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The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1\; MIM 179710). Additionally we are shipping METTL11A Antibodies (35) and METTL11A Kits (1) and many more products for this protein.
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Human METTL11A Protein expressed in Escherichia coli (E. coli) - ABIN2004119
Li, Silverman, Goldberg: Incisional hernia repair in renal transplantation patients. in Hernia : the journal of hernias and abdominal wall surgery 2006
NRMT1 adopts a core methyltransferase fold that resembles DOT1L (show DOT1L Proteins) and PRMT but not SET domain family histone methyltransferases.
kinetic mechanism of NTMT1
Peptide methylation assays and substrate immunoprecipitations demonstrate that the canonical M-X-P-K methylation motif is not the only one recognized by NRMT.
discovery of the first alpha-N-methyltransferase, which we named N-terminal RCC1 methyltransferase (NRMT).
The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1\; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200).
N-terminal Xaa-Pro-Lys N-methyltransferase 1
, X-Pro-Lys N-terminal protein methyltransferase 1A
, alpha N-terminal protein methyltransferase 1A
, methyltransferase-like protein 11A
, Alpha N-terminal protein methyltransferase 1A
, Methyltransferase-like protein 11A
, N-terminal RCC1 methyltransferase
, methyltransferase like 11A