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ICA1 antibody (C-Term)

ICA1 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785862
  • Target See all ICA1 Antibodies
    ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 53
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit
    Host
    • 53
    • 5
    Rabbit
    Clonality
    • 54
    • 4
    Polyclonal
    Conjugate
    • 23
    • 10
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICA1 antibody is un-conjugated
    Application
    • 54
    • 25
    • 15
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    NMKDLQASLQ EPAKAASDLT AWFSLFADLD PLSNPDAVGK TDKEHELLNA
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ICA1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ICA1
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    Discover our top product ICA1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 483 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))
    Alternative Name
    ICA1 (ICA1 Products)
    Synonyms
    ica1 antibody, MGC52730 antibody, ICA1 antibody, DKFZp469G0321 antibody, zgc:92566 antibody, 69kDa antibody, ICA69 antibody, Ica69 antibody, MGC83241 antibody, ICAp69 antibody, islet cell autoantigen 1 L homeolog antibody, islet cell autoantigen 1 antibody, Islet cell autoantigen 1 antibody, islet cell autoantigen 1 S homeolog antibody, ica1.L antibody, ICA1 antibody, ica1 antibody, ica69 antibody, Ica1 antibody, ica1.S antibody
    Background
    ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
    Alias Symbols: ICA69, ICAp69
    Protein Interaction Partner: RAB2B, ING5, MBD3, CCDC28A, RAB2A, tbc-8, EXOC5, STK16, MKKS, KRT33B, CNTF,
    Protein Size: 483
    Molecular Weight
    53 kDa
    Gene ID
    3382
    NCBI Accession
    NM_022307, NP_071682
    UniProt
    Q05084
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