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anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2) Antibodies

MTHFD2 encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. Additionally we are shipping Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Proteins (7) and Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTHFD2 17768 P18155
MTHFD2 10797 P13995
MTHFD2 680308  
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Top anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MTHFD2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of MTHFD2 antibody (C-term) (ABIN391542) in NCI-H460 cell line lysates (35 µg/lane). MTHFD2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human Colon carcinoma reacted with MTHFD2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T B: A431 , C: H1299 D: Hela E: Hep G2 , F: Molt-4 , G: Raji 10% SDS PAGE antibody diluted at 1:1000 IP Image Immunoprecipitation of MTHFD2 protein from 293T whole cell extracts using 5 μg of MTHFD2 antibody [N1C3], Western blot analysis was performed using MTHFD2 antibody [N1C3], EasyBlot anti-Rabbit IgG  was used as a secondary reagent. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB Western Blot analysis of MTHFD2 expression in transfected 293T cell line by MTHFD2 monoclonal antibody (M01), clone 4G7-2G3. Lane 1: MTHFD2 transfected lysate(26.8 KDa). Lane 2: Non-transfected lysate. MTHFD2 monoclonal antibody (M01), clone 4G7-2G3 Western Blot analysis of MTHFD2 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

MTHFD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,
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Rat (Rattus)


Top referenced anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Antibodies

  1. Human Polyclonal MTHFD2 Primary Antibody for FACS, IHC (p) - ABIN391542 : Wang, Maurer, Morton, Habermann, Davis, Cozen, Lynch, Severson, Rothman, Chanock, Hartge, Cerhan: Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma. in Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009 (PubMed)
    Show all 2 references for ABIN391542

  2. Chicken Polyclonal MTHFD2 Primary Antibody for WB - ABIN2782447 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

More Antibodies against Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Interaction Partners

Mouse (Murine) Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2) interaction partners

  1. A mutation in methylenetetrahydrofolate reductase (MTHFR (show MTHFR Antibodies)) gene, may contribute to the risk of both arterial and deep-vein thrombosis in patients with nephrotic syndrome.

Human Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2) interaction partners

  1. These findings suggest a previously unknown role for MTHFD2 in cancer cell proliferation, adding to its known function in mitochondrial folate metabolism.

  2. The highest scoring pathway is mitochondrial one-carbon metabolism and is centred on MTHFD2.

  3. Data indicate that methylenetetrahydrofolate dehydrogenase (NADP + -dependent) 2 (MTHFD2)was differentially expressed in breast cancer tissue, suggesting as a prognostic factor and a potential therapeutic target for future breast cancer treatments.

  4. Data indicate that the reduced vimentin (show VIM Antibodies) expression in response to EPHB4 (show EPHB4 Antibodies), WIPF2 (show WIPF2 Antibodies) and MTHFD2 silencing was observed at mRNA and protein levels.

Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2) Antigen Profile

Protein Summary

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

Gene names and symbols associated with MTHFD2

  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (mthfd2) antibody
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) antibody
  • methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (mthfd2) antibody
  • methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (Mthfd2) antibody
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (Mthfd2) antibody
  • AW558851 antibody
  • NMDMC antibody
  • wu:fb38b11 antibody
  • wu:fe12e11 antibody
  • zgc:91891 antibody

Protein level used designations for MTHFD2

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial , methylene tetrahydrofolate dehydrogenase 2 , methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase , methylenetetrahydrofolate dehydrogenase 2 , NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase , methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase , methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase

GENE ID SPECIES
432317 Xenopus laevis
459331 Pan troglodytes
100053990 Equus caballus
100170462 Xenopus (Silurana) tropicalis
100584729 Nomascus leucogenys
446641 Xenopus laevis
17768 Mus musculus
426126 Gallus gallus
10797 Homo sapiens
483107 Canis lupus familiaris
517539 Bos taurus
680308 Rattus norvegicus
100004977 Danio rerio
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