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The protein encoded by LAMP2 is a member of a family of membrane glycoproteins. Additionally we are shipping LAMP2 Proteins (28) and LAMP2 Kits (16) and many more products for this protein.
Showing 10 out of 430 products:
Human Monoclonal LAMP2 Primary Antibody for ICC, IF - ABIN361746
Hoening, Sandoval, von Figura: A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3. in The EMBO journal 1998
Show all 7 references for ABIN361746
Human Polyclonal LAMP2 Primary Antibody for EIA, IF - ABIN497979
Tanaka, Guhde, Suter, Eskelinen, Hartmann, Lüllmann-Rauch, Janssen, Blanz, von Figura, Saftig: Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. in Nature 2000
Show all 7 references for ABIN497979
Mouse (Murine) Monoclonal LAMP2 Primary Antibody for IF, IP - ABIN452104
Granger, Green, Gabel, Howe, Mellman, Helenius: Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells. in The Journal of biological chemistry 1990
Show all 6 references for ABIN452104
Human Polyclonal LAMP2 Primary Antibody for IF, IHC (p) - ABIN303278
Rohrer, Schweizer, Russell, Kornfeld: The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane. in The Journal of cell biology 1996
Show all 6 references for ABIN303278
Human Monoclonal LAMP2 Primary Antibody for FACS, IHC (fro) - ABIN371603
Febbraio, Silverstein: Identification and characterization of LAMP-1 as an activation-dependent platelet surface glycoprotein. in The Journal of biological chemistry 1990
Show all 4 references for ABIN371603
Human Polyclonal LAMP2 Primary Antibody for FACS, IF (p) - ABIN680198
Zhang, Fu, Sheng, Li, Song, Li, Song, Wang, Chen, Yu, Wei: Bone marrow CD11b(+)F4/80(+) dendritic cells ameliorate collagen-induced arthritis through modulating the balance between Treg and Th17. in International immunopharmacology 2015
Show all 4 references for ABIN680198
Mouse (Murine) Monoclonal LAMP2 Primary Antibody for FACS - ABIN320211
Flotte, Springer, Thorbecke: Dendritic cell and macrophage staining by monoclonal antibodies in tissue sections and epidermal sheets. in The American journal of pathology 1983
Show all 3 references for ABIN320211
Mouse (Murine) Monoclonal LAMP2 Primary Antibody for FACS - ABIN120162
Ho, Springer: Tissue distribution, structural characterization, and biosynthesis of Mac-3, a macrophage surface glycoprotein exhibiting molecular weight heterogeneity. in The Journal of biological chemistry 1983
Show all 3 references for ABIN120162
Mouse (Murine) Monoclonal LAMP2 Primary Antibody for FACS, IHC (fro) - ABIN120164
Springer: Monoclonal antibody analysis of complex biological systems. Combination of cell hybridization and immunoadsorbents in a novel cascade procedure and its application to the macrophage cell surface. in The Journal of biological chemistry 1981
Show all 3 references for ABIN120164
Human Polyclonal LAMP2 Primary Antibody for ICC, IF - ABIN152746
Xia, de Queiroz, Sriramula, Feng, Johnson, Mungrue, Lazartigues: Brain ACE2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress. in American journal of physiology. Regulatory, integrative and comparative physiology 2015
LAMP-2 in the central nervous system has a possible role in the degradation of the various macromolecules in lysosomes and an additional function concerning protection from oxidative stress, especially in the substantia nigra.
The absence of LAMP-2 in murine brain led to inflammation and abnormal behavior, including motor deficits and impaired learning.
Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure.
These results suggest that VPS35 (show vps35 Antibodies) deficiency or mutation promotes Parkinson Disease (PD) pathogenesis, and reveals a crucial pathway, VPS35 (show vps35 Antibodies)-Lamp2a-alpha-synuclein (show SNCA Antibodies), to prevent PD pathogenesis.
LAMP proteins retain TAPL (show ABCB9 Antibodies) on the limiting membrane of endosomes and prevent its sorting to intraluminal vesicles.
Restoration of lysosome-associated membrane protein-2 levels synergizes with partial BECLIN-1 (show BECN1 Antibodies) knockdown to restore autophagosome processing and to attenuate cell death after hypoxia-reoxygenation.
results suggest that LAMP-2, its luminal domain in particular, plays a critical role in endosomal cholesterol transport and that this is distinct from the chaperone-mediated autophagy function of LAMP-2
Using LAMP1 (show LAMP1 Antibodies)/2 knock out cells the authors show that these two proteins are important for Trypanosoma cruzi infection of host cells, both in entrance and intracellular development, conceivably by being the major source of sialic acid for Trypanosoma cruzi.
LAMP-2 has a role in lysosome biogenesis and autophagy
Danon's disease resulted from a yet undescribed deletion in exon 7 of lamp-2 gene.
Increased expression of LAMP2 has been observed in peripheral blood mononuclear cells of coronary artery disease patients compared to the control group.
Knockdown of LAMP2A, a CMA-related protein, and TSG101 (show TSG101 Antibodies), an mA-related protein, significantly but only partially decreased the punctate accumulation of GAPDH (show GAPDH Antibodies)-HT in AD293 cells and primary cultured rat cortical neurons.
miR (show MLXIP Antibodies)-487b-5p regulates temozolomide resistance of lung cancer cells through LAMP2-mediated autophagy.
Up-regulation of LAMP2 is associated with carcinogenesis and progression of Salivary Adenoid Cystic Carcinoma.
In our study of the EOG in Danon disease, we show for the first time to our knowledge that a LAMP2 mutation may cause a primary retinal pigment epitheliopathy.
LAMP-2C serves as a natural inhibitor of chaperone-mediated autophagy that can selectively skew MHCII presentation of cytoplasmic antigens
In the early stages of Parkinson's disease, with LAMP2A selectively reduced in association with increased alpha-synuclein, and decreased levels of heat shock cognate protein 70.
This study showed that LAMP2 upregulation occurs in vitro and in vivo in neoplastic cells.
LAMP2 has a role in differentiation of primary biliary cirrhosis
Patient B harbored a frame-shift deletion mutation in exon 3 (c.396delA) leading to a truncated LAMP2 protein
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.
lysosome-associated membrane glycoprotein 2
, lysosomal-associated membrane protein 2
, Lysosome-associated membrane glycoprotein 2
, lysosome-associated membrane glycoprotein 2-like
, CD107 antigen-like family member B
, Lysosome-associated membrane protein 2
, Lamp II
, lysosomal membrane glycoprotein 2
, lysosomal membrane glycoprotein type B
, lysosome-associated membrane protein 2
, lysosome-associated membrane protein-2
, lysosome-associated membrane glycoprotein LAMP-2