anti-Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Antibodies

KCNIP3 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Additionally we are shipping Kv Channel Interacting Protein 3, Calsenilin Proteins (14) and Kv Channel Interacting Protein 3, Calsenilin Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNIP3 30818 Q9Y2W7
KCNIP3 56461 Q9QXT8
KCNIP3 65199 Q9JM47
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Top anti-Kv Channel Interacting Protein 3, Calsenilin Antibodies at antibodies-online.com

Showing 10 out of 142 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CSEN Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from K562 cells treated with forskolin 40nM 30' and 293 cells treated with PMA 125ng/ml 30', using Calsenilin/KCNIP3 (Phospho-Ser63) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using Calsenilin/KCNIP3 (Phospho-Ser63) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of KChIP3 Antibody (N-term M1) (ABIN388402) in mouse heart tissue lysates (35 µg/lane). KChIP3(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from MCF-7/Jurkat/A549 cells, using Calsenilin/KCNIP3 (Ab-63) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Calsenilin/KCNIP3 (Ab-63) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: Calsenilin Antibody [NBP2-26112] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCNIP3 with C-terminal MYC tag probed with EB10526 (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB10526 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Goat Un-conjugated ELISA, WB Western Blot: Calsenilin Antibody [NBP2-26111] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCNIP3 with C-terminal MYC tag probed with EB10525 (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB10525 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated WB Anti- CSEN antibody, Western blotting All lanes: Anti CSEN  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: U87 Whole Cell Lysate at 40ug Lane 3: SHG Whole Cell Lysate at 40ug Predicted bind size: 29KD Observed bind size: 29KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Image Western Blot analysis of KCNIP3 expression in transfected 293T cell line by KCNIP3 polyclonal antibody. A: Non-transfected lysate. B: KCNIP3 transfected lysate. 12% SDS PAGE antibody diluted at 1:500 WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details

KCNIP3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Kv Channel Interacting Protein 3, Calsenilin Antibodies

  1. Human Polyclonal KCNIP3 Primary Antibody for EIA, IHC (p) - ABIN357125 : Choi, Miller, Zaidi, Salih, Buxbaum, Wasco: Phosphorylation of calsenilin at Ser63 regulates its cleavage by caspase-3. in Molecular and cellular neurosciences 2003 (PubMed)
    Show all 5 references for 357125

  2. Cow (Bovine) Polyclonal KCNIP3 Primary Antibody for IHC, WB - ABIN2777506 : Zaidi, Thomson, Choi, Buxbaum, Wasco: Intracellular calcium modulates the nuclear translocation of calsenilin. in Journal of neurochemistry 2004 (PubMed)
    Show all 2 references for 2777506

  3. Human Polyclonal KCNIP3 Primary Antibody for IF, IHC - ABIN1532665 : Terman, Carrion, Kovacs, Rasmussen, Eddy, Shows: Identification of a new endothelial cell growth factor receptor tyrosine kinase. in Oncogene 1991 (PubMed)
    Show all 2 references for 1532665

  4. Human Polyclonal KCNIP3 Primary Antibody for IF, IHC - ABIN1531643 : Sjöblom, Jones, Wood, Parsons, Lin, Barber, Mandelker, Leary, Ptak, Silliman, Szabo, Buckhaults, Farrell, Meeh, Markowitz, Willis, Dawson, Willson, Gazdar, Hartigan, Wu, Liu, Parmigiani, Park et al.: The consensus coding sequences of human breast and colorectal cancers. ... in Science (New York, N.Y.) 2006 (PubMed)
    Show all 2 references for 1531643

  5. Human Polyclonal KCNIP3 Primary Antibody for IF, IHC (p) - ABIN388402 : Schrader, Anderson, Mayne, Pfaffinger, Sweatt: PKA modulation of Kv4.2-encoded A-type potassium channels requires formation of a supramolecular complex. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 (PubMed)

  6. Human Polyclonal KCNIP3 Primary Antibody for ELISA, WB - ABIN4287519 : Rivas, Mellström, Torres, Cali, Ferrara, Terracciano, Zannini, Morreale de Escobar, Naranjo: The DREAM protein is associated with thyroid enlargement and nodular development. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

More Antibodies against Kv Channel Interacting Protein 3, Calsenilin Interaction Partners

Human Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) interaction partners

  1. This study shows the application of hydrogen-deuterium exchange mass spectrometry and site-directed mutagenesis to investigate the Ca(2 (show CA2 Antibodies)+) binding properties and the subsequent conformational changes of full-length DREAM. EF-hands undergo large conformation changes upon calcium binding even though the EF-1 (show EEF1D Antibodies) hand is not capable of binding to Ca(2 (show CA2 Antibodies)+).

  2. Our approach yields high confidence ranked target gene maps for TP53 (show TP53 Antibodies), DREAM, MMB-FOXM1 (show FOXM1 Antibodies) and RB-E2F (show E2F1 Antibodies) and enables prediction and distinction of CC regulation. A web-based atlas at www.targetgenereg.org enables assessing the regulation of any human gene of interest.

  3. downregulation of these genes through the p53 (show TP53 Antibodies)-p21 (show CDKN1A Antibodies)-DREAM-CDE/CHR pathway appears to be a principal mechanism for G2/M cell cycle arrest by p53 (show TP53 Antibodies).

  4. Our results support the hypothesis that KChIPs enhances Kv4.2 (show KCND2 Antibodies) functional expression by a 1 : 1 suppression of the N-terminal FERN domain and by producing additional positive regulatory effects on functional channel expression.

  5. GCM1 (show GCM1 Antibodies)-directed villous trophoblast differentiation is repressed by DREAM

  6. p53 (show TP53 Antibodies) can repress transcription of cell cycle genes through a p21(WAF1/CIP1 (show CDKN1A Antibodies))-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.

  7. The potassium channel interacting protein 3 (DREAM/KChIP3) heterodimerizes with and regulates calmodulin (show CALM1 Antibodies) function.

  8. expression of calsenilin leads to a disruption of presenilin 1 (show PSEN1 Antibodies)/gamma-secretase-mediated epsilon-cleavage of N-cadherin (show CDH2 Antibodies), which results in the significant accumulation of N-cadherin (show CDH2 Antibodies) C-terminal fragment 1

  9. The results show that continued human papillomavirus 16 E6/E7 expression is necessary in cervical cancer cells to prevent cell-cycle arrest by a repressive p130 (show RBL2 Antibodies)-DREAM complex.

  10. These findings suggest that calsenilin degradation is primarily mediated by the UPP (show UPP1 Antibodies) and that impairment in the UPP (show UPP1 Antibodies) may contribute to the involvement of calsenilin in disease-associated neurodegeneration.

Mouse (Murine) Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) interaction partners

  1. Genome-wide analysis of trigeminal neurons in daDREAM transgenic mice identified cathepsin L (show CTSL1 Antibodies) and the monoglyceride lipase (show MGLL Antibodies) as two new DREAM transcriptional targets related to pain.

  2. association of PS1 (show PSEN1 Antibodies) carboxyl peptide (residues 445-467, HL9 (show DDC Antibodies)) with DREAM is calcium dependent and stabilized by a cluster of three aromatic residues: F462 and F465 from PS1 (show PSEN1 Antibodies) and F252 from DREAM.

  3. The association of calcium-bound calmodulin (CaM (show Calm2 Antibodies)) with DREAM is mediated by a short amphipathic amino acid sequence located between residues 29 and 44 on DREAM.

  4. The protein DREAM decreases development of L-DOPA-induced dyskinesia in mice and reduces L-DOPA-induced expression of FosB (show FOSB Antibodies), phosphoacetylated histone H3 (show HIST3H3 Antibodies), and dynorphin-B in the striatum

  5. NS5806 directly interacts with KChIP3 and modulates the interactions between this calcium-binding protein (show GUCA1B Antibodies) and the T1 domain of the Kv4.3 (show KCND3 Antibodies) channels through reorientation of helix 10 on KChIP3

  6. studies define the critical opposing functions of DREAM and USF1 (show USF1 Antibodies) in inhibiting and inducing A20 (show TNFAIP3 Antibodies) expression

  7. GCM1 (show GCM1 Antibodies)-directed villous trophoblast differentiation is repressed by DREAM

  8. Expression of DREAM in neuroblastoma (show ARHGEF16 Antibodies) cells enhances cisplatin mediated caspase-3 (show CASP3 Antibodies) activity.

  9. Restoring CANT1 (show CANT1 Antibodies) levels in neuroblastoma (show ARHGEF16 Antibodies) clones recovered the phenotype, thus confirming a key role of CANT1 (show CANT1 Antibodies), and of the regulation of its gene by DREAM, in the control of protein synthesis and degradation

  10. In cardiomyocytes, [Ca2 (show CA2 Antibodies)+]i-activated calmodulin kinase II (CaMKII (show CAMK2 Antibodies)) activates downstreamregulatory element (DRE (show SUFUH Antibodies)) binding transcription factor DREAM, which consequently suppresses the expression of L-type calcium channel 1C-subunit gene (Cacna1c (show CACNA1C Antibodies)).

Zebrafish Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) interaction partners

  1. zebrafish calsenilin is involved in endocrine cell differentiation and morphogenesis within the pancreas

Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Antigen Profile

Protein Summary

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with KCNIP3

  • calsenilin (AaeL_AAEL007002) antibody
  • calsenilin (CpipJ_CPIJ002549) antibody
  • calsenilin (Tsp_05009) antibody
  • Kv channel interacting protein 3, calsenilin (KCNIP3) antibody
  • Kv channel interacting protein 3, calsenilin (kcnip3) antibody
  • calsenilin-like (LOC100856050) antibody
  • Kv channel interacting protein 3, calsenilin (Kcnip3) antibody
  • Kv channel interacting protein 3b, calsenilin (kcnip3b) antibody
  • 4933407H12Rik antibody
  • AI413860 antibody
  • csen antibody
  • Dream antibody
  • im:7145308 antibody
  • KChIP3 antibody
  • kcnip3 antibody
  • R74849 antibody
  • rKChIP3 antibody
  • zgc:73306 antibody

Protein level used designations for KCNIP3

calsenilin , Kv channel interacting protein 3, calsenilin , A-type potassium channel modulatory protein 3 , DRE-antagonist modulator , calsenilin, presenilin-binding protein, EF hand transcription factor , kv channel-interacting protein 3 , potassium channel interacting protein 3 , calsenilin, presenilin binding protein, EF hand transcription factor , A-type potassium channel modulating protein 3 , KChIP3 , calsenilin presenilin-binding protein EF hand transcription factor , calsenilin, presenilin-binding protein, EF hand transcription fa , downstream regulatory element-antagonist modulator

GENE ID SPECIES
5568664 Aedes aegypti
6033823 Culex quinquefasciatus
10912880 Trichinella spiralis
459401 Pan troglodytes
704307 Macaca mulatta
100135241 Xenopus (Silurana) tropicalis
100856050 Canis lupus familiaris
30818 Homo sapiens
56461 Mus musculus
65199 Rattus norvegicus
513316 Bos taurus
609135 Canis lupus familiaris
393755 Danio rerio
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