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MEOX2 encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. Additionally we are shipping Mesenchyme Homeobox 2 Proteins (8) and Mesenchyme Homeobox 2 Kits (1) and many more products for this protein.
Showing 10 out of 105 products:
Human Monoclonal MEOX2 Primary Antibody for IF, IHC (p) - ABIN561806
Wu, Hu, Chen, Zhang, Li, Xiong, Li: MicroRNA-130a mediates proliferation of vascular smooth muscle cells in hypertension. in American journal of hypertension 2011
Cow (Bovine) Polyclonal MEOX2 Primary Antibody for WB - ABIN2777535
Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006
Show all 2 Pubmed References
Cow (Bovine) Polyclonal MEOX2 Primary Antibody for WB - ABIN2780726
Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ... in Genome research 2006
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Findings suggest that miR (show MLXIP Antibodies)-130a may be involved in the development of obstructive sleep apnea hypopnea syndrome-associated pulmonary hypertension by down-regulating GAX gene
MEOX2 may serve a protective role, enabling increased vessel formation despite exposure to a diabetes mellitus intrauterine environment.
3D topography transiently induces concomitant upregulation of IL-1beta (show IL1B Antibodies) and MAPK (show MAPK1 Antibodies) ERK1/2 (show MAPK1/3 Antibodies) through nuclear factor-kappaB-dependent signaling pathway.
MEOX2 participates in chemoresistance irrespective of high CNV, but it is significantly dependent upon H3K27me3 enrichment probably associated with aggressiveness and chemotherapy failure in NSCLC patients
Genetic variation in MEOX2, but not TCF15 (show TCF15 Antibodies), is a strong predictor of CHD (show CHDH Antibodies). Further experimental studies should elucidate the underlying molecular mechanisms.
Microarray profiling on freshly isolated ECs had a genetic signature for microvascular heart ECs and identified Meox2/Tcf15 (show TCF15 Antibodies) heterodimers as novel transcriptional determinants. This signature was similar in skeletal muscle and adipose tissue endothelium.
downregulated expression of GAX is an independent prognostic factor and is correlated with poor survival in hepatocellular carcinoma patients
MEOX1 (show MEOX1 Antibodies) and MEOX2 activate p16(INK4a (show CDKN2A Antibodies)) in a DNA binding dependent manner, whereas they induce p21(CIP1/WAF1 (show CDKN1A Antibodies)) in a DNA binding independent manner.
Report of an interaction between a homeobox protein and IkappaBbeta (show NFKBIB Antibodies) in endothelial cells and suggest that MEOX2 modulates the activity of the RelA (show NFkBP65 Antibodies) complex through direct interaction with its components.
homeobox protein Gax is expressed in vascular endothelium and strongly inhibits endothelial cell activation in response to growth factors and tube formation in vitro
Chemerin (show RARRES2 Antibodies)-CMKLR1 (show CMKLR1 Antibodies) activates Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) and ERK (show EPHB2 Antibodies) pathways and facilitates preadipocyte proliferation, adipogenesis, and angiogenesis. Gax weakens the effect of chemerin (show RARRES2 Antibodies) on preadipocyte biofunctions.
Meox2 haploinsufficiency increases neuronal cell loss in Alzheimer's disease.
The miRNA family miR (show MLXIP Antibodies)-130/301/721 enhances induced pluripotent stem cells generation via repression of Meox2.
Results demonstrate that Meox1 (show MEOX1 Antibodies) and Meox2 genes function together and upstream of several genetic hierarchies that are required for the development of somites.
reduction of Meox-2 function is associated with susceptibility to cleft palate
Meox2 binding to RNF10 (show RNF10 Antibodies) protein, human, was characterized.
ectopic Meox2 suppressed epithelial cell proliferation in cooperation with TGF-beta1 (show TGFB1 Antibodies), and mediated induction of the cell cycle inhibitor (show CDKN2A Antibodies) gene p21 (show D4S234E Antibodies).
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease.
mesenchyme homeobox 2
, growth arrest-specific homeo box
, mesenchyme homeobox 2 a
, homeobox protein MOX-2
, mesenchyme homeo box 2 (growth arrest-specific homeo box)
, growth arrest-specific homeobox
, growth arrest homeobox transcription factor GAX
, homeobox protein MOX-2 b
, mesenchyme homeobox 2 b