Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 Proteins (KIR2DL3)

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Additionally we are shipping KIR2DL3 Antibodies (147) and KIR2DL3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KIR2DL3 3804 P43628
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Top KIR2DL3 Proteins at antibodies-online.com

Showing 9 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human KIR2DL3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2 to 3 Days
$286.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
$752.00
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$329.18
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 6 to 8 Days
$467.86
Details
HOST_HEK-293 Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$955.63
Details

KIR2DL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , ,

Top referenced KIR2DL3 Proteins

  1. Human KIR2DL3 Protein expressed in HEK-293 Cells - ABIN2181421 : Colonna, Samaridis: Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. in Science (New York, N.Y.) 1995 (PubMed)
    Show all 4 references for 2181421

  2. Human KIR2DL3 Protein expressed in Human Cells - ABIN2005332 : Maenaka, Juji, Stuart, Jones: Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I. in Structure (London, England : 1993) 1999 (PubMed)
    Show all 3 references for 2005332

More Proteins for Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) interaction partners

  1. CD16+ cells were significantly more frequent among Natural Killer (NK) cells negative for the inhibitory KIR (iKIR) KIR2DL1, KIR2DL3, and KIR3DL1 than those positive for any one of these iKIR to the exclusion of the others, making iKIR+ NK cells poorer antibody dependent cellular cytotoxicity effectors than iKIR- NK cells.

  2. These results show that 2DL3(+) NK cells are mediators of HIV-specific responses. Furthermore, responses of NK cell populations to iCD4 are influenced not only by NK cell education through specific KIR/HLA pairs, but also by differential HIV-mediated changes in HLA expression.

  3. Results identified three SNPs (S320F, H245Y, and H77Y) as highly deleterious in KIR2DL3 and nine SNPs (R157Q, H156Y, S63L, R157 W, F179 V, H128R, T101 M, R180C and F176I) in case of IFNL3 (show IL28B Proteins), in coding region only with high conservation ranks highlighting the functional SNPs on phenotypic variability and disease susceptibility on HCV clearance candidate genes.

  4. KIR2DL2/KIR2DL3-glutamate(35) alleles are functionally stronger than -glutamine(35) alleles.

  5. KIR2DL2 (show KIR2DL2 Proteins)/2DS2-C1C1 genotype is associated with type 1 diabetes in Saudi children

  6. study compared KIR gene repertoire of HIV-1 positive with exposed uninfected (EU)) infants to elucidate its association with transmission; results revealed presence of significantly high frequencies of activating gene KIR 2DS5 and inhibitory gene KIR 2DL3 in EU infants as compared to HIV-1 positive infants

  7. genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2 (show KIR2DL2 Proteins), KIR2DS4 (show KIR2DS4 Proteins), KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.

  8. Allelic polymorphism of KIR2DL2 (show KIR2DL2 Proteins)/2DL3 in a southern Chinese population.

  9. The authors have identified a deleterious effect of the KIR2DL3-HLA-C1 receptor-ligand combination on HIV clinical outcomes in a Thai cohort.

  10. Single Nucleotide Polymorphism in KIR2DL3 gene is associated with Asthma and Atopic Dermatitis.

KIR2DL3 Protein Profile

Protein Summary

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Gene names and symbols associated with KIR2DL3

  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 (KIR2DL3)
  • CD158b protein
  • CD158B2 protein
  • GL183 protein
  • KIR-023GB protein
  • KIR-K7b protein
  • KIR-K7c protein
  • KIRCL23 protein
  • NKAT protein
  • NKAT2 protein
  • NKAT2A protein
  • NKAT2B protein
  • p58 protein

Protein level used designations for KIR2DL3

CD158 antigen-like family member B2 , MHC class I NK cell receptor , NK-receptor , NKAT-2 , killer cell immunoglobulin-like receptor 2DL3 , killer inhibitory receptor cl 2-3 , natural killer associated transcript 2 , natural killer cell inhibitory receptor KIR2DL3 , natural killer-associated transcript 2 , p58 NK receptor CL-6 , p58 natural killer cell receptor clone CL-6 , p58.2 MHC class-I specific NK receptor , p58.2 MHC class-I-specific NK receptor

GENE ID SPECIES
3804 Homo sapiens
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