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Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Additionally we are shipping MCAM Proteins (30) and MCAM Kits (29) and many more products for this protein.
Showing 10 out of 506 products:
Human Monoclonal MCAM Primary Antibody for EIA, FACS - ABIN119672
Möbius-Winkler, Hilberg, Menzel, Golla, Burman, Schuler, Adams: Time-dependent mobilization of circulating progenitor cells during strenuous exercise in healthy individuals. in Journal of applied physiology (Bethesda, Md. : 1985) 2009
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Human Monoclonal MCAM Primary Antibody for FACS - ABIN4896787
Fujinaga, Baker, Ryan, Markham, Seedorf, Balasubramaniam, Abman: Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants. in American journal of physiology. Lung cellular and molecular physiology 2009
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Human Polyclonal MCAM Primary Antibody for EIA, WB - ABIN453743
Malyszko, Malyszko, Kozminski, Pawlak, Mysliwiec: Adipokines, linking adipocytes and vascular function in hemodialyzed patients, may also be possibly related to CD146, a novel adhesion molecule. in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2008
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Human Monoclonal MCAM Primary Antibody for FACS - ABIN4896789
Pilz, Braun, Ulrich, Felka, Warstat, Ruh, Schewe, Abele, Larbi, Aicher: Human mesenchymal stromal cells express CD14 cross-reactive epitopes. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011
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Human Monoclonal MCAM Primary Antibody for FACS, IHC - ABIN1724844
Wang, Yan: CD146, a multi-functional molecule beyond adhesion. in Cancer letters 2013
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Human Polyclonal MCAM Primary Antibody for FACS, IF (p) - ABIN732143
Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious. in International journal of clinical and experimental pathology 2015
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Human Monoclonal MCAM Primary Antibody for IHC, ELISA - ABIN1724898
Jouve, Despoix, Espeli, Gauthier, Cypowyj, Fallague, Schiff, Dignat-George, Vély, Leroyer: The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells. in The Journal of biological chemistry 2013
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Rat (Rattus) Monoclonal MCAM Primary Antibody for FACS - ABIN4896084
Shen, Chung, Irhimeh, Li, Lee, Gillies: Systemic administration of erythropoietin inhibits retinopathy in RCS rats. in PLoS ONE 2014
Chicken Monoclonal MCAM Primary Antibody for FACS, IHC (fro) - ABIN371423
Vainio, Dunon, Aïssi, Dangy, McNagny, Imhof: HEMCAM, an adhesion molecule expressed by c-kit+ hemopoietic progenitors. in The Journal of cell biology 1997
Human Monoclonal MCAM Primary Antibody for FACS - ABIN4896783
Albert, Veréb, Csomós, Moe, Johnsen, Olstad, Nicolaissen, Rajnavölgyi, Fésüs, Berta, Petrovski: Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium. in PLoS ONE 2012
In the context of adult zebrafish spinal cord injury, we proved that Melanoma cell adhesion molecule (MCAM) is beneficial to the recovery, possibly via mechanisms of angiogenensis and inflammation
CD146 regulates convergent extension movement during gastrulation
In addition to the physiological angiogenesis during development, gicerin morphants efficiently blocked the tumor angiogenesis in zebrafish.
CD146 protein expression has a role in vascular development in zebrafish
Our results suggest that MCAM may serve as a novel therapeutic target to overcome chemoresistance in SCLC.
Authors show that KDM3A (show KDM3A Antibodies) regulates MCAM expression both through a direct mechanism, involving modulation of H3K9 methylation at the MCAM promoter, and an indirect mechanism, via the Ets1 (show ETS1 Antibodies) transcription factor.
increment of CD146 expression indicates gradual change of cultured annulus fibrosus cells to express a contractile phenotype and that transforming growth factor beta1 enhances this cellular commitment
CD146 positivity in immunohistological analysis of 11 MRT patient samples was associated with poor patient outcomes. These results suggest that CD146 defines a distinct sub-population in MRT with high tumorigenic capacity and that this marker represents a promising therapeutic target.
Promoter methylation of MCAM, ERalpha (show ESR1 Antibodies) and ERbeta (show ESR2 Antibodies) have a potential to be utilized as biomarker for the early detection of prostate cancer (PC) as their sensitivity and specificity seem to be better than serum PSA (show PLAG1 Antibodies).
MCAM promotes tamoxifen resistance by transcriptionally suppressing ERalpha (show ESR1 Antibodies) expression and activating the AKT (show AKT1 Antibodies) pathway, followed by induction of epithelial-mesenchymal transition.
High MCAM expression is associated with lung metastasis in malignant melanoma.
Results provide evidence that MUC18 promotes viral infections both in vivo and in vitro.
soluble CD146 is released from the peripheral vasculature in response to venous stretch and may reflect systemic congestion in chronic heart failure patients
CD146/MCAM is the functional galectin-3 (show LGALS3 Antibodies)-binding ligand on endothelial cell surfaces responsible for galectin-3 (show LGALS3 Antibodies)-induced secretion of metastasis-promoting cytokines.
Study shows that Mcam is upregulated in cells that have a migratory phenotype upon MEIS1 (show MEIS1 Antibodies) overexpression and identi fi ed a MEIS1 (show MEIS1 Antibodies) consensus site 113 kb upstream of the Mcam tran- scriptional start site.
Different intrinsic co-factors in different K1735 sublines, which modulate the functions of MCAM/MUC18 in the cells that interact differently to the tumor microenvironment, may render sublines manifest differently in tumorigenicity and metastasis in vivo.
Microphthalmia-associated transcription factor (show MITF Antibodies) regulates skin melanoblast migration by repressing the melanoma cell adhesion molecule
Data show that CD146 was significantly higher expressed on tumor endothelium than on the liver.
Conditional knockout of the cd146 gene in the murine endothelium or disruption of netrin-CD146 interaction by a specific anti-CD146 antibody blocks or reduces netrin-1 (show NTN1 Antibodies)-induced angiogenesis.
MCAM is expressed by encephalitogenic CD8 (show CD8A Antibodies)+ T lymphocytes in experimental autoimmune encephalomyelitis. Blocking or depleting MCAM in vivo reduces chronic neurological deficits in active, transfer, and spontaneous progressive EAE models.
Study demonstrate for the fi rst (show SLC22A12 Antibodies) time that host CD146 contributes to hematogenous melanoma cell metastasis through a novel mechanism involving the VEGF (show VEGFA Antibodies)/FAK (show PTK2 Antibodies)/Ve-cadherin (show CDH5 Antibodies) network.
Suggest endothelial CD146 as a target for specific drug delivery in hepatocellular carcinoma.
CD146 plays a dual role on endothelium, facilitating leukocyte extravasations and angiogenesis, thus promoting inflammation.
expression of FLK1 (show KDR Antibodies), CD146 and microvessel density of angiogenesis at the first week of reperfused acute myocardial infarction.
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
cell surface glycoprotein MUC18
, melanoma adhesion molecule
, cell adhesion molecule
, similar to melanoma cell adhesion molecule
, melanoma cell adhesion molecule
, cell surface glycoprotein MUC18-like
, S-endo 1 endothelial-associated antigen
, cell surface glycoprotein P1H12
, melanoma-associated antigen A32
, melanoma-associated antigen MUC18
, l-gicerin protein