anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) Antibodies

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Additionally we are shipping MARK1 Proteins (7) and MARK1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MARK1 226778 Q8VHJ5
MARK1 117016 O08678
MARK1 4139 Q9P0L2
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Top anti-MARK1 Antibodies at antibodies-online.com

Showing 10 out of 137 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells, using MARK Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB The anti-MARK1 C-term Pab is used in Western blot to detect MARK1 in, from left to right, Hela, T47D, and mouse brain cell line/ tissue lysate. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. The anti-MARK1 N-term Pab is used in Western blot to detect MARK1 in P7 mouse whole brain lysate (60 ug). 1:250 dilution of anti-MARK1 pab was used. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MARK staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MARK staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-MARK1 N-term Pab (ABIN391219) is used in Western blot to detect MARK1 in P7 mouse whole brain lysate (60 ug). 1:250 dilution of anti-MARK1 pab was used. Data and protocol kindly provided by DR. Shengli Zhao, M.D., Ph.D. of Duke University Medical Center. Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody (N-term) (ABIN391219), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB The anti-MARK1 C-term Pab (7144b) is used in Western blot to detect MARK1 in, from left to right, Hela, T47D, and mouse brain cell line/ tissue lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Mouse Mark1 Antibody (C-term) (ABIN658190) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the Mark1 antibody detected the Mark1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Horse Rabbit Un-conjugated IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with MARK1 antibody ABIN239803 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Bat Rabbit Un-conjugated IHC (p) Human Brain, Caduate (formalin-fixed, paraffin-embedded) stained with MARK1 antibody ABIN239802 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$221.76
Details

MARK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus) ,
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Human , , ,


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Top referenced anti-MARK1 Antibodies

  1. Human Polyclonal MARK1 Primary Antibody for IHC (p), WB - ABIN391219 : Drewes, Ebneth, Preuss, Mandelkow, Mandelkow: MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. in Cell 1997 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MARK1 Primary Antibody for WB - ABIN391220 : Hezel, Gurumurthy, Granot, Swisa, Chu, Bailey, Dor, Bardeesy, Depinho: Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. in Molecular and cellular biology 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against MARK1 Interaction Partners

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) interaction partners

  1. In vitro kinase assays and metabolic-labeling experiments in living cells confirmed MARK1 as an LRRK2 (show LRRK2 Antibodies) substrate. Moreover, we also showed that LRRK2 (show LRRK2 Antibodies) and MARK1 are interacting in eukaryotic cells.

  2. Overexpression and silencing of MARK1 resulted in significantly shorter dendrite length in mouse neocortical neurons and modified dendritic transport speed.

Human MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) interaction partners

  1. Molecular determinants of KA1 (show GRIK4 Antibodies) domain-mediated autoinhibition and phospholipid activation of MARK1 kinase have been described.

  2. the positioning of MARK/Par-1 (show MARK2 Antibodies) at the crosstalk of regulating cytoskeletal dynamics allows its participation in neuronal polarity decisions. [review]

  3. LKB1 (show STK11 Antibodies) acts through its substrates of the microtubule affinity-regulating kinase family to regulate the localization of the polarity determinant Scribble (show SCRIB Antibodies) and the activity of the core Hippo kinases

  4. In the Australian GWAS, the SNP rs7530302 near MARK1 on chromosome 1 (p=1.90 x 10(-9) achieved genomewide significance for comorbid AD/ND.

  5. analysis of variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2 (show MARK2 Antibodies)

  6. MARK1 was overexpressed in a prefrontal region in the brains of patients with Autism spectrum disorders.

MARK1 Antigen Profile

Protein Summary

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).

Gene names and symbols associated with MARK1

  • MAP/microtubule affinity-regulating kinase 1 (mark1) antibody
  • MAP/microtubule affinity-regulating kinase 1 (MARK1) antibody
  • MAP/microtubule affinity-regulating kinase 1 (Mark1) antibody
  • AW491150 antibody
  • B930025N23Rik antibody
  • Emk3 antibody
  • MARK antibody
  • MARK1 antibody
  • MGC80341 antibody
  • mKIAA1477 antibody
  • mPar-1c antibody
  • Par-1c antibody
  • Par1c antibody

Protein level used designations for MARK1

MAP/microtubule affinity-regulating kinase 1 , chemokine CCL-CUc , serine/threonine-protein kinase MARK1 , serine/threonine-protein kinase MARK1-like , ELKL motif serine-threonine protein kinase 3 , ELKL motif serine/threonine-protein kinase 3 , PAR1 homolog c

GENE ID SPECIES
432201 Xenopus laevis
469683 Pan troglodytes
100003170 Danio rerio
100456064 Pongo abelii
100559635 Anolis carolinensis
226778 Mus musculus
117016 Rattus norvegicus
4139 Homo sapiens
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