M6PR Protein (AA 2328-2491, partial) (GST tag)

Catalog No. ABIN5712572

Product Details

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Protein Type: Recombinant

Protein Characteristics: AA 2328-2491, partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This M6PR protein is labelled with GST tag.

Application: SDS-PAGE (SDS)

Sequence: KKERRETVIS KLTTCCRRSS NVSYKYSKVN KEEETDENET EWLMEEIQLP PPRQGKEGQE NGHITTKSVK ALSSLHGDDQ DSEDEVLTIP EVKVHSGRGA GAESSHPVRN AQSNALQERE DDRVGLVRGE KARKGKSSSA QQKTVSSTKL VSFHDDSDED LLHI

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Alternative Name: MPRD (M6PR Products)

Synonyms: CD222 Protein, CIMPR Protein, M6P-R Protein, MPR1 Protein, MPRI Protein, CD-MPR Protein, MPR 46 Protein, MPR-46 Protein, MPR46 Protein, SMPR Protein, Mpr46 Protein, CDMPR Protein, m6pr Protein, MGC68896 Protein, MGC130765 Protein, zgc:77757 Protein, wu:fj81h11 Protein, MGC89423 Protein, M6PR Protein, mprd Protein, C16orf27 Protein, GNPTAG Protein, LP2537 Protein, RJD9 Protein, insulin like growth factor 2 receptor Protein, mannose-6-phosphate receptor, cation dependent Protein, mannose-6-phosphate receptor (cation dependent) L homeolog Protein, mannose-6-phosphate receptor (cation dependent) Protein, mannose-6-phosphate receptor (cation dependent) S homeolog Protein, Cation-dependent mannose-6-phosphate receptor Protein, N-acetylglucosamine-1-phosphate transferase gamma subunit Protein, IGF2R Protein, M6PR Protein, M6pr Protein, m6pr.L Protein, m6pr Protein, m6pr.S Protein, Ethha_1678 Protein, mprd Protein, GNPTG Protein

Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Molecular Weight: 45.7 kDa

UniProt: P20645