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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Additionally we are shipping IARS Kits (10) and IARS Proteins (4) and many more products for this protein.
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Mutations in isoleucyl tRNA synthetase (iars(y68)) leads to increased branching angiogenesis in developing zebrafish.
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.
isoleucyl-tRNA synthetase, cytoplasmic
, isoleucine tRNA synthetase
, isoleucyl-tRNA synthetase
, isoleucine--tRNA ligase, cytoplasmic
, isoleucine-tRNA synthetase
, isoleucyl tRNA synthetase
, isoleucine tRNA ligase 1, cytoplasmic