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Leucine Zipper, Down-Regulated in Cancer 1 Proteins (LDOC1)

The protein encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. Additionally we are shipping LDOC1 Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LDOC1 23641 O95751
LDOC1 434784 Q7TPY9
Rat LDOC1 LDOC1 367956  
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Top LDOC1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Pan paniscus His tag   1 mg Log in to see 56 to 66 Days
$2,317.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,317.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

LDOC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) Interaction Partners

Human Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) interaction partners

  1. Cigarette smoke-induced promoter methylation may contribute to LDOC1 downregulation, thereby conferring oncogenic features to oral cells.

  2. LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-kappaB (show NFKB1 Proteins) activation in papillary thyroid carcinoma

  3. Silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.

  4. Silencing of BEX1 (show BEX1 Proteins) and LDOC1 by promoter hypermethylation might represent a critical event in the molecular pathogenesis of oral squamous cell carcinoma (OSCC) and the male predominance of OSCC occurrence.

  5. Letter/Case Report: LDOC1/PARP1 (show PARP1 Proteins) are down-regulated in melanoma with repeated in-transit metastases.

  6. The aim of this study was to evaluate the possible differential expression of LDOC1 mRNA in leucocytes of peripheral blood of Down's syndrome subjects. compared with the normal population.

  7. Over expression of LDOC1 may explain the clinical manifestation found in patients with cryptochidism and Digeorge anomaly.

  8. LDOC1 is dramatically down-regulated in mutated chronic lymphocytic leukemia cases compared with unmutated cases, and have identified a new splice variant, LDOC1S

  9. These observations suggest that LDOC1 is a novel regulator of NF-kappaB (show NFKB1 Proteins) that can affect the PMA or TNF-alpha (show TNF Proteins)-mediated pathway to apoptosis through inhibition of NF-kappaB (show NFKB1 Proteins) activation in BxPC3 pancreatic cancer cells.

  10. MZF-1 (show ZFP42 Proteins) was revealed to interact with LDOC1 and enhance the activity of LDOC1 for inducing apoptosis

LDOC1 Protein Profile

Protein Summary

The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Gene names and symbols associated with LDOC1

  • leucine zipper, down-regulated in cancer 1 (LDOC1)
  • leucine zipper, down-regulated in cancer 1 (LOC100345630)
  • leucine zipper, down-regulated in cancer 1 (Ldoc1)
  • BCUR1 protein
  • Gm366 protein
  • LDOC1 protein
  • Mar7 protein
  • Mart7 protein
  • RGD1565644 protein

Protein level used designations for LDOC1

leucine zipper, down-regulated in cancer 1 , breast cancer, up-regulated 1 , leucine zipper protein down-regulated in cancer cells , protein LDOC1 , Protein LDOC1

GENE ID SPECIES
696902 Macaca mulatta
100345630 Oryctolagus cuniculus
23641 Homo sapiens
616591 Bos taurus
434784 Mus musculus
367956 Rattus norvegicus
492180 Canis lupus familiaris
100969658 Pan paniscus
Selected quality suppliers for LDOC1 Proteins (LDOC1)
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