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As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Additionally we are shipping MOCO Sulphurase C-terminal Domain Containing 1 Antibodies (25) and MOCO Sulphurase C-terminal Domain Containing 1 Proteins (8) and many more products for this protein.
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Functional characteristics of protein variants encoded by nonsynonymous single nucleotide polymorphisms in MARC1 and MARC2 in healthy Caucasians were determined.
human mARC-1 and mARC-2 are capable of catalyzing reduction of nitrite to NO through reaction with its molybdenum cofactor
Data indicate that mitochondrial amidoxime reducing components 1 and 2 together with the electron transport proteins NADH-cytochrome b5 reductase (CYB5R) and cytochrome b5 (CYB5 (show CYB5A ELISA Kits)) catalyze the reduction of N-hydroxylated compounds such as amidoximes.
The transmembrane domain of mARC1 shown to be sufficient for mitochondrial targeting and the N-terminal targeting signal to function as a supportive receptor for the outer mitochondrial membrane.
Chlamydomonas reinhardtii ARC has a Zn-dependent activity and protein partners similar to human MARC1 and MARC2.
results provide the first hints that mARC (show CCL7 ELISA Kits) might be involved in mitochondrial N(omega)-hydroxy-L-arginine (show GATM ELISA Kits) reduction and could be of physiological significance in affecting endogenous nitric oxide levels
Arc1(MOSC-1) and Arc2(MOSC-2) proteins are monomeric in their active forms.
molybdoprotein mARC1 is involved in the activation of N-hydroxylated prodrugs.
As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively (By similarity).
MOCO sulphurase C-terminal domain containing 1
, MOSC domain-containing protein 1, mitochondrial
, moco sulfurase C-terminal domain-containing protein 1
, molybdenum cofactor sulfurase C-terminal domain-containing protein 1
, MOCO sulphurase C-terminal domain containing-like
, MOCO sulphurase C-terminal domain containing 2