Leucine Zipper, Down-Regulated in Cancer 1 Proteins (LDOC1)

The protein encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. Additionally we are shipping LDOC1 Antibodies (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LDOC1 23641 O95751
LDOC1 367956  
LDOC1 434784 Q7TPY9
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Top LDOC1 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 20 Days
$860.20
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Yeast Pan paniscus His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$600.00
Details
Escherichia coli (E. coli) Rat T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$672.00
Details

LDOC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Rat (Rattus)

Mouse (Murine)

More Proteins for Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) Interaction Partners

Human Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) interaction partners

  1. GNL3L (show GNL3L Proteins)-LDOC1 interplay regulates cell proliferation through the modulation of NF-kappaB (show NFKB1 Proteins) pathway during tumorigenesis.

  2. These finding of this study suggested that the hypothesize that LDOC1 gene upregulation may play a role in the spermatogenesis derangement observed in patients with Klinefelter Syndrome.

  3. data show that LDOC1 is a tumor suppressor in osteosarcoma, and that it regulates metastasis of osteosarcoma cells. Furthermore, LDOC1 might be a valuable prognostic marker in osteosarcomas.

  4. Cigarette smoke-induced promoter methylation may contribute to LDOC1 downregulation, thereby conferring oncogenic features to oral cells.

  5. LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-kappaB (show NFKB1 Proteins) activation in papillary thyroid carcinoma

  6. Silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.

  7. Silencing of BEX1 (show BEX1 Proteins) and LDOC1 by promoter hypermethylation might represent a critical event in the molecular pathogenesis of oral squamous cell carcinoma (OSCC) and the male predominance of OSCC occurrence.

  8. Letter/Case Report: LDOC1/PARP1 (show PARP1 Proteins) are down-regulated in melanoma with repeated in-transit metastases.

  9. The aim of this study was to evaluate the possible differential expression of LDOC1 mRNA in leucocytes of peripheral blood of Down's syndrome subjects. compared with the normal population.

  10. Over expression of LDOC1 may explain the clinical manifestation found in patients with cryptochidism and Digeorge anomaly.

LDOC1 Protein Profile

Protein Summary

The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Gene names and symbols associated with LDOC1

  • LDOC1, regulator of NFKB signaling (LDOC1)
  • LDOC1, regulator of NFKB signaling (Ldoc1)
  • regulator of NFKB signaling (Ldoc1)
  • BCUR1 protein
  • Gm366 protein
  • LDOC1 protein
  • Mar7 protein
  • Mart7 protein
  • RGD1565644 protein

Protein level used designations for LDOC1

breast cancer, up-regulated 1 , leucine zipper protein down-regulated in cancer cells , protein LDOC1 , leucine zipper, down-regulated in cancer 1 , Protein LDOC1 , leucine zipper down-regulated in cancer 1

GENE ID SPECIES
23641 Homo sapiens
367956 Rattus norvegicus
434784 Mus musculus
616591 Bos taurus
696902 Macaca mulatta
100345630 Oryctolagus cuniculus
100969658 Pan paniscus
100855971 Canis lupus familiaris
100055774 Equus caballus
100731711 Cavia porcellus
100525445 Sus scrofa
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