KIR2DL3 Protein (AA 22-245) (His-Avi Tag)
-
- Target See all KIR2DL3 Proteins
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-245
- Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KIR2DL3 protein is labelled with His-Avi Tag.
- Purpose
- Human KIR2DL3 Protein
- Sequence
- His22-His245
- Characteristics
- Recombinant Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
-
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) protein (His-Avi Tag,Biotin)
KIR2DL3 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 1-341) protein (GST tag)KIR2DL3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-245) protein (His tag)Crystallography grade KIR2DL3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) (AA 22-341) protein (rho-1D4 tag)Crystallography grade KIR2DL3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))
- Alternative Name
- KIR2DL3 (KIR2DL3 Products)
- Synonyms
- CD158B2 Protein, CD158b Protein, GL183 Protein, KIR-023GB Protein, KIR-K7b Protein, KIR-K7c Protein, KIRCL23 Protein, NKAT Protein, NKAT2 Protein, NKAT2A Protein, NKAT2B Protein, p58 Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 Protein, KIR2DL3 Protein
- Background
- KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
- Molecular Weight
- 27.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result.
- UniProt
- P43628
- Pathways
- Cancer Immune Checkpoints
-
