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Mannose-6-Phosphate Receptor (Cation Dependent) Proteins (M6PR)

M6PR encodes a member of the P-type lectin family. Additionally we are shipping M6PR Antibodies (62) and M6PR Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
M6PR 16004 Q07113
M6PR 4074 P20645
Rat M6PR M6PR 312689 Q6AY20
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Top M6PR Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human GST tag Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) (AA 1-277), (full length) protein (GST tag) 1 mg Log in to see 56 to 66 Days
$1,842.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,069.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$510.36
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

M6PR Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

More Proteins for Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Interaction Partners

Zebrafish Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Analysis of full-length sequences for MPR 46 from zebrafish (Danio rerio) and its functional analysis.

Rhesus Monkey Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.

Mouse (Murine) Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Selective M6PR down-regulation has a critical role in CD8 (show CD8A Proteins)(+) T cell survival.

  2. Expression of imprinted gene Igf2r (show IGF2R Proteins) was unregulated in haploid androgenetic/gynogenetic blastocysts.

  3. that an elevation in IGF-II receptor (show IGF2R Proteins) levels can influence the expression profiles of transcripts as well as proteins that are involved in AD pathogenesis.

  4. DNA methylation (show HELLS Proteins) changes were noted in the Igf2r (show IGF2R Proteins) gene during chronic cystitis in a murine model.

  5. Airn expression is both necessary and sufficient to silence Igf2r (show IGF2R Proteins) throughout embryonic stem cell differentiation.

  6. We conclude that M6PR is an important receptor used by HIV-1 to cross the blood-brain barrier.

  7. The results excluded a role for spliced and unspliced Airn lncRNA products and for Airn nuclear size and location in silencing Igf2r. Instead, silencing only required Airn transcriptional overlap of the Igf2r promoter, which interferes with RNA polymerase II recruitment in the absence of repressive chromatin.

  8. mannose 6-phosphate/IGF2R knock-down in receptor-positive mouse hepatocytes causes increased cathepsin secretion as well as enhanced cell motility and invasiveness

  9. enhanced CI-MPR (show IGF2R Proteins) expression might improve the efficacy of enzyme replacement therapy in Pompe disease through enhancing receptor-mediated uptake of GAA (show GAA Proteins).

  10. The interaction of sM6P/IGF2R (show IGF2R Proteins) with Plg (show PLG Proteins) may be an important regulatory mechanism to inhibit migration of cells using the uPA (show PLAU Proteins)/uPAR (show PLAUR Proteins) system.

Human Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Results suggest that Rab (show HRB Proteins) protein Rab29 is essential for the integrity of the trans-Golgi network (TGN (show TG Proteins)) and participates in the retrograde trafficking of mannose-6-phosphate receptor (M6PR).

  2. These data indicate that clathrin is required for the function of AP-1 (show FOSB Proteins)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  3. Sortilin (show SORT1 Proteins) is a new alpha-Gal A receptor expressed in renal endothelial cells and that this receptor together with the M6PR (show IGF2R Proteins) is able to internalize circulating alpha-Gal A.

  4. Mannose receptor (MR) engagement by mesothelin (show MSLN Proteins) GPI (show GNPDA1 Proteins) anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody

  5. sorting of the CD-MPR in late endosomes requires a distinct di-aromatic motif with only limited possibilities for variations

  6. We conclude that the CI-MPR (show IGF2R Proteins) participates in lysosomal and granular targeting of serglycin (show SRGN Proteins) and basic proteins such as lysozyme (show LYZ Proteins) associated with the proteoglycan (show Vcan Proteins) in hematopoietic cells.

  7. sortilin (show SORT1 Proteins) and mannose-6-phosphate receptors recycle to the TGN (show TG Proteins) in SNX1 (show SNX1 Proteins)-dependent carriers, which we named endosome-to-TGN (show TG Proteins) transport carriers

  8. Missorting of cathepsin D (show CTSD Proteins) in GARP (show CNGB1 Proteins)-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes.

  9. Data demonstrate that Rab31 (show RAB31 Proteins) is required for transport of mannose 6-phosphate receptors from the trans-Golgi network to endosomes and for the Golgi/TGN (show TG Proteins) organization.

Cow (Bovine) Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.

  2. Expression and binding properties of mannose-6-phosphate receptors CD-MPR and CI-MPR (show IGF2R Proteins) differ during perinatal development in rat liver.

M6PR Protein Profile

Protein Summary

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Gene names and symbols associated with M6PR

  • mannose-6-phosphate receptor (cation dependent) (m6pr)
  • mannose-6-phosphate receptor (cation dependent) (M6PR)
  • mannose-6-phosphate receptor (cation dependent) (Ethha_1678)
  • Cation-dependent mannose-6-phosphate receptor (mprd)
  • insulin-like growth factor 2 receptor (Igf2r)
  • mannose-6-phosphate receptor, cation dependent (M6pr)
  • AI661837 protein
  • CD-MPR protein
  • CD222 protein
  • CDMPR protein
  • CI-MPR protein
  • M6P/IGF2R protein
  • M6PR protein
  • MGC68896 protein
  • MGC89423 protein
  • MGC130765 protein
  • MPR-46 protein
  • MPR 46 protein
  • Mpr46 protein
  • Mpr300 protein
  • mprd protein
  • SMPR protein
  • wu:fj81h11 protein
  • zgc:77757 protein

Protein level used designations for M6PR

mannose-6-phosphate receptor (cation dependent) , Mannose 6-Phosphate Receptor , cation-dependent mannose-6-phosphate receptor , CD-MPR , Cation-dependent mannose-6-phosphate receptor , 300 kDa mannose 6-phosphate receptor , CI Man-6-P receptor , IGF-II receptor , IGF-II/CI-MPR , M6P/IGF2 receptor , M6PR , MPR 300 , cation-independent MPR , cation-independent mannose 6-phosphate receptor , cation-independent mannose-6-phosphate receptor , insulin-like growth factor II receptor , mannose-6-phosphate receptor, cation independent , 46-kDa mannose 6-phosphate receptor , CD Man-6-P receptor , Mr 46,000 Man6PR , small mannose 6-phosphate receptor , 46 kDa mannose 6-phosphate receptor , MPR 46

GENE ID SPECIES
380564 Xenopus laevis
396044 Gallus gallus
406486 Danio rerio
493477 Xenopus (Silurana) tropicalis
496207 Xenopus laevis
716696 Macaca mulatta
736013 Pan troglodytes
10092655 Ethanoligenens harbinense YUAN-3
100194796 Salmo salar
16004 Mus musculus
4074 Homo sapiens
477700 Canis lupus familiaris
281291 Bos taurus
312689 Rattus norvegicus
17113 Mus musculus
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