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Interleukin 33 Proteins (IL33)

IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4\; MIM 147780). Additionally we are shipping Interleukin 33 Antibodies (368) and Interleukin 33 Kits (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL33 90865 O95760
IL33 77125 Q8BVZ5
IL33 361749 Q66H70
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Top Interleukin 33 Proteins at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 5 to 8 Days
$267.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 16 Days
$822.80
Details
HOST_Escherichia coli (E. coli) Dog Un-conjugated 100 μg Log in to see 16 Days
$822.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$211.97
Details
HOST_Escherichia coli (E. coli) Human His tag 0.05 mg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 4 to 6 Days
$850.67
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$190.24
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details

IL33 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine) , ,
,
Rat (Rattus)

Top referenced Interleukin 33 Proteins

  1. Mouse (Murine) Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2667522 : Arend, Palmer, Gabay: IL-1, IL-18, and IL-33 families of cytokines. in Immunological reviews 2008 (PubMed)
    Show all 7 references for ABIN2667522

  2. Human Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2666662 : Mildner, Storka, Lichtenauer, Mlitz, Ghannadan, Hoetzenecker, Nickl, Dome, Tschachler, Ankersmit: Primary sources and immunological prerequisites for sST2 secretion in humans. in Cardiovascular research 2010 (PubMed)
    Show all 6 references for ABIN2666662

  3. Human Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2002684 : Cayrol, Girard: The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 3 references for ABIN2002684

  4. Human Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN1344110 : Iikura, Suto, Kajiwara, Oboki, Ohno, Okayama, Saito, Galli, Nakae: IL-33 can promote survival, adhesion and cytokine production in human mast cells. in Laboratory investigation; a journal of technical methods and pathology 2007 (PubMed)
    Show all 3 references for ABIN1344110

  5. Dog (Canine) Interleukin 33 Protein expressed in Escherichia coli (E. coli) - ABIN2008834 : Schmitz, Owyang, Oldham, Song, Murphy, McClanahan, Zurawski, Moshrefi, Qin, Li, Gorman, Bazan, Kastelein: IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. in Immunity 2005 (PubMed)
    Show all 2 references for ABIN2008834

More Proteins for Interleukin 33 (IL33) Interaction Partners

Human Interleukin 33 (IL33) interaction partners

  1. In a CML (show BCR Proteins) patient with pruritus receiving imatinib mesylate, IL-31 (show IL31 Proteins) and IL-33 serum levels were significantly higher than controls. Imatinib could cause keratinocyte injury, the release of IL-33, and the consequent interaction with its receptor on mast cells, inducing IL-31 (show IL31 Proteins) secretion. The IL-31 (show IL31 Proteins)/IL-33 axis may be involved in the pathogenesis of skin side effects related to imatinib mesylate treatment.

  2. IL-33 and ST2 are expressed in periapical granulomas and radicular cysts.

  3. in breast tumors from 40 female patients with absent or present tumor necrosis there was significantly higher expression of IL-33, IL-33R and VEGF in breast cancer tissues with absent tumor necrosis. Both, IL-33 and IL-33R expression correlated with VEGF expression in tumor cells.

  4. Data suggest that interleukin 33 (IL-33) may play an important role in the development of non-small cell lung cancer (NSCLC) and the targeted therapy.

  5. rs7044343 polymorphism of IL-33 gene is associated with the susceptibility to systemic sclerosis in Turkish population.

  6. In mild untreated asthma, the expression of IL-33 mRNA in bronchial mucosa is related to innate immune activation and allergic sensitization to HDM (show HDAC3 Proteins), rather than epithelial damage, and correlates with FeNO.

  7. Serum IL-33 levels are suppressed in Sjogren syndrome patients.

  8. Increased induction and expression of TSLP (show TSLP Proteins), IL-25 (show IL25 Proteins), and IL-33 from nasal epithelial cells contribute to the pathophysiology of eosinophilic chronic rhinosinusitis.

  9. Serum IL-33 level is increased in children with ulcerative colitis as compared with control. Serum level correlated with the disease activity.

  10. IL-33-ERK (show EPHB2 Proteins)/JNK (show MAPK8 Proteins)/p38 (show CRK Proteins)/Egr-1 (show EGR1 Proteins)/TSLP (show TSLP Proteins) axis involved in allergic skin Th2 inflammation

Mouse (Murine) Interleukin 33 (IL33) interaction partners

  1. anti-allergic effect of anti-IL-33 antibodies associated with suppression of immunoglobulin free light chain and nitric oxide synthase in a murine model of allergic rhinitis

  2. Data suggest that IL-33 and ST2 function as a developmental switch to license thermogenesis during the perinatal period.

  3. some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of Graves' disease (GD) and Hashimoto's thyroiditis (HT) in Chinese Han population.

  4. Furthermore, IL-33 injection modulates the innate immune response by polarizing microglia/macrophages toward an antiinflammatory phenotype and reducing the expression of proinflammatory genes, including IL-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins), and NLRP3 (show NLRP3 Proteins), in the cortices of APP (show APP Proteins)/PS1 (show PSEN1 Proteins) mice. Collectively, our results demonstrate a potential therapeutic role for IL-33 in AD.

  5. absence of IL-33 has no negative consequences in normal bone homeostasis while high levels of circulating IL-33 contributes to pathological bone loss.

  6. pre-treatment with the ERK1/2 inhibitor U0126 or anti-IL-33 antibody significantly abolished the ovalbumin (show OVA Proteins)-induced airway remodeling, increased expressions of IL-33

  7. IL-33 promotes degranulation of bone marrow-derived mast cells and release of cytokines IL-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins) and TNF-alpha (show TNF Proteins).

  8. pulmonary interstitial macrophages may not be a source of IL-33 during Respiratory syncytial virus infection

  9. demonstrate a pathogenic role for IL-33-mediated eosinophilia and activation of Th2 immunity in chronic intestinal inflammation

  10. IL-33 as a novel regulator of neutrophil function in antibacterial infection

Pig (Porcine) Interleukin 33 (IL33) interaction partners

  1. IL-33 may be a key molecule operating in eosinophil-mediated fibrosis in high-dose-per fraction irradiated skin.

Interleukin 33 (IL33) Protein Profile

Protein Summary

IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4\; MIM 147780). IL33 is a ligand for IL33R (IL1RL1\; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010

Gene names and symbols associated with Interleukin 33 Proteins (IL33)

  • interleukin 33 (IL33)
  • interleukin 33 (Il33)
  • interleukin 33-like (LOC100356081)
  • interleukin-33-like (LOC100518643)
  • 9230117N10Rik protein
  • C9orf26 protein
  • DVS27 protein
  • Il-33 protein
  • Il1f11 protein
  • IL33 protein
  • NF-HEV protein
  • NFEHEV protein
  • RGD1311155 protein
  • RP11-575C20.2 protein

Protein level used designations for Interleukin 33 Proteins (IL33)

interleukin 33 , IL-33 , interleukin-33 , DVS27-related protein , IL-1F11 , interleukin-1 family member 11 , nuclear factor for high endothelial venules , nuclear factor from high endothelial venules

GENE ID SPECIES
737537 Pan troglodytes
100171950 Pongo abelii
90865 Homo sapiens
77125 Mus musculus
361749 Rattus norvegicus
100715993 Cavia porcellus
403810 Canis lupus familiaris
507054 Bos taurus
101116705 Ovis aries
100356081 Oryctolagus cuniculus
100518643 Sus scrofa
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