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ICA1 encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. Additionally we are shipping Islet Cell Autoantigen 1, 69kDa Proteins (12) and Islet Cell Autoantigen 1, 69kDa Kits (6) and many more products for this protein.
Showing 10 out of 89 products:
Human Polyclonal ICA1 Primary Antibody for ICC, IF - ABIN4320779
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Cow (Bovine) Polyclonal ICA1 Primary Antibody for IHC, WB - ABIN2785861
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
ICA69 deficiency promoted formalin-induced long-lasting pain hypersensitivity.
direct link between compromised thymic ICA69 expression and autoimmunity against multiple ICA69-expressing organs, and identify a potential novel mechanism for the development of multi-organ autoimmune diseases.
C-terminal domain of ICA69 interacts with PICK1 (show PICK1 Antibodies) and acts on trafficking of PICK1 (show PICK1 Antibodies)-PKCalpha (show PKCa Antibodies) complex and cerebellar plasticity.
PICK1 (show PICK1 Antibodies) and ICA69 are key regulators of the formation and maturation of insulin (show INS Antibodies) granules.
polymorphisms within the NOD Ica1 core promoter may determine AIRE (show AIRE Antibodies)-mediated down-regulation of ICA69 expression in medullary thymic epithelial cells.
ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide
Novel association was found between intraocular pressure and a common variant at 7p21 near to GLCCI1 (show GLCCI1 Antibodies) and ICA1.
ICA69 as a novel Rab2 (show RAB2A Antibodies) effector and its role in regulating the early transport of insulin (show INS Antibodies) secretory granule proteins
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene.
islet cell autoantigen 1, 69kDa
, Islet cell autoantigen 1
, islet cell autoantigen 1-like
, 69 kDa islet cell autoantigen
, islet cell autoantigen 1, 69 kDa
, islet cell autoantigen p69
, diabetes mellitus type I autoantigen
, islet cell autoantigen 1
, islet cell autoantigen 1 isoform