: IL-1, IL-18, and IL-33 families of cytokines. in Immunological reviews 2008
Show all 7 references for ABIN2667522
Human Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2666662
Mildner, Storka, Lichtenauer, Mlitz, Ghannadan, Hoetzenecker, Nickl, Dome, Tschachler, Ankersmit: Primary sources and immunological prerequisites for sST2 secretion in humans. in Cardiovascular research 2010
Show all 6 references for ABIN2666662
Human Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2002684
Cayrol, Girard: The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. in Proceedings of the National Academy of Sciences of the United States of America 2009
Show all 3 references for ABIN2002684
Human Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN1344110
Iikura, Suto, Kajiwara, Oboki, Ohno, Okayama, Saito, Galli, Nakae: IL-33 can promote survival, adhesion and cytokine production in human mast cells. in Laboratory investigation; a journal of technical methods and pathology 2007
Show all 3 references for ABIN1344110
Dog (Canine) Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2008834
Schmitz, Owyang, Oldham, Song, Murphy, McClanahan, Zurawski, Moshrefi, Qin, Li, Gorman, Bazan, Kastelein: IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. in Immunity 2005
Show all 2 references for ABIN2008834
In a CML (show BCR Proteins) patient with pruritus receiving imatinib mesylate, IL-31 (show IL31 Proteins) and IL-33 serum levels were significantly higher than controls. Imatinib could cause keratinocyte injury, the release of IL-33, and the consequent interaction with its receptor on mast cells, inducing IL-31 (show IL31 Proteins) secretion. The IL-31 (show IL31 Proteins)/IL-33 axis may be involved in the pathogenesis of skin side effects related to imatinib mesylate treatment.
IL-33 and ST2 are expressed in periapical granulomas and radicular cysts.
in breast tumors from 40 female patients with absent or present tumor necrosis there was significantly higher expression of IL-33, IL-33R and VEGF in breast cancer tissues with absent tumor necrosis. Both, IL-33 and IL-33R expression correlated with VEGF expression in tumor cells.
Data suggest that interleukin 33 (IL-33) may play an important role in the development of non-small cell lung cancer (NSCLC) and the targeted therapy.
rs7044343 polymorphism of IL-33 gene is associated with the susceptibility to systemic sclerosis in Turkish population.
In mild untreated asthma, the expression of IL-33 mRNA in bronchial mucosa is related to innate immune activation and allergic sensitization to HDM (show HDAC3 Proteins), rather than epithelial damage, and correlates with FeNO.
Serum IL-33 levels are suppressed in Sjogren syndrome patients.
Increased induction and expression of TSLP (show TSLP Proteins), IL-25 (show IL25 Proteins), and IL-33 from nasal epithelial cells contribute to the pathophysiology of eosinophilic chronic rhinosinusitis.
Serum IL-33 level is increased in children with ulcerative colitis as compared with control. Serum level correlated with the disease activity.
IL-33-ERK (show EPHB2 Proteins)/JNK (show MAPK8 Proteins)/p38 (show CRK Proteins)/Egr-1 (show EGR1 Proteins)/TSLP (show TSLP Proteins) axis involved in allergic skin Th2 inflammation
anti-allergic effect of anti-IL-33 antibodies associated with suppression of immunoglobulin free light chain and nitric oxide synthase in a murine model of allergic rhinitis
Data suggest that IL-33 and ST2 function as a developmental switch to license thermogenesis during the perinatal period.
some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of Graves' disease (GD) and Hashimoto's thyroiditis (HT) in Chinese Han population.
Furthermore, IL-33 injection modulates the innate immune response by polarizing microglia/macrophages toward an antiinflammatory phenotype and reducing the expression of proinflammatory genes, including IL-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins), and NLRP3 (show NLRP3 Proteins), in the cortices of APP (show APP Proteins)/PS1 (show PSEN1 Proteins) mice. Collectively, our results demonstrate a potential therapeutic role for IL-33 in AD.
absence of IL-33 has no negative consequences in normal bone homeostasis while high levels of circulating IL-33 contributes to pathological bone loss.
pre-treatment with the ERK1/2 inhibitor U0126 or anti-IL-33 antibody significantly abolished the ovalbumin (show OVA Proteins)-induced airway remodeling, increased expressions of IL-33
IL-33 promotes degranulation of bone marrow-derived mast cells and release of cytokines IL-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins) and TNF-alpha (show TNF Proteins).
pulmonary interstitial macrophages may not be a source of IL-33 during Respiratory syncytial virus infection
demonstrate a pathogenic role for IL-33-mediated eosinophilia and activation of Th2 immunity in chronic intestinal inflammation
IL-33 as a novel regulator of neutrophil function in antibacterial infection
IL-33 may be a key molecule operating in eosinophil-mediated fibrosis in high-dose-per fraction irradiated skin.
IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4\; MIM 147780). IL33 is a ligand for IL33R (IL1RL1\; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010
, DVS27-related protein
, interleukin-1 family member 11
, nuclear factor for high endothelial venules
, nuclear factor from high endothelial venules